New technique to make complex molecules for antibiotics and anti-fungal medicines
Scientists invented a pioneering technique to construct molecules discovered in rare sediments from the Bahamas with the potential to help treat disease and infection.....»»
Understanding cellular transcription responses to oxygen deprivation
A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences......»»
New computer algorithm supercharges climate models and could lead to better predictions of future climate change
Earth System Models—complex computer models that describe Earth processes and how they interact—are critical for predicting future climate change. By simulating the response of our land, oceans and atmosphere to manmade greenhouse gas emissions,.....»»
Researchers discover key functions of therapeutically promising jumbo viruses
Antibiotic medicines became a popular treatment for bacterial infections in the early 20th century and emerged as a transformational tool in human health. Through the middle of the century, novel antibiotics were regularly developed in the medication.....»»
Study finds distinct patterns lead to domestic partner homicide
A new study has explored the complex patterns which lead to an intimate partner homicide (IPH), in an effort to better understand and prevent the tragic event happening......»»
New research captures 18 years of US anti-bullying legislation
Between 1999 and 2017, every state has passed a law addressing bullying, and 90% of those states amended or updated their laws, according to research that analyzes the most comprehensive legal data on anti-bullying laws to date......»»
New research reveals terahertz waves" impact on dynamics of nanoconfined water molecules
In a new discovery, researchers have revealed novel insights into the behavior of water molecules confined within nanostructures. Their study, published in Science Advances on April 24, delves into how terahertz (THz) waves influence the dynamics of.....»»
New tool decodes complex, single-cell genomic data
Unlocking biological information from complex single-cell genomic data has just become easier and more precise, thanks to the innovative scLENS tool developed by the Biomedical Mathematics Group within the IBS Center for Mathematical and Computationa.....»»
Plant science research paves the way for deeper understanding of how the plant immune system functions
Researchers in the laboratory of Tessa Burch-Smith, Ph.D. at the Danforth Plant Science Center and the University of Tennessee, Knoxville, are conducting pioneering work to discover how plants transmit information, important molecules, and viruses be.....»»
Microgravity-grown crystals reveal new insights into protein structures
Biochemists have long been working around a blind spot when it comes to proteins. They know that hydrogen constitutes nearly half of the atoms in proteins, but how they contribute to protein function in these complex structures has been less clear. H.....»»
Researchers decipher how an enzyme modifies the genetic material in the cell nucleus
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determin.....»»
Genetic hope in fight against devastating wheat disease
Fungal disease Fusarium head blight (FHB) is on the rise due to increasingly humid conditions induced by climate change during the wheat growing season, but a fundamental discovery by University of Adelaide researchers could help reduce its economic.....»»
A systematic review of three key sugar metabolism proteins: HXK, SnRK1 and TOR
Sugar signaling is one of the most important regulatory signals for plant growth and development, and its metabolic network contains many regulatory factors. Sugar signaling molecules regulate cellular activities and organismal development by interac.....»»
A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»
Philippines" counter-terrorism strategy still stalled after 7 years since the "ISIS siege" on Marawi
Following the 2017 siege of Marawi, the Philippines' counter-terrorism efforts have faced an increasingly complex and unpredictable landscape. While authorities have claimed victory, one which garnered global media attention during the peak of ISIS r.....»»
Synthesis of two new carbides provides perspective on how complex carbon structures could exist on other planets
Researchers at the University of Bayreuth have gained new insights in the field of high-pressure carbon chemistry: They synthesized two new carbides—compounds of carbon and another chemical element—with unique structures. The results may provide.....»»
IRIS beamline at BESSY II gets a new nanospectroscopy end station
The IRIS infrared beamline at the BESSY II storage ring now offers a fourth option for characterizing materials, cells and even molecules on different length scales. The team has extended the IRIS beamline with an end station for nanospectroscopy and.....»»
Freeze casting—a guide to creating hierarchically structured materials
Freeze casting is an elegant, cost-effective manufacturing technique to produce highly porous materials with custom-designed hierarchical architectures, well-defined pore orientation, and multifunctional surface structures. Freeze-cast materials are.....»»
Spotify not adopting new App Store terms in the EU, submits app update with pricing info instead
Apple was hit with a $2 billion fine in the European Union last month for “abusive” App Store rules for music streaming services. In addition to the fine, the European Commission also said Apple must relax its anti-steering rules. As reported.....»»
Scientists map soil RNA to fungal genomes to understand forest ecosystems
If a tree falls in the forest—whether or not anyone registers the sound—one thing is for sure: there are lots of fungi around. Within a forest's soil, hundreds of species decompose debris, mobilize nutrients from that decay, and deliver those nut.....»»
New method could cut waste from drug production
Scientists have developed a sustainable new way of making complex molecules, which could greatly reduce waste produced during drug manufacturing, a study suggests......»»