The hydroxylation of ASPP2 and other ankyrin repeat domain proteins
Factor Inhibiting Hypoxia Inducible Factor (FIH) has an important role in the response to low oxygen (hypoxia) in animals. FIH adds a hydroxyl (-OH) group onto the master regulator Hypoxia Inducible Factor (HIF), influencing its ability to activate h.....»»
Astronomers think they’ve found a plausible explanation of the Wow! signal
Magnetars could zap clouds of atomic hydrogen, producing focused microwave beams. Enlarge / The Wow! signal, represented as "6EQUJ5," was discovered in 1977 by astronomer Jerry Ehman. (credit: Public domain) An unusually.....»»
Ancient microbes linked to evolution of human immune proteins
When you become infected with a virus, some of the first weapons your body deploys to fight it are those passed down to us from our microbial ancestors billions of years ago. According to new research from The University of Texas at Austin, two key e.....»»
Proteins for skin strength also control cell signaling, study suggests
An extensive family of proteins that gives human skin mechanical strength also appears to organize molecular signals that control skin cell activity, a study led by UT Southwestern Medical Center researchers shows. The team's findings, published in D.....»»
Researchers teach artificial intelligence about frustration in protein folding
Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict.....»»
Unveiling the intricate and subtle dance of proteins: Understanding how parasites disarm host defenses
Pathogens hijack host cell functions by expressing or secreting effector proteins, creating environments conducive to their survival and reproduction. These pathogenic microorganisms—including eukaryotic parasites, prokaryotic bacteria, and viruses.....»»
New AI tool captures how proteins behave in context
A fish on land still waves its fins, but the results are markedly different when that fish is in water. Attributed to renowned computer scientist Alan Kay, the analogy is used to illustrate the power of context in illuminating questions under investi.....»»
The Paris Olympics saw a whole load of domain-related cybercrime
Cybercriminals targeted visitors the Paris Olympics with fake websites and social media site.....»»
Turning wastewater into valuable proteins with genetically modified yeast
The growing world population means that the environment is under great strain. Agriculture takes up large land areas and discharges nutrients to the surrounding environment. At the same time, there is tremendous pressure on the aquatic environment fr.....»»
Millions of kids are still skipping school. Could the answer be recess—and a little cash?
Flerentin "Flex" Jean-Baptiste missed so much school he had to repeat his freshman year at Medford High outside Boston. At school, "you do the same thing every day," said Jean-Baptiste, who was absent 30 days his first year. "That gets very frustrati.....»»
Light-responsive gene regulation at the mRNA level
Researchers at the University of Bayreuth have established a new optogenetic approach that can control the bacterial production of proteins at the mRNA level using blue light. The new system gates the activation of the genetic substance particularly.....»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»
Rewriting the evolutionary history of critical components of the nervous system
A new study has rewritten the conventionally understood evolutionary history of certain proteins critical for electrical signaling in the nervous system......»»
Researchers identify body"s "quality control" regulator for protein folding, could lead to targeted treatments
Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
Researchers develop AI model that predicts the accuracy of protein–DNA binding
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the t.....»»
Microscopy technique "paves way" for improving understanding of cellular functions
Scientists have developed a new way of counting labeled proteins in living cells that could become a standard and valuable tool in the field of biomedical research......»»
Study reveals how plants decide between life and death
Researchers at Michigan State University have discovered two proteins that work together to determine the fate of cells in plants facing certain stresses......»»
How ribosomes in our cells enable protein folding
Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature......»»
Ransomware gang targets IT workers with new RAT masquerading as IP scanner
Ransomware-as-a-service outfit Hunters International is wielding a new remote access trojan (RAT). “The malware, named SharpRhino due to its use of the C# programming language, is delivered through a typosquatting domain impersonating the legit.....»»
Organizations fail to log 44% of cyber attacks, major exposure gaps remain
40% of tested environments allowed attack paths that lead to domain admin access, according to Picus Security. Achieving domain admin access is particularly concerning because it is the highest level of access within an organization’s IT infrastruc.....»»