RNA modification: Mechanisms and therapeutic targets
RNA modifications are dynamic and reversible chemical modifications on substrate RNA that regulate mRNA stability, translation, and localization. This review is designed by Dr. Junhong Han and written by his postdoctoral researcher Dr. Lei Qiu and P.....»»
From bands to spots, the secrets of the leopard gecko"s skin
While the patterns and colors of lizards' skin are fascinating, the mechanisms behind them are largely unknown. A team from the University of Geneva (UNIGE) studied the leopard gecko, a popular lizard, to understand how the bands on the skin of juven.....»»
Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease
Allogenic hematopoietic cell transplantation (allo-HCT) involves transferring healthy donor stem cells to recipients with conditions such as blood cancer, bone marrow failure, or certain genetic blood disorders. Acute graft-versus-host disease (aGVHD.....»»
NHTSA opens recall query into about 94,000 Jeep Wrangler 4xe SUVs
The investigation targets Jeep's Wrangler 4xe hybrid SUVs manufactured between 2021 through 2024. Chrysler had previously recalled the same model in 2022 to address concerns related to an engine shutdown......»»
Intracellular mechanisms shown to promote spread of deadly bacterial infection
Northwestern Medicine investigators have discovered novel protein mechanisms that promote the rapid spread of Vibrio vulnificus, a rare but lethal bacteria that can cause vibriosis and sepsis, according to findings published in the Proceedings of the.....»»
Spot delivery lawsuit targets Conn. Chevrolet dealership
A Connecticut dealership initially told a customer his credit application was approved and gave him the vehicle in a spot delivery, only to later inform him his credit was denied and demand that he return of the car......»»
Researchers explain the imaging mechanisms of atomic force microscopy in 3D
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report the 3D imaging of a suspended nanostructure. The technique used is an extension of atomic force microscopy and is a promising approach for visualizing various 3D bio.....»»
The influence of peptoid sequence on the mechanisms and kinetics of 2D assembly
Two-dimensional (2D) materials have unique physical and chemical properties and potential for a wide variety of applications. Peptoids, a type of molecule, compose a class of sequence-defined polymers that mimic biological compounds and can self-asse.....»»
Researchers uncover key mechanisms in chromosome structure development
Researchers at Rice University are making strides in understanding how chromosome structures change throughout the cell's life cycle. Their study on motorized processes that actively influence the organization of chromosomes appears in the Proceeding.....»»
New theory reveals fracture mechanism in soft materials
A new theory has finally deciphered the physical mechanisms of fracture in soft materials. This discovery could soon lead to new, defect-free materials that are more resistant and durable as well as environmentally friendly. The article "Elastic inst.....»»
Study highlights tension between Canada"s climate and housing goals
Canada cannot simultaneously meet its targets for emission reductions and new housing unless there's a drastic change in construction practices, according to research from the University of Toronto's Faculty of Applied Science & Engineering......»»
New mRNA technology turns cells into long-lasting drug factories
A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body,.....»»
Honest dialogue is needed to help build consensus around solar radiation modification technology
Solar Radiation Modification (SRM) is a suite of possible technologies to counteract global warming by reflecting incoming solar radiation......»»
NYT targets Street View Worldle game in fight to wipe out Wordle clones
Worldle creator surprised by fight, refuses to bow to NYT. Enlarge (credit: NurPhoto / Contributor | NurPhoto) The New York Times is fighting to take down a game called Worldle, according to a legal filing viewed by the.....»»
Jeep targets Tesla Model Y buyers with Wagoneer S EV
Jeep's first EV for the U.S. and Canada has an estimated range of more than 300 miles and a 0-to-60 mph time of 3.4 seconds......»»
Simulations demonstrate potential mechanisms of intermediate-mass black hole formation in globular clusters
Joint research led by Michiko Fujii of the University of Tokyo demonstrates a possible formation mechanism of intermediate-mass black holes in globular clusters, star clusters that could contain tens of thousands or even millions of tightly packed st.....»»
A risky path to meeting climate targets for Stockholm
The Swedish capital Stockholm aims to capture more carbon dioxide than is emitted by 2030. Therefore, the city is investing in new technology at a combined heat and power plant. But it is a strategy that has been adopted without sufficient discussion.....»»
Researchers unveil the mechanisms for local amplification of 2024 tsunamis in Iida Bay, Japan
In 2024, a 7.5 magnitude earthquake struck the Noto Peninsula in Japan on New Year's Day, causing strong shaking, landslides, fire, liquefaction, land uplift, and devastating tsunamis. Ishikawa Prefecture, the hardest hit area, saw at least 241 fatal.....»»
Research suggests hate speech experiences drop when schools offer structure and adult support
Asian Americans have been the targets of hate speech for generations, particularly during the COVID pandemic. But new research by the University of California, Davis, suggests that Asian American adolescents experience fewer incidents of hate speech.....»»
From leaf to cup: Decoding the biochemical dance of black tea"s fragrance
The journey from tea leaf to infusion is a complex one, with a multitude of factors influencing the final taste and aroma. Despite its importance, the precise biochemical mechanisms at play have been shrouded in mystery. Addressing this knowledge gap.....»»
Black holes are firing beams of particles, changing targets over time
Black holes seem to provide endless fascination to astronomers. This is at least partly due to the extreme physics that takes place in and around them, but sometimes, it might harken back to cultural touchpoints that made them interested in astronomy.....»»