New modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues a.....»»
New structure gives insight into mRNA export and cancers, and how viruses hijack the process to infect their host
The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the nucleus to the site of protein translation in the cytopl.....»»
Spatial interactomics tool maps protein interactions to fight lung cancer
As Ahmet F. Coskun and his team of researchers continue their mission to create a 3D atlas of the human body, mapping cells and tissues, they're making discoveries that could lead to better treatments for the most common type of lung cancer......»»
Satechi redesigns its hub to fit the new, smaller M4 Mac mini
Satechi has announced its new Mac mini Stand & Hub, a pint-sized hub with a card reader, a NVMe Enclosure — and which brings back USB-A ports.Satechi's new Mac mini M4 Stand & HubApple introduced the new M4 Mac mini in October. The diminutive deskt.....»»
How XProtect protects you from viruses on macOS
XProtect is Apple's Mac virus detection system which keeps your Mac safe. Here's how the protective macOS feature works.XProtect is macOS's malware scaning tool.Viruses and other malware are a constant threat to computers, which web surfers have to w.....»»
Scientists discover a new giant virus that infects freshwater algae
Scientists from the Biology Centre of the Czech Academy of Sciences found forty new freshwater viruses infecting aquatic microorganisms this year. The first one, which they isolated and described in detail, was named Budvirus after the South Bohemian.....»»
Cas9-PE system achieves precise editing and site-specific random mutation in rice
Achieving the aggregation of different mutation types at multiple genomic loci and generating transgene-free plants in the T0 generation is an important goal in crop breeding. Although prime editing (PE), as the latest precise gene editing technology.....»»
Mathematical modeling study demonstrates gene drives could boost malaria control when added to intervention package
The Target Malaria UK modeling team at Imperial College London has published their latest study in Nature Communications, titled "The potential of gene drives in malaria vector species to control malaria in African environments.".....»»
Algorithm predicts DNA methylation in ancient specimens, providing insight into human evolution
Research published in Nature Ecology & Evolution introduces a novel method for inferring DNA methylation patterns in non-skeletal tissues from ancient specimens, providing new insights into human evolution. As DNA methylation is a key marker of gene.....»»
The hidden disease risks of modern housing developments in rural Africa
Tamika Lunn went to Kenya looking for bats. Her task, as a postdoctoral researcher in the lab of U of A biologist Kristian Forbes, was to catch bats to understand if, when and why they carried viruses. A spillover of a bat virus to humans could lead.....»»
CRISPR-based system labels extracellular vesicles with "barcodes" to better understand cell-to-cell communication
Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology......»»
April Fools’ joke results in Japanese firm making a beige ’80s throwback PC case
You can fit lots of modern hardware inside—and prop your monitor on top. Putting out a joke product on April Fools' Day can sometimes be a clever way to quietly gauge the reacti.....»»
When marine algae get sick: How viruses shape microbe interactions
By looking at the tiniest virus-infected microbes in the ocean, researchers are gaining new insights about the marine food web that may help improve future climate change predictions. The new study, co-authored by Wake Forest Assistant Professor of B.....»»
Can AI improve plant-based meats? Using mechanical testing and machine learning to mimic the sensory experience
Cutting back on animal protein in our diets can save on resources and greenhouse gas emissions. But convincing meat-loving consumers to switch up their menu is a challenge. Looking at this problem from a mechanical engineering angle, Stanford enginee.....»»
The First Crispr Treatment Is Making Its Way to Patients
It’s been a year since the gene-editing treatment Casgevy was approved for sickle cell disease and a related blood disorder. It’s finally being infused into patients......»»
Misinformation Really Does Spread like a Virus, Epidemiology Shows
“Going viral” appears to be more than just a catchphrase when it comes to the rampant spread of misinformation.....»»
Which animals carry mpox? Our study identified African forest dwelling rodents as one source
Mpox is a disease caused by the highly infectious monkeypox virus. It's quite easily passed on from one person to another. But it originally came from infected animals......»»
Scientists engineer stable protein complexes for targeted cancer therapies
Researchers from Auburn University, partnering with the University of Basel in Switzerland, have discovered a new way to make a cancer-targeting protein complex more stable, opening doors to better cancer treatments. Led by Dr. Rafael Bernardi from A.....»»
Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
Hands-on with AirPods 4: better in every way
, and they are awesome. As a pair of on-ear wireless earbuds, they are really hard to fault. I have used AirPods 2 for the past five years — skipping the third-generation model due to fit concerns — and AirPods 4 are what I have been waiting for.....»»
A new vertical seed distribution trait for soybean breeding
As the human population increases and protein demand doubles, modern plant breeders must further optimize soybean plant architecture and per plant yield for modern farming systems......»»