PARP inhibitor shrinks tumors in pancreatic cancer patients with mutations
More than two-thirds of pancreatic cancer patients harboring genetic mutations saw their tumor stop growing or shrink substantially after being switched from intensive chemotherapy to the PARP inhibitor rucaparib as a maintenance therapy......»»
Attacks on health care during war are becoming more common, creating devastating ripple effects
The head of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, has warned attacks on health-care workers, patients and facilities "must not become the norm.".....»»
Researchers discover tumors inherited by generations of jellyfish-like creatures
Researchers from the CANECEV laboratory, an international collaboration between Deakin University and the University of Montpellier, have observed for the first time the birth of transmissible tumors in freshwater brown hydras—tiny, jellyfish-like.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
Exploring the interplay between phosphate signaling and jasmonate pathways in tea plants
Catechins, the key active components in tea, are known for their protective effects against conditions like diabetes, cancer, and cardiovascular diseases. However, their biosynthesis is highly sensitive to environmental factors, particularly phosphat.....»»
First-of-its kind tool allows scientists to manipulate cells without touching them
When studying the spread of cancer or the behavior of a virus like the one that causes COVID-19, the irony is that working with these harmful pathogens requires gentleness. Especially in the case of COVID, the particles do not survive well when makin.....»»
Scientists identify 18 bacterial strains to treat antibiotic-resistant gut infections
Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time. Gram-negative bacteria such as Enteroba.....»»
New Sickle Cell Treatments Reach Patients after Years of Effort
The FDA recently approved three sickle cell drugs, and dozens more are in development.....»»
New Sickle Cell Treatments Highlight the Power of Patient Perspectives
Illuminating the experience of people living with sickle cell could improve patients’ lives and enhance all of medicine.....»»
Sitting in a Chair All Day Can Lead to Disease. Standing Up and Moving Around Every Hour Can Help
Days spent in a desk chair can lead to heart disease or cancer. Getting up often and exercising more vigorously can stave off the ill effects.....»»
Why Early Prostate Cancer Screening Matters for Black Men
According to the American Cancer Society, Black men are about 70 percent more likely than white men to develop prostate cancer in their lifetime and twice as likely to die from the disease......»»
11-year-old felt hip pain and was limping. It was the first sign of stage 4 cancer
11-year-old felt hip pain and was limping. It was the first sign of stage 4 cancer.....»»
Q&A: Authors discuss addressing the crisis of species loss
No oncologist would wait for a patient's cancer to spread before treating it. Similarly, waiting to detect the potential loss of a species across all its known habitats means interventions are often too late to turn the tide of extinction, according.....»»
Scientists decipher the energy patterns in our cells
Our cells harness energy for essential functions such as division, wound healing, and our immune response to diseases including cancer. But until now, the mechanics of how that energy affects cell behavior—and how this relates to health outcomes—.....»»
Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once it escaped a lasso-like "straitjacket.".....»»
Virtual laboratory allows scientists to simulate specific decreases in gene activity
Imagine you're looking at millions upon millions of mysterious genetic mutations. With CRISPR gene-editing technology, a select few of these mutations might have therapeutic potential. However, proving it would mean many thousands of hours of lab wor.....»»
Modified nano-sized cell particles found to boost cancer immunotherapy, reduce side effects
Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively. The treatment involves using substances that bo.....»»
Researchers develop novel covalent organic frameworks for precise cancer treatment delivery
A team of researchers at NYU Abu Dhabi (NYUAD), led by Program Head of Chemistry Ali Trabolsi, have developed nanoscale covalent organic frameworks (nCOFs), crystalline organic polymers that have been modified with peptides to treat the most aggressi.....»»
New technique boosts mutation rates in fruit flies for genetics research
A new technique, TF-High-Evolutionary (TF-HighEvo), allows large-scale assessment of de-novo mutations in multicellular organisms. Developed in collaboration with researchers from the European Molecular Biology Laboratory (EMBL) and the Friedrich Mie.....»»
Iron-doped carbon-based nanoparticles boost cancer treatment with enhanced precision and safety
Recently, a collaborative research team led by Prof. Wang Hui and Prof. Qian Junchao from Hefei Institutes of Physical Science of the Chinese Academy of Sciences designed a catalytically active, photoresponsive, Fe-doped carbon nanoparticle (FDCN) fo.....»»
Experimental nanomedicine delivers chemo drugs directly to tumors in mice
Researchers at the University of Chicago Medicine Comprehensive Cancer Center have developed a nanomedicine that increases the penetration and accumulation of chemotherapy drugs in tumor tissues and effectively kills cancer cells in mice......»»