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Suffering from psoriasis? Blame this trio of proteins

About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies -- and.....»»

Category: biomedSource:  sciencedailyNov 25th, 2021

Brazilian study identifies potential targets for treatment of visceral leishmaniasis

Researchers at the Federal University of São Carlos (UFSCar), the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil have characterized for the first time a class of proteins present in the parasite Leishmania in.....»»

Category: topSource:  physorgRelated NewsOct 14th, 2024

Glowing proteins enable real-time, 3-D study of essential enzymes

Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival. Malfunction o.....»»

Category: topSource:  physorgRelated NewsOct 14th, 2024

Trio wins economics Nobel for work on wealth inequality

The Nobel prize in economics was awarded on Monday to Turkish-American Daron Acemoglu and British-Americans Simon Johnson and James Robinson for research into wealth inequality between nations......»»

Category: topSource:  pcmagRelated NewsOct 14th, 2024

Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry

The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology's biggest challenges: predicting the 3D shape of proteins and designing them from scratch......»»

Category: topSource:  physorgRelated NewsOct 12th, 2024

Study proposes that proteins can compartmentalize and form droplets inside cells

In physics, a system composed of two substances can be modeled in accordance with classical mixture theory, which considers the fraction corresponding to each constituent and the interactions among constituents. Examples include the coexistence of hi.....»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

On US coast, wind power foes embrace "Save the Whales" argument

Whether from real concern for marine animals or doubts about renewable energy, the anti-wind power movement has been growing along the US East Coast, with some trying to blame a surge in whale strandings on the growth of offshore energy projects......»»

Category: topSource:  physorgRelated NewsOct 11th, 2024

High-resolution structural data shows how a supercomplex links mRNA translation and decay

Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena Conti and her team at the Max Planck Institute of Biochemistry in Martinsried near Munich have now been able to show that the.....»»

Category: topSource:  informationweekRelated NewsOct 10th, 2024

How the "social cost of carbon" measurement can hide economic inequalities and mask climate suffering

The social cost of carbon (SCC) is an essential tool for climate decision-making around the world. SCC is essentially a large cost-benefit calculation that helps policymakers compare the benefits of reducing carbon dioxide (CO2) emissions to the soci.....»»

Category: topSource:  physorgRelated NewsOct 10th, 2024

Internet Archive data breach exposes 31M users; under DDoS attack

An Internet Archive data breach has been confirmed by the organisation, which has also been suffering Distributed Denial-of-Service (DDoS) attacks. The home of the Wayback Machine was previously attacked back in May. At this point, it’s being su.....»»

Category: topSource:  informationweekRelated NewsOct 10th, 2024

Nobel chemistry winner sees engineered proteins solving tough problems

Whether it's battling tumors or breaking down plastic, American scientist David Baker, co-recipient of this year's Nobel Prize in Chemistry, has an answer: engineering proteins that don't naturally exist—a concept once dismissed as "crazy.".....»»

Category: topSource:  physorgRelated NewsOct 10th, 2024

Report: M4 iPad Pro demand drops significantly, price might be to blame

The M4 iPad Pro debuted earlier this year with impressive feature upgrades—and higher prices than ever before. According to a new report, demand for the Pro models has dropped significantly, and those premium prices may be to blame. more….....»»

Category: topSource:  informationweekRelated NewsOct 9th, 2024

Nobel Prize in chemistry awarded to 3 scientists for work on proteins, building blocks of life

The Nobel Prize in chemistry was awarded Wednesday to three scientists for their breakthrough work predicting and even designing the structure of proteins, the building blocks of life......»»

Category: topSource:  physorgRelated NewsOct 9th, 2024

Nobel Prize in chemistry awarded for work on proteins

The Nobel Prize in chemistry was awarded Wednesday to scientists David Baker, Demis Hassabis and John Jumper for their work with proteins......»»

Category: topSource:  physorgRelated NewsOct 9th, 2024

Nanopore technique shows transport mechanism of chaperone proteins at the single-molecule level

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality......»»

Category: topSource:  physorgRelated NewsOct 8th, 2024

AI and quantum mechanics team up to accelerate drug discovery

Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects. That requirement for a meticulous fit means the creation of new dr.....»»

Category: topSource:  physorgRelated NewsOct 7th, 2024

Study identifies compounds that extend longevity of Japanese morning glory flowers

The longevity of plant flowers is controlled by genetically programmed mechanisms. After a certain amount of time after flowering, the expression of genes associated with programmed cell death is induced and cellular components such as proteins and n.....»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Ancient protein structure may have enabled early molecular evolution and diversification

In a finding that offers fresh insights into the early evolution of life on Earth, two RIKEN biologists have conducted lab experiments that have revealed a previously unknown protein fold, which is completely absent in modern proteins......»»

Category: topSource:  physorgRelated NewsOct 3rd, 2024

Filament structure found to activate and regulate CRISPR-Cas "protein scissors"

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, al.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

New triple star system sets shortest orbital period record

Professional and amateur astronomers have made a groundbreaking discovery with the help of artificial intelligence, identifying a unique triple star system named TIC 290061484. This stellar trio was uncovered through cosmic "strobe lights" observed b.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024

Developing novel chiral capsule tools for advanced optical technologies

Chirality is an essential property in biology; the molecular building blocks of some of the most important biological structures, including DNA and proteins, are chiral. When a molecule is said to be chiral, it means that it is distinguishable from i.....»»

Category: topSource:  physorgRelated NewsOct 2nd, 2024