SPNS2 found to be directly exporting S1P for signaling, can be inhibited
When an enemy invades, defenders are ferried to the site to neutralize the marauders. In the human body, a protein carrier called SPNS2 transports S1P molecules from endothelial cells to rally immune cell response in infected organs and tissues......»»
Stellantis cuts costs rather than turn defensive as Chinese threat grows
CEO Carlos Tavares said Stellantis would stick to its "asset light" strategy in China, mainly focused on exporting to the country rather than manufacturing there. .....»»
Scientists discover non-transcriptional mechanism of karrikin signaling transduction
Researchers led by Dr. Wang Lei and Wang Bing from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have shown that the non-transcriptional activity of the transcriptional repressor proteins SUPPRESSOR OF MAX2 1.....»»
A protein that enables smell in ants—and stops cell death
While smell plays a considerable role in the social interactions of humans—for instance, signaling fear or generating closeness—for ants, it is vitally important. Researchers from New York University and the University of Florida found that a key.....»»
Enhancing forest productivity through improved phosphorus use
A research team has reviewed the mechanisms of inorganic phosphorus (Pi) uptake, transport, and signaling in woody plants based on the backbone of model and crop plants. Their findings emphasize the importance of Pi in photosynthesis, respiration, an.....»»
Maybe Google hasn’t given up on Google Glass after all
Google just partnered with a leading AR glasses manufacturer, signaling that Google Glass could return with the most advanced technology available......»»
Apple may label iOS 18 artificial intelligence features as a beta preview, signaling Apple is still playing catch-up
In the latest edition of Mark Gurman’s newsletter for Bloomberg, he reports that Apple’s highly-anticipated AI features for iOS 18 and its other operating systems may be released with a ‘beta’ or ‘preview’ designation. This is perhaps.....»»
Repurposed protease controls important signaling molecule-activating protein
Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease. The rapid release of at least 80 signaling molecules, including tumor necrosis factor and epidermal growth factor, is con.....»»
Study demonstrate improved root growth in radio-cesium contaminated soil
Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) have identified a way for plants to gain resistance to cesium, a radioactive toxin that can be found in contaminated soil. After manipulating a specific biological signaling path.....»»
A systematic review of three key sugar metabolism proteins: HXK, SnRK1 and TOR
Sugar signaling is one of the most important regulatory signals for plant growth and development, and its metabolic network contains many regulatory factors. Sugar signaling molecules regulate cellular activities and organismal development by interac.....»»
Molecular mechanism of CmoDREB2A and CmoNAC1 in pumpkin regulating the salt tolerance of grafted cucumber revealed
In February 2024, a research article titled "Pumpkin CmoDREB2A enhances salt tolerance of grafted cucumber through interaction with CmoNAC1 to regulate H2O2 and ABA signaling and K+/Na+ homeostasis" was published by Professor Zhilong Bie's team from.....»»
Microsoft’s Phi-3 shows the surprising power of small, locally run AI language models
Microsoft’s 3.8B parameter Phi-3 may rival GPT-3.5, signaling a new era of “small language models." Enlarge (credit: Getty Images) On Tuesday, Microsoft announced a new, freely available lightweight AI language model.....»»
The role of TOR signaling in enhancing graft success and crop vigor
A research team has delved into the Target of Rapamycin (TOR) signaling pathway in plant grafting, emphasizing its role in regulating seedling vigor, graft junction healing, and shoot-to-root communications. Exploring TOR's involvement offers a promi.....»»
New signaling pathway decoded in the decomposition of damaged lysosomes
Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can trigger inflammation a.....»»
Security pros are cautiously optimistic about AI
55% of organizations plan to adopt GenAI solutions within this year, signaling a substantial surge in GenAI integration, according to a Cloud Security Alliance and Google Cloud survey. The survey received 2,486 responses from IT and security professi.....»»
New study paves the way for precision drugs to treat blood cancers
The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent signaling and under.....»»
Apple’s new Beats Solo 4 headphones hit the FCC ahead of launch
In February, images of unreleased Beats Solo 4 headphones were revealed thanks to the iOS 17.4 beta. Now, the Beats Solo 4 have popped up in the FCC’s database, signaling that a launch is imminent. They’ll mark the first update to the Beats Solo.....»»
Gene editing technology reveals molecular mechanisms governing diatom population density signals
The intricate dynamics of diatom blooms, influenced by a myriad of external factors and internal signals, continue to fascinate scientists. After recognizing the potential role of density perception and intracellular signaling in dictating these phen.....»»
Scientists identify novel lysosome fission factor
Lysosomes are centers for degradation, recycling, and signaling of cellular materials that are crucial for maintaining cellular homeostasis, development, and aging. To meet various physiological demands, lysosomes continuously remodel their shape and.....»»
Enhancing apple adventitious shoot regeneration: The role of MdAIL5 in hormonal signaling and gene activation
Plants exhibit a remarkable capacity for self-repair and regeneration, a process crucial for adapting to environmental changes and underpinned by cellular totipotency or pluripotency. Apple is one of the model plants for the study of perennial woody.....»»
Secure email gateways struggle to keep pace with sophisticated phishing campaigns
In 2023, malicious email threats bypassing secure email gateways (SEGs) increased by more than 100%, according to Cofense. In just two years, Cofense identified over 1.5 million malicious emails bypassing their customers’ SEGs, signaling a 37% incr.....»»