Structure-destabilizing mutations transform Bcl-2 from an antiapoptotic protein into a proapoptotic protein
Bcl-2 family proteins are highly conserved molecules that play a crucial role in regulating the release of apoptotic proteins from mitochondria. They possess Bcl-2 homology (BH) domains, which are characterized by both sequence and structural similar.....»»
Mathematical approach can predict crystal structure in hours instead of months
Researchers at New York University have devised a mathematical approach to predict the structures of crystals—a critical step in developing many medicines and electronic devices—in a matter of hours using only a laptop, a process that previously.....»»
Scientists engineer stable protein complexes for targeted cancer therapies
Researchers from Auburn University, partnering with the University of Basel in Switzerland, have discovered a new way to make a cancer-targeting protein complex more stable, opening doors to better cancer treatments. Led by Dr. Rafael Bernardi from A.....»»
Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
Q&A: Holobiont biology, a new concept for exploring how microbiome shapes evolution of visible life
Microorganisms—bacteria, viruses and other tiny life forms—may drive biological variation in visible life as much, if not more, than genetic mutations, creating new lineages and even new species of animals and plants, according to Seth Bordenstei.....»»
Rue Valley puts a time loop spin on Disco Elysium
Rue Valley is the latest video game to utilize a time loop hook, applying that structure to a Disco Elysium-like RPG......»»
A new vertical seed distribution trait for soybean breeding
As the human population increases and protein demand doubles, modern plant breeders must further optimize soybean plant architecture and per plant yield for modern farming systems......»»
Seaweed proteins could be the next sustainable food source
The protein in sea lettuce, a type of seaweed, is a promising complement to both meat and other current alternative protein sources. Seaweed also contains many other important nutrients, and is grown without needing to be watered, fertilized or spray.....»»
Laser spectroscopy study explores nuclear structure of fermium and nobelium isotopes
University of Liverpool researchers are part of an international research collaboration that has shed light on what happens at the extremes of neutron and proton numbers, in search of where the periodic table of chemical elements ends......»»
How to start using Image Playground in iOS 18.2 to create funny selfies
Transform your iPhone 16 into a digital art studio with iOS 18.2's Image Playground, the latest tool for creating custom visuals with a few taps.Ninja the cat moves through the house unseenWith the release of iOS 18.2, Apple's Image Playground app of.....»»
Plastics pollution worsens the impacts of all planetary boundaries, new study says
Plastics are not as safe and inert as previously thought. A new research study written by an international team of researchers uses the planetary boundaries framework to structure the rapidly mounting evidence of the effects of plastics on the enviro.....»»
New report sets out a route to transform environmental consenting in UK offshore wind
A report published this week by the Offshore Renewable Energy (ORE) Catapult lays out a new approach to environmental monitoring and consenting within the UK offshore wind sector......»»
Astronomers use JWST and ALMA to explore the structure of a giant spiral galaxy
Using the James Webb Space Telescope (JWST) and the Atacama Large Millimeter/submillimeter Array (ALMA), an international team of astronomers have observed a giant spiral galaxy designated ADF22.A1. Results of the observational campaign, published Oc.....»»
Scientists use high-energy heavy ion collisions as a new tool to reveal subtleties of nuclear structure
Scientists have demonstrated a new way to use high-energy particle smashups at the Relativistic Heavy Ion Collider (RHIC)—a U.S. Department of Energy (DOE) Office of Science user facility for nuclear physics research at DOE's Brookhaven National La.....»»
Controlling skyrmions at room-temperature in 2D topological spin structure technology
The Korea Research Institute of Standards and Science (KRISS) has, for the first time in the world, generated and controlled skyrmions at room temperature in two-dimensional (2D) materials. This achievement reduces power consumption compared to tradi.....»»
Novel flame aerosol system excels at creating nanoparticles
Since prehistoric times, humans have used fire to transform raw materials into valuable goods. Examples include using flames to turn clay into pottery, and silica into glass......»»
Beta cells: New insights into the structure, interactions and neuronal networking of primary cilia
Dysfunctions of the tiny cell processes (primary cilia) of the pancreatic beta cells could be a cause of type 2 diabetes. Little is known about the structure and function of these cilia. An international research team led by DZD researchers from the.....»»
Sequencing one of the world"s oldest trees to learn how mutations occur in clonally reproducing organisms
A team of biologists, environmental scientists and geneticists affiliated with multiple institutions across the U.S. has learned more about how mutations occur in clonally reproducing organisms by sequencing one of the oldest trees in the world. The.....»»
The Virus That Causes Mpox Keeps Getting Better at Spreading in People
Analysis of a strain of the virus circulating in Central Africa shows genetic mutations indicative of sustained human-to-human spread.....»»
Massive fire closes Ohio River bridge near Cincinnati and damages its steel structure
Massive fire closes Ohio River bridge near Cincinnati and damages its steel structure.....»»
Biotech approach enhances nutritional value of black soldier fly larvae
With the rapid increase in the global population, a "protein crisis" is expected in the near future, where the supply of protein will not be able to meet the rising demand......»»