Structure-destabilizing mutations transform Bcl-2 from an antiapoptotic protein into a proapoptotic protein
Bcl-2 family proteins are highly conserved molecules that play a crucial role in regulating the release of apoptotic proteins from mitochondria. They possess Bcl-2 homology (BH) domains, which are characterized by both sequence and structural similar.....»»
Imaging advance creates clearer picture of organic solar cells" molecular structure
Research on organic solar cells has been conducted for a long time. Recent advancements in understanding their molecular structures are now paving the way for the development of highly efficient solar cells......»»
Mathematical model decodes protein interactions to show how condensates form
Biological cells are incredibly complex mixes of proteins, nucleic acids, lipids and carbohydrates. A model developed by two RIKEN researchers helps explain why components of the same type sometimes do and sometimes don't spontaneously come together.....»»
Porous nanofibrous microspheres show promise for diabetic wound treatment
Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed a revolutionary injectable granular filler that could transform the way diabetic wounds are treated, potentially improving patient outcomes. The study, published in.....»»
Deep learning enhances accuracy and efficiency in protein structure prediction
In the rapidly advancing field of computational biology, a review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction. The review, published in MedComm—Future Medicine, is led by Dr. Xi Yu an.....»»
Advanced graphics processing units lead to unprecedented speed for electronic structure calculations
A recent collaboration among researchers from HUN-REN Wigner Research Center for Physics in Hungary and the Department of Energy's Pacific Northwest National Laboratory, along with industry collaborators SandboxAQ and NVIDIA, has achieved unprecedent.....»»
Study finds key protein aids nutrient transport within plant cells
Botanists have come to understand the channels and transporters involved in the uptake and transport of nutrients, yet how are they positioned where they need to be?.....»»
“Impact printing” is a cement-free alternative to 3D-printed structures
Impact printing uses a high-velocity jet of material, fusing it into a structure. Recently, construction company ICON announced that it is close to completing the world’s larges.....»»
Antithrombin study proposes new mechanism of action for the plasma protein"s functional role
Antithrombin, a plasma protein, has been reported to control thrombin activity by directly binding to thrombin, as well as to have an anti-inflammatory effect. However, the actual molecular mechanism of the anti-inflammatory effect of antithrombin wa.....»»
Team observes how iron atoms alter grain boundary structures in titanium
Using state-of-the-art microscopy and simulation techniques, an international research team has systematically observed how iron atoms alter the structure of grain boundaries in titanium. Their findings were published in the journal Science on Octobe.....»»
Glycans can regulate their own biosynthesis by modifying enzyme activity
Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics. Glycans can be incredibly complex and branched in structure, contributing to the stability of the extracellular domain of cells and.....»»
Six reasons why people enjoy horror movies
The creeping shadows and haunting decorations transform the everyday into something eerie at Halloween. And you might be thinking about scaring yourself with a good horror movie......»»
Businesses are leveraging the UN Sustainable Development Goals to gain political influence
At first glance, the United Nations' Sustainable Development Goals (SDGs) appear to be a rallying cry for businesses to transform and contribute to the betterment of society and the environment......»»
Discovery of critical iron-transport protein in malaria parasites could lead to faster-acting medications
Malaria kills over 600,000 people a year, and as the climate warms, the potential range of the disease is growing. While some drugs can effectively prevent and treat malaria, resistance to those drugs is also on the rise......»»
Engineered bacterial protein offers efficient rare earth metal separation
A newly discovered protein naturally houses an unusual binding site that can differentiate between rare earth elements, and researchers at Penn State have made it even better. Rare earth elements are key components used in everything from modern tech.....»»
Largest-Ever Pair of Black Hole Jets Stretches 23 Million Light-Years
Supermassive black holes can expel jets of material so vast and powerful that they may shape the large-scale structure of the cosmos.....»»
Researchers discover revolutionary method to rid farm soils of microplastics — here"s how it could transform food supply
Researchers discover revolutionary method to rid farm soils of microplastics — here"s how it could transform food supply.....»»
A Giant Structure in Space Challenges Our Understanding of The Universe
A Giant Structure in Space Challenges Our Understanding of The Universe.....»»
Optical technique that uses orbital angular momentum could transform medical diagnostics
An Aston University researcher has developed a new technique using light that could revolutionize non-invasive medical diagnostics and optical communication. The research showcases how a type of light called the orbital angular momentum (OAM) can be.....»»
Re-analysis of Milky Way"s central supermassive black hole shows elongated structure
A research team led by Assistant Professor Makoto Miyoshi of the National Astronomical Observatory of Japan (NAOJ) has independently re-analyzed observation data of the supermassive black hole at the center of the Milky Way galaxy obtained and publis.....»»
Synthesis method improves catalytic activity by controlling the surface structure of metal particles
Fine-tuning the reactions that produce hydrogen (H2) for use as a clean fuel is an important endeavor to fight against climate change. Researchers at Tohoku University and the Tokyo University of Science have succeeded in improving the catalytic acti.....»»