Self-regulation of an enzyme with critical cellular functions
The lab of Kathy Gould, Louise B. McGavock Professor and professor of cell and developmental biology, used a multi-disciplinary approach that included structural biology, biochemistry, and molecular biology to investigate the regulation of the CK1 en.....»»
Gambling marketing and the Premier League—the continued failure of industry self-regulation
New research reveals gambling messages during the opening weekend of this season's football Premier League have almost trebled since last year, putting fans including children at risk......»»
Trimer complex TaNF-Y balances grain yield and quality in wheat: Study
Breeding efforts have focused intensively on improving grain yield and quality in wheat (Triticum aestivum L.). Content and composition of grain starch and seed storage protein (SSP) are two critical factors that determine grain yield and quality. St.....»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
Scientists uncover a critical component that helps killifish regenerate their fins
Spontaneous injuries like the loss of a limb or damage to the spinal cord are impossible for humans to repair. Yet, some animals have an extraordinary capacity to regenerate after injury, a response that requires a precise sequence of cellular events.....»»
Scientists develop method to control timing of synthetic DNA droplet division
Many cellular functions in the human body are controlled by biological droplets called liquid-liquid phase separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside living cells but are not enclosed by membranes like.....»»
Researchers explore novel approach to map forest dieback in satellite images
Forests and woodlands cover one third of Earth's surface and play a critical role in carbon sequestration, water regulation, timber production, soil protection, and biodiversity conservation. Accelerated by climate change, the decline of these and ot.....»»
"Writing" with atoms could transform materials fabrication for quantum devices
A new technology to continuously place individual atoms exactly where they are needed could lead to new materials for devices that address critical needs for the field of quantum computing and communication that cannot be produced by conventional mea.....»»
Neutron experiments settle 40-year debate on enzyme for drug design
In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers......»»
KELA Identity Guard detects and intercepts compromised assets
KELA launched Identity Guard, the first line of defense to help combat the #1 cause of data breaches – compromised corporate assets and identities. Identity Guard is a critical module of KELA’s threat intelligence platform, already in use.....»»
MFA bypass becomes a critical security issue as ransomware tactics advance
Ransomware is seen as the biggest cybersecurity threat across every industry, with 75% of organizations affected by ransomware more than once in the past 12 months – a jump from 61% in 2023, according to SpyCloud. Session hijacking surges as ma.....»»
Sharks and rays leap out of the water for many reasons, including feeding, courtship and communication
Many sharks and rays are known to breach, leaping fully or partly out of the water. In a recent study, colleagues and I reviewed research on breaching and ranked the most commonly hypothesized functions for it......»»
American Honda aims to increase CPO leasing mix
The automaker will continue to enhance its leasing programs for used vehicles, a "critical gateway" for young and first-time buyers......»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
Paid open-source maintainers spend more time on security
Paid maintainers are 55% more likely to implement critical security and maintenance practices than unpaid maintainers and are dedicating more time to implementing security practices like those included in industry standards like the OpenSSF Scorecard.....»»
Week in review: Critical VMware vCenter Server bugs fixed, Apple releases iOS 18
Here’s an overview of some of last week’s most interesting news, articles, interviews and videos: Critical VMware vCenter Server bugs fixed (CVE-2024-38812) Broadcom has released fixes for two vulnerabilities affecting VMware vCenter Server that.....»»
Apple @ Work: It’s time for Apple to add cellular to the Mac
Apple @ Work is exclusively brought to you by Mosyle, the only Apple Unified Platform. Mosyle is the only solution that integrates in a single professional-grade platform all the solutions necessary to seamlessly and automatically deploy, manage & pr.....»»
AI tools help uncover enzyme mechanisms for lasso peptides
Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tes.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
Recharging mitochondria—nanoflowers offer a new way to simulate energy production to improve aging ailments
When we need to recharge, we might take a vacation or relax at the spa. But what if we could recharge at the cellular level, fighting against aging and disease with the microscopic building blocks that make up the human body?.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»