SARS-CoV-2: Neutralization of BA.1 and BA.2 by therapeutic monoclonal antibodies
Scientists studied the sensitivity of Omicron BA.1 and BA.2 to nine monoclonal antibodies, some of which are used in pre-exposure prophylaxis in immunocompromised individuals. The scientists showed a loss of neutralizing activity against BA.1 and BA......»»
Crucial early-warning listserv for tracking disease outbreaks is in danger
ProMED, which broke news of COVID, SARS, and MERS, is short on cash and in turmoil. Enlarge (credit: Miragec/Getty Images) Internal dissent within the mostly volunteer disease-news network known as ProMED—which alerted.....»»
New SARS-CoV-2 variant gains dominance in US amid mild summer COVID wave
Absolute numbers are low, but several indicators show pandemic virus is on the rise. Enlarge (credit: Getty | Thomas Trutschel) For a fourth consecutive summer, COVID-19 is on the rise, though this year's warm-weather wa.....»»
A Crucial Early Warning System for Disease Outbreaks Is in Jeopardy
The ProMED website and listserv, which broke the news of the arrival of Covid, SARS, and MERS, is now caught between financial shortfalls and staff turmoil......»»
Deepfence ThreatStryker offers runtime protection and inline threat neutralization
Deepfence released ThreatStryker, an enterprise offering built on top of ThreatMapper. “Deepfence has changed the economic landscape of cloud security with our open source first strategy which insists that companies shouldn’t have to pay.....»»
Novel nano-immune magnetic bead may provide faster way to catch SARS-CoV-2
A more efficient way to test SARS-CoV-2 virus was developed recently by a research team led by Professor Wang Junfeng from Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Science (CAS). The novel nano-immune magnetic bead (Mal-IMB) t.....»»
Researchers use X-rays to find the best antibodies
Antibody therapies have a variety of uses, but we need to know which therapies work and which ones don't. Recent research has discovered a means to determine how effective certain antibodies can be in medical scenarios......»»
Research shows that genetically engineered vesicles better target cancer cells
Two unfortunate facts about chemotherapy: It can harm healthy cells as well as cancerous ones, and many therapeutic targets stay within cancer cells, making them harder to reach......»»
New infection mechanism in SARS-CoV-2 discovered
Researchers from Heidelberg Medical Faculty, Heidelberg University Hospital and German Cancer Research Center investigate molecular relationships that promote infection and spread of SARS-CoV-2. The results may provide a starting point for developmen.....»»
Study discovers novel region for BRD4 transcription and potential therapeutic target
A team of investigators in the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a novel protein region responsible for regulating DNA transcription elongati.....»»
Development of new p38 protein inhibitors with therapeutic potential for some heart diseases
The p38 protein regulates a wide variety of cellular functions and is related to diseases such as chronic inflammation, immunological disorders, or cancer. To date, it has been difficult to find p38 inhibitors for use in clinical practice because the.....»»
WildDISCO: Visualizing whole bodies in unprecedented detail
Researchers developed a new method called wildDISCO that uses standard antibodies to map the entire body of an animal using fluorescent markers. This revolutionary technique provides detailed 3D maps of structures, shedding new light on complex biolo.....»»
Newly-identified compound inhibits SARS-CoV-2 by targeting the nucleocapsid protein
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally since 2020. The nucleocapsid (N) protein plays a crucial role in the life cycle of SARS-CoV-2......»»
Team develops all-species coronavirus test
In an advance that will help scientists track coronavirus variants in wild and domesticated animals, researchers report they can now detect exposure to the SARS-CoV-2 virus in any animal species. Most coronavirus antibody tests require specialized ch.....»»
Transplantation of genome-edited iPS cells delivers therapeutic molecules in vivo
Induced pluripotent stem (iPS) cells have a great impact on biology and medicine, and they are expected to improve regenerative medicine. Since 2014, when a sheet of retinal pigment epithelial cells derived from iPS cells was transplanted into patien.....»»
New pathway discovered for RNA degradation in iron-rich environments
RNA, an essential biomolecule for life, has been used in environmental applications including monitoring microbial communities, developing pesticides, and quantifying the abundance of pathogenic viruses, such as SARS-CoV-2, in water and wastewater sy.....»»
Biolab replaces horseradish roots for production of important enzymes
It is one of the most important enzymes in medical diagnostics: Horseradish peroxidase is used for many medical products—it is often used when a color change of a test strip is to detect the presence of antibodies or other proteins......»»
Researchers develop first-of-its-kind adhesive bandage that uses gold nanoparticles to detect COVID-19 antibodies
Researchers at NYU Abu Dhabi have developed a new rapid testing method for COVID-19—an adhesive bandage that relies on gold nanoparticles to quickly detect the immune antibodies in the bloodstream......»»
Researchers identify a protein as a potential therapeutic target for age-related diseases
A research team from the Hong Kong University of Science and Technology (HKUST) has identified a key protein that may shed light on how to reverse the aging process using the adult stem cell of skeletal muscle (or muscle stem cells, MuSCs) as a model.....»»
Coronavirus only needs to bind to a single receptor, shows study
Why is the SARS-CoV-2 coronavirus able to spread so efficiently? Various hypotheses are still circulating in the scientific community. A group of researchers from Würzburg has now found new answers......»»
Team develops magnetic microrobots with folate to promote targeted drug delivery to cancer cells
The limited ability of microrobots to assist drugs in entering cells hinders their therapeutic efficacy. To address this, a research team, reporting in Cyborg and Bionic Systems, has introduced the cancer-targeting molecule folic acid (FA) to microro.....»»