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A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins

For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»

Category: topSource:  physorgApr 25th, 2024

Rising mercury levels may contribute to declining Steller sea lion populations

A team of researchers from Texas A&M University and other institutions has made a surprising discovery about rising mercury levels in Steller sea lion pups that may have detrimental effects on the endangered species......»»

Category: topSource:  informationweekRelated NewsMay 3rd, 2024

No One Knows How Far Bird Flu Has Spread

With little incentive for US farmers to test their cattle, and many undocumented laborers on dairy farms, the full scale of the outbreak is unclear......»»

Category: gadgetSource:  wiredRelated NewsMay 3rd, 2024

Tweaking isotopes sheds light on promising approach to engineer semiconductors

Research led by scientists at the Department of Energy's Oak Ridge National Laboratory has demonstrated that small changes in the isotopic content of thin semiconductor materials can influence their optical and electronic properties, possibly opening.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Vortex fluidic device can speed artificial liposome production to aid drug functionality

The expansion of clean chemistry applications for the vortex fluidic device (VFD)—invented by Flinders University's Professor Colin Raston—continues with the successful rapid and simplified production of artificial liposomes that could help trans.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Researchers determine large numbers of wild mountain goats are killed every year by avalanches

A multi-institutional team of animal behaviorists, snow impact specialists and biologists from Alaska, Montana, Switzerland and Canada has found that large numbers of wild mountain goats die every year in Alaska due to avalanches. For their study, th.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Novel chemical tool for understanding membrane remodeling in the cell

In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell......»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

New discovery of a mechanism that controls cell division

Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Novel triple drug combination effective against antibiotic-resistant bacteria

Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Physicists create an optical tweezer array of individual polyatomic molecules for the first time

A team of physicists at Harvard University has succeeded in trapping individual polyatomic molecules in optical tweezer arrays for the first time. In their paper published in the journal Nature, the group describes how they achieved their feat and th.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Hadeda ibises" "sixth sense" works best in wet soil: New research is a wake-up call for survival of wading birds

Hadeda ibises (Bostrychia hagedash) are one of the most familiar species of birds across sub-Saharan Africa. They are large, long-legged birds with long, thin beaks for probing invertebrates out of soil, and though they appear dull brown at a glance,.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Lahar detection system upgraded for Mount Rainier

In the shadow of Washington State's Mount Rainier, about 90,000 people live in the path of a potential large lahar—a destructive, fluid and fast-moving debris flow associated with volcanic slopes......»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Rivian taps Volvo executive as COO ahead of new-model launch

Rivian Automotive Inc. hired Javier Varela as its new chief operations officer to help the electric-vehicle maker scale output as it prepares to roll out a lower-cost model geared for the mass market......»»

Category: topSource:  autonewsRelated NewsMay 3rd, 2024

iPhone 16 molds reveal change to MagSafe charging ring

A French website has obtained what appear to be molds of the iPhone 16 line-up, showing what appears to be a small but still notable change to the MagSafe charging ring. The molds also reflect the changes we’re expecting to see to the camera lay.....»»

Category: topSource:  theglobeandmailRelated NewsMay 3rd, 2024

New iPads are close, EU App Store rules, and Apple ID"s new bug on the AppleInsider Podcast

On this week's episode of the AppleInsider Podcast, your regular hosts discuss a change in EU rules for small developers, some Apple ID bugs, iOS 18 leaks — and of course the imminent launch of new iPads.Apple is due to launch new iPads on May 7If.....»»

Category: appleSource:  appleinsiderRelated NewsMay 3rd, 2024

Wildfires in wet African forests have doubled in recent decades, large-scale analysis finds

A new study presents the first large-scale analysis of fire patterns in West and Central Africa's wet, tropical forests. The number of active fires there typically doubled over 18 years, particularly in the Congo Basin. The increases are primarily du.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Team evaluates agricultural management practices in new nitrous oxide accounting method

As greenhouse gases go, nitrous oxide (N2O) is a doozy. With a global warming potential 273 times that of carbon dioxide, mitigating N2O could make a big difference. But before mitigation can happen, it's important to understand where the compound is.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

This 17-inch HP laptop is on sale for just $300 — but hurry!

The HP Laptop 17t, which features a large 17.3-inch HD+ display, is on sale from HP with a $200 discount so you'll only have to pay $300, but you have to hurry......»»

Category: topSource:  digitaltrendsRelated NewsMay 3rd, 2024

Good vibrations: Low-energy lasers induce atomic excitation in semiconductor materials

Semiconductors are a cornerstone of next-generation technology, so a new method to excite atoms in semiconductor materials is likely to excite a broad range of researchers and industries as well......»»

Category: topSource:  physorgRelated NewsMay 2nd, 2024

Pulsed plasma rocket (PPR): Shielded, fast transits for humans to Mars

The future of a space-faring civilization will depend on the ability to move both cargo and humans efficiently and rapidly. Due to the extremely large distances that are involved in space travel, the spacecraft must reach high velocities for reasonab.....»»

Category: topSource:  physorgRelated NewsMay 2nd, 2024

Fluidic telescope (FLUTE): Enabling the next generation of large space observatories

The future of space-based UV/optical/IR astronomy requires ever larger telescopes. The highest priority astrophysics targets, including Earth-like exoplanets, first generation stars, and early galaxies, are all extremely faint, which presents an ongo.....»»

Category: topSource:  physorgRelated NewsMay 2nd, 2024