Novel drug prevents amyloid plaques, a hallmark of Alzheimer"s disease
Researchers have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques......»»
Protein prediction technology yields accurate results to efficiently find the best drug candidate for many conditions
Artificial intelligence (AI) has numerous applications in health care, from analyzing medical imaging to optimizing the execution of clinical trials, and even facilitating drug discovery......»»
Proteomic analysis reveals how phosphite contributes to the fight against chemically resistant dieback
Having previously confirmed dieback is resistant to chemical control on crops such as avocados, stone fruits and pines, Curtin University researchers have gained new insights into how phosphite works against the fungus-like disease, in a potential br.....»»
Wegovy Can Keep Weight Off for at Least 4 Years, Research Shows
Users receiving weekly injections saw their weight fall, plateau, and stabilize over the course of a four-year trial—but it’s still unclear how long these effects last after stopping taking the drug......»»
Research identifies mechanism behind drug resistance in malaria parasite
Collaborating researchers have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs—specifically artemisinin (ART)—through a cellular process called transfer ribonucleic acid (tRNA) modification. tRNA m.....»»
Heating proteins to body temperature reveals new drug targets
Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications, new research has found......»»
Study discovers distinct population of "troublemaker" platelet cells appear with aging
As people age, they become more prone to blood clotting diseases, when blood cells called platelets clump together when they don't need to and can cause major issues such as strokes and cardiovascular disease. For decades, scientists have studied why.....»»
Chemical tweaks to a toad hallucinogen turns it into a potential drug
Targets a different serotonin receptor from other popular hallucinogens. Enlarge / The Colorado River toad, also known as the Sonoran Desert Toad. (credit: Mark Newman) It is becoming increasingly accepted that classic p.....»»
Nothing to sneeze at: Experimental model shows pollen can change the weather
More than 80 million Americans suffer from seasonal allergies due to airborne pollen, according to the U.S. Centers for Disease Control and Prevention (CDC). Associated medical costs exceed $3 billion every year, with nearly half of those costs linke.....»»
Areas with more illegal market opportunities more likely to be targeted by organized crime, study shows
Communities with higher-than-average illegal market opportunities (proxied by drug-related activities) are more likely to be targeted by organized crime groups, a new study shows......»»
New DNA origami technique promises advances in medicine
A new technique in building DNA structures at a microscopic level has the potential to advance drug delivery and disease diagnosis, a study suggests......»»
Dogs brought to US must be microchipped, older than 6 months: CDC
Dogs brought into the United States from abroad must be compliant with new rules to help fight rabies in this country, according to updated guidance from the Centers for Disease Control and Prevention issued Wednesday......»»
A multi-stream network for retrosynthesis prediction
Retrosynthesis aims to predict a set of reactants for producing given molecules, which plays a significant part in the biochemistry field, such as molecular pathway design and drug discovery. Most existing methods only benefit from one kind of inform.....»»
Researchers target spermidine production to combat emerging drug resistance in Salmonella
Food-borne diseases like typhoid, caused by Salmonella Typhimurium, are a severe threat to public health, especially in India. The indiscriminate use of antibiotics has allowed this bacterium to become resistant, posing a major hurdle in treating inf.....»»
Study underscores new strategies to fight drug-resistant bacteria
Several billion years ago, a genetic arms race began between bacteria and their viral killers. This seemingly eternal struggle continues today, with implications for diseases killing tens of thousands of people around the world each year......»»
Bsal and beyond: Task force helps stave off amphibian disease threat
Amphibians—like frogs and salamanders—are the most imperiled group of animal species in the world; infectious diseases are among the greatest threats to their existence. After a decade of research, a scientific task force is poised to stave off t.....»»
New research confirms that Beethoven had lead poisoning—but it didn"t kill him
To this day, no one knows for certain what caused the liver and kidney disease that led to Ludwig van Beethoven's untimely death. However, a new letter to the editor in the journal Clinical Chemistry rules out one popular theory, showing that the com.....»»
Study sheds light on cancer cell "tug-of-war"
Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself. The movement of cells into the extracellular matrix (ECM) of neighboring tissue is a.....»»
Nanoparticle researchers develop microfluidic platform for better delivery of gene therapy for lung disease
Drug delivery researchers at Oregon State University have developed a device with the potential to improve gene therapy for patients with inherited lung diseases such as cystic fibrosis......»»
Simulated chemistry: New AI platform designs tomorrow"s cancer drugs
Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen t.....»»
Researchers develop new AI tool for fast and precise tissue analysis to support drug discovery and diagnostics
A team of scientists from A*STAR's Genome Institute of Singapore (GIS) and Bioinformatics Institute (BII) has developed a new AI software tool called "BANKSY" that automatically recognizes the cell types present in a tissue, such as muscle cells, ner.....»»