Structure-destabilizing mutations transform Bcl-2 from an antiapoptotic protein into a proapoptotic protein
Bcl-2 family proteins are highly conserved molecules that play a crucial role in regulating the release of apoptotic proteins from mitochondria. They possess Bcl-2 homology (BH) domains, which are characterized by both sequence and structural similar.....»»
Polymer foam aims to transform oil spill cleanup
University of Waterloo researchers have developed a new material that can absorb more than eight times its weight in oil, offering a new solution in preventing groundwater contamination from spills or accidents. The study, "Fabrication of Triblock El.....»»
Bioengineers develop protein assembly road map for nature-derived nanobubbles
As far as water gear goes, floaties are not exactly high tech. But the tiny air-filled bubbles some microorganisms use as flotation devices when they compete for light on the water surface are a different story......»»
Breaking boundaries: PAM-less genome editing in soybean
CRISPR-Cas9 has transformed crop genetic improvement, yet its reliance on specific protospacer adjacent motif (PAM), sequences limits editing scope and efficiency. In soybean, a critical source of protein and oil, these limitations hinder the develop.....»»
Color-changing, self-healing hydrogel microparticles: A smart solution for advanced wound care
Chronic diabetic wounds are prevalent in patients and are difficult to heal, presenting a significant medical challenge. The development of multifunctional hydrogel dressings with a well-designed morphology and structure can enhance their flexibility.....»»
The ShiftCam SnapSeries will turn your phone into the ultimate vlogging machine
Want to transform your smartphone into the ultimate vlogging tool? The new ShiftCam SnapSeries is for you......»»
Seismic echoes reveal a mysterious "donut" inside Earth"s core
About 2,890 kilometers beneath our feet lies a gigantic ball of liquid metal: our planet's core. Scientists like me use the seismic waves created by earthquakes as a kind of ultrasound to "see" the shape and structure of the core......»»
New discovery of how bacteria navigate their environment could change how we treat infection
Scientists from the University of Sheffield have discovered a new sensory capability in bacteria which could transform treatments for bacterial infections......»»
Investigation reveals global fisheries are in far worse shape than we thought—and many have already collapsed
When fish are taken from our oceans faster than they can reproduce, their population numbers decline. This over-fishing upsets marine ecosystems. It's also bad for human populations that rely on fish for protein in their diets......»»
Researchers identify genes for low glycemic index and high protein in rice
A team of researchers at the International Rice Research Institute (IRRI) has identified genes and markers responsible for low glycemic index (GI) and high protein content in rice, using genetics and artificial intelligence classification methods......»»
Advances in optical micronanofiber-enabled tactile sensors and soft actuators
A perfect combination of fiber optics and micro/nanotechnology, optical micro/nanofiber (MNF) is a new type of micro/nano-waveguide structure developed in recent years......»»
Scientists unlock the secrets of how a key protein converts DNA into RNA
Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»
Exploring functional organic materials for the energy transition
Carbon, of all things, could help us to push forward the decarbonization of our industrial society. Functional carbon particles, known as carbon dots, can transform sunlight into energy and extract hydrogen from water. Prof. Dr. Dirk M. Guldi, a chem.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Study shows an electrically-activated protein regulates spermatogenesis
Frankenstein's monster was brought to life by the judicious application of a little electricity; and a surprising number of processes in our bodies are regulated by electrical currents too. Now, researchers from Japan reveal that electricity may play.....»»
Study finds flexibility and helical twists of actin filaments regulate actin-binding proteins
Researchers at Kanazawa University have published an article in eLife deciphering the actin structure-dependent preferential cooperative binding of cofilin......»»
"Silent" mutations found to have repercussions beyond their own gene
Genetic disorders—like cystic fibrosis and Huntington's disease—are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one nucleotide in a codon is switched. In non-synonymous muta.....»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Generalized splitting-ring number theoretic transform
Number theoretic transform (NTT) is widely recognized as the most efficient method for computing polynomial multiplication with high dimension and integral coefficients, due to its quasilinear complexity......»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»