Nanoparticle delivery of FZD4 to lung endothelial cells inhibits lung cancer progression and metastases
A recent study from the lab of Tanya Kalin, MD, Ph.D., professor of Child Health and Internal Medicine at the University of Arizona College of Medicine—Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung ca.....»»
Team develops promising new form of antibiotic that makes bacterial cells self-destruct
To address the global threat of antibiotic resistance, scientists are on the hunt for new ways to sneak past a bacterial cell's defense system. Taking what they learned from a previous study on cancer, researchers from the University of Toronto (U of.....»»
Uncovering new regulatory mechanisms in embryo implantation
Implantation is the initial step in pregnancy, where the embryo attaches to and enters the endometrium, the inner tissue layer of the uterus. During this process, the cells of the endometrium change to build the right conditions for the fertilized eg.....»»
Research provides molecular insights into sexual dimorphism of chicken feathers
Birds possess unique skin appendages called feathers that are derived from the outermost layer of skin cells. Feathers are important for several functions, such as flight, temperature regulation, protection from external stimuli, and mating behavior......»»
Molecular "cut and sew" process could accelerate drug design
A innovative molecular "cut and sew" process by University of Dundee scientists has allowed the design of a research tool that will accelerate drug design for diseases for which no other options exist, including cancer......»»
Single-molecule imaging reveals aberrant DNA-binding dynamics of cancer-linked chromatin remodelers
Biophysical chemists from the National University of Singapore (NUS) have uncovered a previously hidden landscape that governs the intracellular organization and dynamics of SWI/SNF chromatin remodelers, an important class of protein complexes that c.....»»
Fast super-resolved microscopy enables structured illumination and extended depth detection
Fluorescence microscopy is a powerful tool in biology, allowing researchers to visualize the intricate world of cells and tissues at a molecular level. While this technique has revolutionized our understanding of biological processes, imaging large a.....»»
A method to switch between optical pulling and pushing forces by altering the shape of Fermi arcs in Weyl systems
Optical forces, which act like an invisible "hand," are capable of precisely controlling tiny particles. Optical tweezers, a well-known tool, use this force to capture and manipulate small objects such as cells, bacteria, and viruses. This effect is.....»»
Biofabrication should be sustainable: Researcher calls for a rethink in current practices
Miriam Filippi, a researcher in the field of soft robotics working on developing bioinspired artificial muscle tissues, believes we can make human activities more ecologically sound by harnessing the power of living cells for bio-hybrid materials......»»
Plant fungus provides new drug target for colorectal cancer therapy
Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide......»»
Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»
Zuckerberg sacks staff on six-figure salaries for abusing office’s food delivery scheme
Zuckerberg sacks staff on six-figure salaries for abusing office’s food delivery scheme.....»»
Apple secretly tapped BYD for long-range EV battery tech, report says
Apple and BYD teamed up around 2017 to build a battery system using lithium iron phosphate cells, Bloomberg reported, signaling just how far the iPhone maker went in its efforts to produce a car......»»
Nanoparticle therapy offers new hope for prostate cancer patients
Prostate cancer is the second leading cause of cancer death among American men. A recent study, conducted by researchers from the University of Virginia, Mount Sinai, the University of Michigan, the University of Texas and others, has demonstrated th.....»»
Electrophysiology study shows how ant toxin causes extreme pain
University of Queensland researchers have uncovered the workings of ant venom by measuring electric currents through individual channels in cells to understand how it causes pain......»»
Microtubule formation mechanism sheds light on how cells build their internal skeleton
Inside every cell, a network of tiny filaments, called the microtubule cytoskeleton, helps maintain the cell's shape, allows it to divide, and transports vital materials from one part of the cell to another. The filaments that form this network, term.....»»
Scientists discover chemical probes for previously "undruggable" cancer target
Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»
Is the physics of red blood cells in bats a key to "artificial hibernation" for humans?
The mechanical properties of red blood cells (erythrocytes) at various temperatures could play an important role in mammals' ability to hibernate. This is the outcome of a study that compared the thermomechanical properties of erythrocytes in two spe.....»»
Highly-stabilized and selective inhibitor for cancer-causing enzyme developed
A team of researchers from the Hebrew University of Jerusalem, the Weizmann Institute of Science, and the University of Tokyo has made a significant breakthrough in the fight against cancer by developing a highly selective inhibitor for an enzyme cal.....»»
New bacteria-based therapy shows promise for fighting cancer
Even as cancer remains a leading cause of death globally, bacteria-based cancer therapy presents an exciting and innovative treatment option. Owing to their ability to penetrate the rigid stromal barrier, bacteria can naturally target solid tumors an.....»»
Calcium transport protein in bacteria offers insights for drug development and food safety
Researchers at Umeå University have revealed details on how bacteria use calcium to regulate vital processes in a way that differs from human cells. This breakthrough is significant in the fight against antibiotic resistance and for increasing safet.....»»