Regulator proteins or symphonies of genes: Statistical modeling points way toward unified theory for DNA folding
At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining the.....»»
Planning a drug"s route in the body with synthetic chemistry
Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins......»»
Are plants and fungi trading carbon for nutrients? Not likely, say researchers
Every year, plants move 3.58 gigatons of carbon to mycorrhizal fungi, their underground partners—enough, in fact, that if it were ice, it would cover 112 million NHL hockey rinks. However, a dominant scientific theory explaining that huge transfer.....»»
Farmer sentiment reaches lowest levels since 2016 as income expectations weaken
In September, the Purdue University/CME Group Ag Economy Barometer recorded its lowest readings since March 2016. Declining income expectations pushed farmer sentiment down as the barometer fell 12 points to 88, and the Index of Future Expectations.....»»
Research provides new insights into role of mechanical forces in gene expression
The genome inside each of our cells is modeled by tension and torsion—due in part to the activity of proteins that compact, loop, wrap and untwist DNA—but scientists know little about how those forces affect the transcription of genes......»»
High-resolution images of RSV may expose stubborn virus"s weak points
The complex shape of respiratory syncytial virus (RSV) is one hurdle limiting the development of treatments for an infection that leads to hospitalization or worse for hundreds of thousands of people in the United States each year, according to the C.....»»
Seeing double: Designing drugs that target "twin" cancer proteins
Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»
Apple @ Work Podcast: Hacker Rangers
Apple @ Work is exclusively brought to you by Mosyle, the only Apple Unified Platform. Mosyle is the only solution that integrates in a single professional-grade platform all the solutions necessary to seamlessly and automatically deploy, manage & p.....»»
Ancient Peru throne room points to possible female ruler, archaeologists say
Ancient Peru throne room points to possible female ruler, archaeologists say.....»»
Security Bite: Apple pulls dozens of VPN apps from App Store in Russia
9to5Mac Security Bite is exclusively brought to you by Mosyle, the only Apple Unified Platform. Making Apple devices work-ready and enterprise-safe is all we do. Our unique integrated approach to management and security combines state-of-the-art App.....»»
Security Bite: Apple reportedly cooperating with Russia to quietly remove VPN apps from App Store
9to5Mac Security Bite is exclusively brought to you by Mosyle, the only Apple Unified Platform. Making Apple devices work-ready and enterprise-safe is all we do. Our unique integrated approach to management and security combines state-of-the-art App.....»»
Exploring the role of hydrogen sulfide in the expression of iron uptake genes in E. coli
Antibiotic resistance and oxidative stress response are important biological mechanisms that help bacteria thrive, especially pathogenic bacteria like Escherichia coli. Hydrogen sulfide (H2S), a chemical messenger molecule, regulates several intracel.....»»
The biological marvels of the seabed are being mined to create commercial products—here are the risks
Thousands of genes from deep-sea marine life are being used to create new commercial products ranging from pharmaceuticals to cosmetics. Genes are segments of DNA that provide instructions for making other molecules that are essential for the structu.....»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Future climate change predicted to shift flood-generating mechanisms and intensify extreme flooding events
The Delaware River Basin, a coastal watershed in the Mid-Atlantic region, has a long history of severe flooding with significant socioeconomic impacts. Recent research uses a process-based modeling approach to analyze hydrometeorological (like rainfa.....»»
Climate change will lead to wetter US winters, modeling study finds
Most Americans can expect wetter winters in the future due to global warming, according to a new study led by a University of Illinois Chicago scientist......»»
This folding phone does something different, and I love it
The Xiaomi Mix Flip is yet another folding flip phone, but it's quite a bit different from the competition — and I love it. Let me tell you why......»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
A method of "look twice, forgive once" can sustain social cooperation
The theory of indirect reciprocity holds that people who earn a good reputation by helping others are more likely to be rewarded by third parties, but widespread cooperation depends on agreement about reputations......»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
Are tougher political sanctions better? A statistical model compares political and economic relationships to success
Before beginning its war of aggression against Ukraine in 2022, Russia had already conducted an aerial bombardment of Georgia in 2008 and invaded Crimea as well as the Donbas region in 2014. This has left politicians and researchers puzzling over the.....»»