Suffering from psoriasis? Blame this trio of proteins
About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies -- and.....»»
Planning a drug"s route in the body with synthetic chemistry
Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins......»»
Research provides new insights into role of mechanical forces in gene expression
The genome inside each of our cells is modeled by tension and torsion—due in part to the activity of proteins that compact, loop, wrap and untwist DNA—but scientists know little about how those forces affect the transcription of genes......»»
Seeing double: Designing drugs that target "twin" cancer proteins
Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»
Trio wanted for assault inside women"s restroom at North Wildwood bar: police
Trio wanted for assault inside women"s restroom at North Wildwood bar: police.....»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Daily 5 report for Sept. 26: This Jeep story reinforces why auto shows are suffering
What better way to make a new-vehicle splash than to do the unveiling on the 46th floor of a Tokyo high-rise with a breathtaking view of the nation's capital?.....»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
Researcher develops low-sugar ice cream with smooth texture
Wageningen researcher Qi Wang has developed a new variant of low-sugar ice cream that mimics the texture and melting properties of traditional ice cream. By replacing half of the sugar with broken-down proteins or the sweetener xylitol, she succeeded.....»»
Strategies for maximizing recombinant protein production in tobacco plants
Plant molecular farming (PMF) is a modern, sophisticated technology that utilizes plants' biosynthetic machinery to synthesize a plethora of recombinant proteins, including industrial and therapeutic enzymes. It has several advantages over traditiona.....»»
Cricket study suggests mating filter narrows when males are trying to save energy
A trio of biologists at the University of Minnesota has found that when male crickets need to save energy, they narrow their mating filter, to focus more exclusively on females......»»
Naked mole-rat found to have lost infection-resistant proteins
Scientists have found that the naked mole-rat—an underground rodent that lives up to 40 years—has lost a number of CD1 functional genes. The CD1 gene family in mammals is responsible for protein synthesis that protects the body against infectious.....»»
Chemists discover new ways in which single-celled organisms organize their DNA
It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden Ph.D. candidate Samuel Schwab has found that the histones in these organisms are much more diverse.....»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
Light-induced immunoassay can selectively detect coronavirus spike proteins in five minutes
Like moths to a flame, microbes can also be moved by light. Using this knowledge, researchers from Osaka Metropolitan University's Research Institute for Light-induced Acceleration System (RILACS) have demonstrated a method to detect the presence of.....»»
Can toddlers help explain the origins of our bias for wealth?
Income and wealth inequality in the U.S. remain near all-time highs. Analysts say this disparity is a "major issue of our time." Experts have spotlighted deep policy failures fueling the problem and helpful economic fixes to alleviate the suffering......»»
11 dead, thousands injured in explosive supply chain attack on Hezbollah pagers
Supply chain attack may be to blame. Enlarge / An ambulance arrives at the site after wireless communication devices known as pagers exploded in Sidon, Lebanon, on September 17, 2024. (credit: Ahmad Kaddoura/Anadolu via Getty Ima.....»»
8 dead, 2,700 injured after simultaneous pager explosions in Lebanon
Lithium-ion batteries or supply chain attack may be to blame. Enlarge / An ambulance arrives at the site after wireless communication devices known as pagers exploded in Sidon, Lebanon, on September 17, 2024. (credit: Ahmad Kaddo.....»»
Team discovers naturally occurring DNA-protein hybrids
Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins—without having to synthesize them one by one, res.....»»