Motor neurons derived from patients point to new possible drug target for ALS
Researchers now report a high-throughput target and drug discovery platform using motor neurons made from ALS patients. Using the platform, they confirmed two known targets and identified an existing class of drugs -- agonists to the dopamine D2 rece.....»»
Attacks on health care during war are becoming more common, creating devastating ripple effects
The head of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, has warned attacks on health-care workers, patients and facilities "must not become the norm.".....»»
New Ryzen 7 9800X3D leak: ‘This legend is unbeatable’
More and more signs point to an imminent release for the AMD Ryzen 7 9800X3D, including the first leaked images of the processor's packaging......»»
SCCMSecrets: Open-source SCCM policies exploitation tool
SCCMSecrets is an open-source tool that exploits SCCM policies, offering more than just NAA credential extraction. SCCM policies are a key target for attackers in Active Directory environments, as they can expose sensitive technical information, incl.....»»
As Expected, Sony’s 30th Anniversary PS5 Pro Falls Prey to Scalpers
It's a bit unsurprising at this point. The post As Expected, Sony’s 30th Anniversary PS5 Pro Falls Prey to Scalpers appeared first on Phandroid. We suppose it was only a matter of time – not too long after Sony announced a spec.....»»
Another building block of life can handle Venus" sulfuric acid
Venus is often described as a hellscape. The surface temperature breaches the melting point of lead, and though its atmosphere is dominated by carbon dioxide, it contains enough sulfuric acid to satisfy the comparison with Hades......»»
NASA confirms space station cracking a “highest” risk and consequence problem
NASA and Roscosmos have not agreed on the point at which the leak rate is untenable. Enlarge / A high-resolution commercial Earth-imaging satellite owned by Maxar captured this view of the International Space Station on June 7 wi.....»»
Ultrasound technology accelerates drying of renewable cellulose nanocrystals
The global transition towards sustainability has sparked significant interest in bio-based materials and energy-efficient technologies. Among these, cellulose nanocrystals (CNCs), derived from renewable resources, have shown great potential for use i.....»»
Toyota deflects attack by anti-DEI activist over LGBTQ programs
Toyota Motor Corp. distanced itself from some of its LGBTQ initiatives and said it doesn’t have a quota system to boost diversity among its suppliers.....»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
Improving industrial scale lactoferrin production with synthetic biological systems
Lactoferrin (LF), a multifunctional glycoprotein of the transferrin family, is naturally expressed in human and cow milk. The name "LF" is derived from its ability to bind to iron (ferrin, a suffix indicating iron-binding protein)......»»
Biofuel production: Rhodococcus strain N1-S transforms succinic acid production
As the global push for sustainable biofuels intensifies, lignocellulosic biomass has emerged as a prime candidate for biofuels and biochemicals owing to its abundance and renewability. This biomass, derived from plant materials, holds great promise a.....»»
Advancing synthetic Ephedra-type alkaloids with a two-step enzymatic approach
Ephedra-type alkaloids, a class of naturally occurring compounds derived from plants in the genus Ephedra, have long held interest in the pharmaceutical industry due to their stimulant and airway widening effects. These alkaloids are used for the tre.....»»
Violence, harassment from students is overwhelmingly "part of the job" for Saskatchewan education sector workers
Saskatchewan education sector workers are experiencing disturbing levels of workplace violence and harassment, says a new report spotlighting a situation that has reached "a breaking point," according to its authors......»»
Neutron experiments settle 40-year debate on enzyme for drug design
In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers......»»
Former Mitsubishi dealer must pay Nissan lending arm $330K debt, Nebraska judge rules
A bankruptcy court judge in Nebraska has refused to dismiss a $331,225 debt a former Mitsubishi dealer and his company owe to floorplan lender Nissan Motor Acceptance Co......»»
Gun violence in Philadelphia plummeted in 2024—researchers aren"t sure why, but here are 3 factors at play
Philadelphia experienced a surge in shootings and homicides during the COVID-19 years that disproportionately affected young Black and Latino men in economically disadvantaged neighborhoods with drug markets......»»
Can our stockpiles of Tamiflu protect against a bird flu pandemic?
Governments are banking on this old drug in the event of an H5N1 outbreak. Enlarge / A box and a tablet of Roche Pharmaceuticals' Tamiflu pills for influenza. (credit: Nikos Pekiaridis/NurPhoto via Getty Images) Since re.....»»
Proof-of-concept study uses X-rays to target mock-up asteroids in a vacuum
An X-ray pulse may be able to vaporize the surface of an asteroid and change its trajectory, according to a proof-of-concept paper published in Nature Physics. A laboratory experiment that mimics the deflection of an asteroid model using this techniq.....»»
Elon Musk shares new target date for Starship voyage to Mars
But it's worth noting that the SpaceX CEO's forecasts often slip......»»
Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?
Viking Therapeutics, Inc. (VKTX): Biotech Breakthrough or Short Sellers’ Target?.....»»