Targeting "undruggable" proteins promises new approach for treating neurodegenerative diseases
Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis.....»»
AI-driven approach reveals hidden hazards of chemical mixtures in rivers
Artificial intelligence can provide critical insights into how complex mixtures of chemicals in rivers affect aquatic life—paving the way for better environmental protection......»»
Genetically encoded biosensors measure living cells" charge in real time
Biological cells have many vital functions in the organism. For example, they produce proteins, carbohydrates and fats. But they are also responsible for detoxifying harmful molecules and transmitting signals and immune defense steps. A so-called red.....»»
Rumor Replay: Apple’s foldable iPad and iPhone are coming, AirTag 2 and more
This is Rumor Replay, a weekly column at 9to5Mac offering a quick rundown of the most recent Apple product rumors, with analysis and commentary. Today: Apple’s foldable iPad and iPhone are coming, plus a fresh Magic Mouse approach, and AirTag 2. He.....»»
Sugar solution matches antibiotics in treating cow infections
A concentrated sugar solution could be just as effective as antibiotics at treating a common infection in dairy cows, according to a new study led by researchers at Penn State. The results were recently published in the journal Frontiers in Veterinar.....»»
Researchers highlight role "workhorse protein" plays in keeping nervous system running smoothly
A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When this neurotransmission breaks down, devastating dise.....»»
Advancing a trustworthy quantum era: A novel approach to quantum protocol verification
Quantum computing offers the potential to solve complex problems faster than classical computers by leveraging the principles of quantum mechanics. Significant advancements have been made in areas, such as artificial intelligence, cryptography, deep.....»»
Study reveals how transcription factors navigate DNA architecture to shape cellular identity
A new study led by Prof. Yosef Buganim from the Hebrew University of Jerusalem and Dr. Abdenour Soufi from the University of Edinburgh reveals how transcription factors (TFs)—key proteins that regulate gene activity—navigate DNA and chromatin str.....»»
Molecular gardening: New enzymes discovered for protein modification pruning
Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including cancer and neurodegenerative disorders......»»
Study reveals how global connections boost city economies
As city population grows, so does violent crime, contagious diseases, and per-capita GDP. A significant body of research has investigated what drives this scaling relationship, examining factors within a city......»»
Ransomware in 2024: New players, bigger payouts, and smarter tactics
In 2024, ransomware remained the top cybersecurity threat to organizations worldwide. New groups filled the void left by law enforcement crackdowns, targeting businesses with record-breaking ransom demands and sophisticated tactics. In this article,.....»»
Nature"s instructions: How fungi make a key medicinal molecule
For roughly a century, ever since Alexander Fleming's accidental discovery of penicillin in 1928, fungi have proven to be a goldmine for medicines. They've provided treatments for a wide range of diseases, from infections and high cholesterol to orga.....»»
New method maps hundreds of proteins in cell nuclei simultaneously
Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei all at the same time. The method, called ChIP–DIP (Chromatin ImmunoPrecipitation Done In Parallel), is a versatile tool f.....»»
Azo-menthol: New molecule can regulate ion channels using light
Located in the cell membrane, TRPM8 ion channels are known as receptors that recognize cold and respond to menthol, the cooling agent in peppermint. In addition, these channels influence pain perception and play a key role in numerous diseases. This.....»»
NASA finalizes strategy for sustaining human presence in low Earth orbit
As part of the agency's efforts to enable broader use of space, NASA has released its final goals and objectives for low Earth orbit, defining the long-term approach toward advancing microgravity science, technology, and exploration for the benefit o.....»»
Ammonia production goes green: Biomethane approach offers net-zero emissions
Using biomethane to produce ammonia, a crucial chemical in agriculture, could drastically reduce the climate impact of the process. In a study published in One Earth, researcher Robert Istrate shows it's even possible to make ammonia production net-z.....»»
Yeast cell wall proteins offer possible alternative to emulsifiers derived from milk
Mention emulsifiers and many people might be unaware of what they are used for, but they are present in many daily products, from food to cosmetics. They keep substances that don't usually mix, like water and oil, from separating and are either synth.....»»
Instagram rolling out ‘2024 Collage’ and other year-in-review features
As we approach the end of the year, Instagram is rolling out a new year-in-review feature. This year, you’ll be able to create a collage for your Instagram Story showing off your favorite moments of the year. more….....»»
Security Bite: Realst malware returns to cash in on crypto boom
9to5Mac Security Bite is exclusively brought to you by Mosyle, the only Apple Unified Platform. Making Apple devices work-ready and enterprise-safe is all we do. Our unique integrated approach to management and security combines state-of-the-art App.....»»
MUT-1244 targeting security researchers, red teamers, and threat actors
A threat actor tracked as MUT-1244 by DataDog researchers has been targeting academics, pentesters, red teamers, security researchers, as well as other threat actors, in order to steal AWS access keys, WordPress account credentials and other sensitiv.....»»
With DORA approaching, financial institutions must strengthen their cyber resilience
The clock is ticking for financial institutions across the EU as the January 17, 2025, deadline for the Digital Operational Resilience Act (DORA) approaches. This regulation will reshape how organizations in the financial sector approach cybersecurit.....»»