Oral peptides: A new era in drug development
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require specificity for particular pr.....»»
AI tools help uncover enzyme mechanisms for lasso peptides
Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tes.....»»
Apple calls AirPods design ‘the snorkel,’ plus other AirPods 4 details
AirPods 4 are , and Engadget has a great new interview with the team behind the product. Details include the timing of when development started, how ANC is made possible on an open-ear design, use of the term ‘snorkel,’ and more. more….....»»
AI for drug discovery: DrugSynthMC to make finding new medication more efficient
Scientists have devised a free AI algorithm that they believe will make finding new medicines far more efficient......»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
More than 1,000 homes are being built in Conway as part of a massive development plan
More than 1,000 homes are being built in Conway as part of a massive development plan.....»»
A drug made by a Florida company has been recalled for a possibly lethal contamination
A drug made by a Florida company has been recalled for a possibly lethal contamination.....»»
Was Thalidomide Safe? Frances Oldham Kelsey Was Not Convinced
In the U.S. in the early 1960s the distributor of a thalidomide drug was impatient to get it on the market. But FDA medical examiner Frances Oldham Kelsey wanted more information to prove its safety.....»»
Obesity-Drug Pioneers Win Prestigious Lasker Award for Medical Science
Three scientists are honored for developing a class of blockbuster weight-loss drugs. Is a Nobel prize on the way?.....»»
India approves development of reusable launcher, space station module
The Indian government has approved $2.7 billion in new spending for its space program. Enlarge / Parvesh Sahib Singh Verma and Virendra Sachdeva, two members of Narendra Modi's ruling BJP party, celebrate the landing of India's C.....»»
Homeopathic company refuses to recall life-threatening nasal spray, FDA says
Consumers should stop using SnoreStop, FDA says. Enlarge (credit: Getty | Florian Gaertner) The maker of a homeopathic nasal spray with a history of contamination is refusing to recall its product after the Food and Drug.....»»
Optimism fuels national productivity and innovation
A study of 42 countries over a 20-year span found one factor had a significant impact on investment in research and development. Economic optimism plays a crucial role in boosting national productivity and research and development, according to a new.....»»
New mechanism uncovered for the reduction of emu wings
.Researchers have uncovered a novel mechanism underlying the skeletal reduction and asymmetry of emu wings. Their research reveals that the absence of distal muscle formation results in a lack of mechanostress during development, leading to the obser.....»»
Reducing floodplain development doesn"t need to be complex, say researchers
A paper, titled "How local governments avoid floodplain development through consistent implementation of routine municipal ordinances, plans, and programs," published in Oxford Open Climate Change uncovers evidence suggesting that, contrary to expect.....»»
Okaloosa County official urges calm preparedness ahead of potential tropical development
Okaloosa County official urges calm preparedness ahead of potential tropical development.....»»
Yes, it’s true: The Transformers and G.I. Joe will slug it out in a future movie
A Transformers and G.I. Joe crossover event is in early development at Paramount. Find out what you can expect from the crossover event......»»
In morning raids in Erie, FBI makes arrests on drug, weapon charges. 24 defendants named
In morning raids in Erie, FBI makes arrests on drug, weapon charges. 24 defendants named.....»»
If you build it, will they come? Wildlife corridors need smarter design
As human population and development continue to expand, it's more important than ever to set aside corridors of undeveloped land where wildlife can travel safely, helping to ensure their long-term survival. However, a recent study by the University o.....»»
DNA origami and fluorescent probes can precisely release molecular cargo
In the world of nanotechnology, the development of dynamic systems that respond to molecular signals is becoming increasingly important. The DNA origami technique, whereby DNA is programmed so as to produce functional nanostructures, plays a key role.....»»
Scientists find new epigenetic switch, revealing how genes are regulated in early development
The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early emb.....»»
The Devil in the Details, Chapter One: The Doctor Who Said No to Thalidomide
Starting with her rejection of an FDA application for thalidomide in 1960, physician and pharmacist Frances Oldham Kelsey took a stand against the now infamous drug.....»»