RNA modification: Mechanisms and therapeutic targets
RNA modifications are dynamic and reversible chemical modifications on substrate RNA that regulate mRNA stability, translation, and localization. This review is designed by Dr. Junhong Han and written by his postdoctoral researcher Dr. Lei Qiu and P.....»»
Methane is pitched as a climate villain—could changing how we think about it make it a savior?
Surging methane emissions put our ability to meet Paris agreement climate targets in jeopardy. But a timely new book presents the scientific, policy and technological challenges and solutions for achieving rapid climate gains by addressing this once.....»»
Greenhouse gains: Cucumbers genetic upgrade through innovative pollen tech
Genetic modification in horticultural crops, particularly within the Cucurbitaceae family, is often hindered by complex tissue culture requirements and environmental pressures such as climate change. Traditional transformation techniques, like Agroba.....»»
Scientists find new epigenetic switch, revealing how genes are regulated in early development
The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early emb.....»»
An unexpected protein connection in maize growth and defense could enhance crop resilience
Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored......»»
German maker of digital price tag tech targets U.S. dealers
Digital Communication Solutions developed digital price tag tech that relies in part on artificial intelligence. Prices can be changed instantly......»»
Researchers develop new method for delivering RNA and drugs into cells
Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA and potent drugs directly into cells, potentially leading to a more effective treatment of diseases......»»
Virtual laboratory allows scientists to simulate specific decreases in gene activity
Imagine you're looking at millions upon millions of mysterious genetic mutations. With CRISPR gene-editing technology, a select few of these mutations might have therapeutic potential. However, proving it would mean many thousands of hours of lab wor.....»»
Future foods: How non-thermal tech could transform starch consumption
Starch is a vital component of the human diet, serving as a primary energy source. However, high-glycemic starches are linked to the increasing prevalence of chronic diseases like obesity and diabetes. Traditional starch modification methods, such as.....»»
Amazon’s Shipping and Delivery Emissions Just Keep Going Up
A new report attempts to calculate how much damage shipping our Amazon orders is doing to the planet and how badly the company is missing its own targets......»»
Human "molecular map" contributes to the understanding of disease mechanisms
Scientists at Weill Cornell Medicine in Qatar (WCM-Q) have created an intricate molecular map of the human body and its complex physiological processes based on the analysis of thousands of molecules in blood, urine and saliva samples from 391 volunt.....»»
Study links EV charging stations to increased local business activity
Countries globally are rapidly transitioning to a cleaner energy future—accelerating their push for electric vehicles alongside ambitious targets to phase out gasoline and diesel in transportation. Global electric car sales surged by around 25% in.....»»
Researchers reveal the mechanisms behind cobalt X-ide electrocatalysts
The unsung heroes of electrochemical reactions—electrocatalysts—can assist in optimizing factors such as the reaction's speed, yield, and energy consumption. As such, these electrocatalysts are crucial for optimizing large-scale production in the.....»»
Unlocking plant defense: Bacterial hijacking exposed
Bacterial wilt caused by Ralstonia solanacearum poses a severe threat to agriculture worldwide, affecting numerous crops. The pathogen's arsenal of type III effectors (T3Es) enables it to manipulate host defense mechanisms, aiding infection. One majo.....»»
Uncovering the unique roles of Exportin-5 in RNA export within Drosophila cells
Eukaryotic cells are complex biological units, each with multiple membrane-bound compartments. These cells use specialized mechanisms to export biomolecules from their synthesis site to where they function......»»
How well are NZ companies reporting their climate impacts? A new tracker shows very mixed results
Interpreting corporate reports on carbon emissions can be challenging. The current, adhoc approach to how businesses share this information makes it difficult to see whether they have set the right targets, have realistic plans to meet them or are be.....»»
Why do materials get stronger when they are deformed? Research sheds light on universal mechanisms of work hardening
The earliest blacksmiths in the Bronze and Iron Ages figured out that when they deformed metal through bending or hammering, it became stronger. This process, known as work or strain hardening, is still used widely in metallurgy and manufacturing tod.....»»
Solving the side effect problem of siRNA drugs for genetic disease treatment
Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence genes other than the target ones, causing side eff.....»»
Researchers develop molecular biosensors that only light up upon binding to their targets
Biosensors—devices that use biological molecules to detect the presence of a target substance—have enormous potential for detecting disease biomarkers, molecules-in-action in diverse biological processes, or toxins and other harmful substances in.....»»
Bitdefender Security for Creators protects YouTube content creators and influencers from hackers
Bitdefender unveiled Bitdefender Security for Creators, a service specifically designed for digital content producers, online creative professionals and social media influencers who are prime targets for account takeovers, fraud, and other cybercrime.....»»
North Korean hackers’ social engineering tricks
“North Korean malicious cyber actors conducted research on a variety of targets connected to cryptocurrency exchange-traded funds (ETFs) over the last several months,” the FBI has warned through a public service announcement. This suggest.....»»