This is how the superbug Pseudomonas aeruginosa reacts to antibiotics
The bacterium Pseudomonas aeruginosa is resistant to all antibiotics on the market. Therefore, there is a great need for new therapeutic approaches. In order to find them, it helps to understand how the germ reacts to active substances......»»
Research reveals new starting points for the rapid and targeted development of future drugs
Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products of bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools for synthetic biology. By.....»»
New tuberculosis study offers a novel paradigm for understanding bacterial transcription
The bacterium behind tuberculosis is a wily foe, adept at bobbing and weaving around the immune system and antibiotics alike. Mycobacterium tuberculosis (Mtb) has been notoriously difficult to eradicate, often dormant in the body for years only to re.....»»
New starting point discovered in the fight against P. aeruginosa
Pseudomonas aeruginosa is an important opportunistic pathogen responsible for life-threatening infections that are associated with high rates of morbidity and mortality. Researchers from TWINCORE, the Center for Experimental and Clinical Infection Re.....»»
Sugar-coated gold nanoparticles can quickly eliminate bacterial infections, no antibiotics required
If left to their own devices, bacteria on our teeth or wounded skin can encase themselves in a slimy scaffolding, turning into what is called biofilm. These bacteria wreak havoc on our tissue and, being shielded from antibiotic medication by the slim.....»»
Study reveals "considerable farmer knowledge" on aspects of antibiotics risk
A study published in CABI Agriculture and Bioscience has revealed "considerable farmer knowledge" on different aspects of antibiotics risks—including antimicrobial resistance—associated with their use on livestock in Kenya......»»
Blighia sapida: A tropical fruit with antimicrobial properties
Antimicrobial resistance (AMR) remains 1 of the top 3 global public health challenges facing humanity. Every year, 70,000 people die globally from AMR, and the threat is exacerbated by the fact that we have moved from the era of excess antibiotics to.....»»
Researchers focus on finding flaws in superbugs" armor
Recent years have seen the rise of bacterial pathogens that have developed resistance to antibiotics. One such superbug, carbapenem-resistant Acinetobacter baumannii (CRAB), kills hundreds of critically ill patients in the U.S. each year, usually in.....»»
Scientists deliver portable total chemical analysis without pumps and tubes
Researchers from Tokyo Metropolitan University have engineered a new micro total analysis system that quantifies a target chemical in a microfluidic chip without pumps, tubes, and expensive detectors. The compound reacts with other chemicals to produ.....»»
Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
About a decade ago, researchers in UC Santa Barbara chemistry professor Guillermo Bazan's lab began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing th.....»»
Antibiotic use on Kenya"s dairy farms is putting consumers and animals at risk
Farmers often use antibiotics to keep their livestock healthy. They're sometimes used as "quick fixes", to avoid more costly management measures like regular disinfection, waste management, routine vaccination or provision of clean drinking water......»»
A Virus Found in Wastewater Beat Back a Woman’s ‘Zombie’ Bacteria
Viruses called phages are a promising treatment option for bacterial infections when antibiotics stop working, but they have limitations......»»
New research highlights implications of antibiotic use in human and veterinary medicine
A series of five research publications on Antimicrobial Resistance (AMR) by APC Microbiome Ireland yields new data regarding the implications of antibiotic use in early life and the effects of antibiotics in standard dry cow therapy......»»
New research shows that the arrangement of bacteria in biofilms affects their sensitivity to antibiotics
Bacteria are traditionally imagined as single-cell organisms, spread out sparsely over surfaces or suspended in liquids, but in many environments the true bacterial mode of growth is in sticky clusters called biofilms......»»
Field weed control: Synthetic microbial communities slash herbicide use
Synthetic microbial communities (SynComs) are emerging as powerful allies in the battle against weeds. These carefully crafted assemblies of microorganisms, such as compatible Pseudomonas strains, are designed to target specific weeds while promoting.....»»
New and highly infectious E. coli strain resistant to powerful antibiotics
A new type of E. coli that is both highly infectious and resistant to some antibiotics has been discovered......»»
Synthetic antibacterial minerals combat topical infections
The development of new antibiotics has stalled—new strategies are needed as the world enters the age of antibiotic resistance. To combat this challenge, Lawrence Livermore National Laboratory (LLNL) scientists have found that synthetic antibacteria.....»»
Ryan Gosling reacts to Margot Robbie and Greta Gerwig"s "Barbie" Oscar snubs
Best Supporting Actor nominee Ryan Gosling expressed disappointment at the Oscar snubs for Margot Robbie and Greta Gerwig. The nominations for the 96th Academy Awards are out, and two of the biggest snubs are without question Barbie director Gr.....»»
Study finds S. aureus" surface-sticking ability not evenly distributed over cell envelope
Infections caused by the bacterium Staphylococcus aureus have a significant impact on human health, with tens of thousands of hospital patients dying every year from infections due to the S. aureus "superbug." Stopping the spread of bacteria like S......»»
Bacterial immune system boosts antibiotic effectiveness against cholera, study reveals
Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of Tübingen and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the c.....»»
Status update in evolutionary race between humans and resistant bacteria: Two steps forward for us
In the span of one week, two researchers from Leiden are receiving their Ph.D.s, each of them on an important step in the battle against bacteria that are becoming increasingly resistant to antibiotics......»»