Protein engineers navigate toward more targeted therapeutics
More than a third of FDA-approved drugs work by targeting a G protein-coupled receptor, or GPCR. The human body has more than 800 types of GPCRs that provide cells with information about the external environment to calibrate responses. Drugs that eit.....»»
Areas with more illegal market opportunities more likely to be targeted by organized crime, study shows
Communities with higher-than-average illegal market opportunities (proxied by drug-related activities) are more likely to be targeted by organized crime groups, a new study shows......»»
Genes spatially organize for efficient mRNA splicing, study shows
The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 times smaller than the width of a human hair, genes a.....»»
DeepMind adds a diffusion engine to latest protein-folding software
Major under-the-hood changes let AlphaFold handle protein-DNA complexes and more. Enlarge / Prediction of the structure of a coronavirus Spike protein from a virus that causes the common cold. (credit: Google DeepMind) M.....»»
MATE transporter facilitates bitter saponin transport from cytoplasm to vacuole
Domestic soybeans serve as an important source of healthy edible plant oil and high-quality plant protein in our food culture. In addition to the well-known components of oil (approximately 20%), protein (approximately 40%), and carbohydrates (approx.....»»
Nintendo DMCA Notice Wipes Out 8,535 Yuzu Repos, Mig Switch Also Targeted
After Nintendo filed a full-blown lawsuit against the developers of the Yuzu emulator in February, a rapid settlement effectively ended that phase of the project a little over a week later. In March, Nintendo targeted various related tools, taking do.....»»
How suppliers are tackling four challenging legal and regulatory issues
Suppliers, dealing with a bumpy transition to electric vehicles, new regulations and rocky relationships with some of their customers, are turning to their lawyers to help them navigate issues related to contracts with automakers......»»
New patent for bio-based polymer to be used in piezoelectric devices
UD engineers are the lead inventors on a new patent for making piezoelectric devices, such as sensors and actuators, using Nodax, a biodegradable, bio-based polymer......»»
Engineers develop innovative microbiome analysis software tools
Since the first microbial genome was sequenced in 1995, scientists have reconstructed the genomic makeup of hundreds of thousands of microorganisms and have even devised methods to take a census of bacterial communities on the skin, in the gut, or in.....»»
The strategic advantages of targeted threat intelligence
In this Help Net Security video, Gabi Reish, Chief Business Development and Product Officer at Cybersixgill, discusses the role of threat intelligence in every enterprise’s security stack. Threat intelligence plays a significant role in proacti.....»»
Starliner’s first crewed launch called off just two hours before liftoff
A technical issue has forced NASA engineers to call off Monday's first crewed launch of the Starliner spacecraft just two hours before liftoff......»»
Tesla announces fourth round of layoffs in four weeks
The latest cuts affect engineers, HR, and service advisers. Enlarge (credit: Karol Serewis/SOPA Images/LightRocket via Getty Images) On Sunday night, even more Tesla workers learned they were no longer employed by the c.....»»
Scientists use high pressure NMR spectroscopy to study structure of dynamic proteins
A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest point of the ocean. Th.....»»
Synthetic chemistry approach yields new compounds with potential biomedical applications
Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules found in various living organisms exhibit diverse biological activities, including the ability to modulate protein-protein.....»»
Debates on campus safety in response to Palestine solidarity activism show we need strategies to navigate discomfort
Canada's House of Commons Standing Committee on Justice and Human Rights will soon begin hearings on antisemitism and Islamophobia. The process comes partly in response to claims that university and college campuses are unsafe spaces......»»
Engineers solve "catalysis vs corrosion" mystery in electrochemical ozone production
Researchers at the University of Pittsburgh and Drexel University in Philadelphia, along with Brookhaven National Laboratory, are working to solve a multipart mystery to make water disinfection treatments more sustainable......»»
The benefits of crown-of-thorns starfish control on the Great Barrier Reef
New research has revealed that years of targeted crown-of-thorns starfish control on the Great Barrier Reef has protected coral and supported reef health and resilience......»»
Sister cities can help communities better navigate the climate crisis, research suggests
Anthropologists at Rice University suggest in a new study that establishing networks of 'sister cities' dedicated to addressing the impact of natural disasters can mitigate the devastation wrought by climate change......»»
Making sure ESA"s cloud and aerosol satellite is aerosol-free
A few weeks ago, a team of engineers carefully extracted ESA's EarthCARE satellite from its protective transport container, initiating a meticulous process of inspection, testing and preparation for its liftoff later this month from the Vandenberg la.....»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Stellantis hires engineers in Brazil, India for $53,000 a year to save costs
Stellantis is pursuing an aggressive cost-cutting program and is said to want to have roughly two-thirds of the company’s engineers in lower-cost countries over the longer term......»»