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The human GID complex engages two independent modules for substrate recruitment

A new paper by the Peter group of the ETH Zurich's Institute of Biochemistry (IBC) finds that the human GID E3 ubiquitin ligase forms a tetrameric complex with two distinct substrate-recruitment modules, namely WDR26-RanBP9 and GID4-ARMC8a. Although.....»»

Category: topSource:  pcmagOct 25th, 2021

Rounding up: How our research used round numbers to zero in on tax evasion

Australia's tax system is needlessly complex, and that's making it costly in ways that aren't obvious......»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

SpaceX shuts down launches after problem with Crew-9 mission"s 2nd stage

SpaceX celebrated the first human spaceflight from its Cape Canaveral launch site on Saturday, and while the two humans aboard the Crew Dragon Freedom are safely on their way to the International Space Station, a problem arose with the rocket's secon.....»»

Category: topSource:  physorgRelated NewsSep 30th, 2024

Octopuses work together with fish to hunt—and the way they share decisions is surprisingly complex

A new study published in Nature Ecology & Evolution lifts the veil on what happens when octopuses and fish hunt together. As it turns out, this cross-species relationship is more complex than anyone expected......»»

Category: topSource:  physorgRelated NewsSep 29th, 2024

SpaceX set to launch mission to bring Starliner astronauts back to Earth

SpaceX is bringing back propulsive landings with its Dragon capsule, but only in emergencies. Enlarge / SpaceX's Crew Dragon spacecraft is ready for launch atop a Falcon 9 rocket from Space Launch Complex-40 at Cape Canaveral Spa.....»»

Category: topSource:  arstechnicaRelated NewsSep 28th, 2024

Trimer complex TaNF-Y balances grain yield and quality in wheat: Study

Breeding efforts have focused intensively on improving grain yield and quality in wheat (Triticum aestivum L.). Content and composition of grain starch and seed storage protein (SSP) are two critical factors that determine grain yield and quality. St.....»»

Category: topSource:  physorgRelated NewsSep 27th, 2024

Enhanced denitrification achieved with innovative biochar-based substrate under low carbon/nitrogen conditions

An study led by researchers from the Harbin Institute of Technology has unveiled a substantial development in wastewater treatment technology. Published in Engineering, the research introduces an innovative approach to improving denitrification in co.....»»

Category: topSource:  physorgRelated NewsSep 27th, 2024

How a protein keeps gene clusters quiet in the cell nucleolus

In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»

Category: topSource:  informationweekRelated NewsSep 27th, 2024

Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells

Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»

Category: topSource:  theglobeandmailRelated NewsSep 27th, 2024

How large language models are changing collective intelligence

Within teams, organizations, markets and online communities, ideas from a larger group can help to solve complex problems. Large language models (LLMs) are emerging as powerful tools to unlock even greater potential. Picture an online forum where tho.....»»

Category: topSource:  theglobeandmailRelated NewsSep 27th, 2024

The 25 best YouTube videos for kids (September 2024)

Toddlers can prep for bathtime, grade schoolers do themed yoga, and older kids learn about human anatomy in the best YouTube videos for kids......»»

Category: topSource:  digitaltrendsRelated NewsSep 27th, 2024

Scientists develop method to control timing of synthetic DNA droplet division

Many cellular functions in the human body are controlled by biological droplets called liquid-liquid phase separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside living cells but are not enclosed by membranes like.....»»

Category: topSource:  marketingvoxRelated NewsSep 26th, 2024

Compliance management strategies for protecting data in complex regulatory environments

In this Help Net Security interview, Andrius Buinovskis, Head of Product at NordLayer, discusses how organizations can assess their compliance management and ensure they meet regulatory requirements. Buinovskis also addresses the challenges of managi.....»»

Category: securitySource:  netsecurityRelated NewsSep 26th, 2024

Key negotiator Norway sees "positive signals" ahead of plastic talks

In the single week that world leaders convened for high-level UN talks in New York, nearly 100,000 water bottles' worth of microplastics swirled through the city's air, posing known and still unknown risks to human health......»»

Category: topSource:  physorgRelated NewsSep 26th, 2024

UAW members at Ford"s Rouge tool and die unit reach tentative agreement

Ford's Rouge Complex near Detroit, which employs about 6,000 workers, has more than 500 workers in the tool and die unit, according to the union......»»

Category: topSource:  autonewsRelated NewsSep 26th, 2024

Improving industrial scale lactoferrin production with synthetic biological systems

Lactoferrin (LF), a multifunctional glycoprotein of the transferrin family, is naturally expressed in human and cow milk. The name "LF" is derived from its ability to bind to iron (ferrin, a suffix indicating iron-binding protein)......»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Tesla Full Self Driving requires human intervention every 13 miles

It gave pedestrians room but ran red lights and crossed into oncoming traffic. Enlarge / An independent automotive testing company has evaluated Tesla FSD, and it found some concerning results. (credit: PonyWang/Getty Images).....»»

Category: topSource:  marketingvoxRelated NewsSep 25th, 2024

Airbag deployment glitch prompts recall of nearly 17,500 Fiat vehicles

Fiat recalls 2017-20 124 Spider models to reprogram airbag control modules on behalf of Mazda......»»

Category: topSource:  autonewsRelated NewsSep 25th, 2024

Why do people breach their bail? Research shows it"s not because they"re committing more crimes

In Australia and most countries, everyone is innocent until proven guilty. Because of this, keeping someone in detention before trial comes with serious legal, practical and human-rights consequences, not just for the person accused but also for thei.....»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

Murine study suggests cosmic radiation in outer space may affect long-term cognition

During missions into outer space, galactic cosmic radiation (GCR) will penetrate current spacecraft shielding and thus pose a significant risk to human health......»»

Category: topSource:  physorgRelated NewsSep 25th, 2024

With fewer prime used cars, dealers innovate in complex market

Fewer off-lease vehicle returns predicted for 2024 and 2025 set the stage for more competition for less-aged used vehicles and higher costs to acquire them......»»

Category: topSource:  autonewsRelated NewsSep 25th, 2024