Moonlighting protein makes a hospital germ harmful
The Pseudomonas aeruginosa bacterium is a widespread and dangerous hospital germ. It infects the respiratory tract and lungs and possesses natural resistance to numerous antibiotics. There is an ongoing search for so-called pathoblockers to be able t.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Researchers identify effective materials for protecting astronauts from harmful cosmic radiation on Mars
Researchers have identified specific materials, including certain plastics, rubber, and synthetic fibers, as well as Martian soil (regolith), which would effectively protect astronauts by blocking harmful space radiation on Mars. These findings could.....»»
Research unravels dual role of membrane protein in rice ethylene signal transduction
A research team, led by Professor Zhang Jinsong from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences, revealed insights into the mechanism by which the membrane protein MHZ3 collaborates with the ethylene.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
Cryo-ET study elucidates protein folding helpers in their natural environment
Cryo-electron tomography (cryo-ET), can be used to visualize and analyze cellular structures in their natural environment. Researchers at the MPI of Biochemistry in Martinsried and the University Medical Center Göttingen have now used cryo-ET to stu.....»»
Self-repairing mitochondria use novel recycling system, study finds
Mitochondria depend on a newly discovered recycling mechanism identified by scientists at The Hospital for Sick Children (SickKids)......»»
Calls to ban "harmful pornography" are rife—here"s what teens actually think about porn
Pornography has been in the news a lot this year. It was at the center of discussions addressing violence against women back in May. Deepfake pornography has also been in the headlines......»»
Study discovers an electric current in the gut that attracts pathogens like Salmonella
How do bad bacteria find entry points in the body to cause infection? This question is fundamental for infectious disease experts and people who study bacteria. Harmful pathogens, like Salmonella, find their way through a complex gut system where the.....»»
Comparing methods for extracting edible protein from mealworms
Edible insects are emerging as an alternative protein source that has various benefits compared with conventional animal sources. New research published in the Journal of Food Science compared four different methods for extracting protein from mealwo.....»»
CEO of failing hospital chain got $250M amid patient deaths, layoffs, bankruptcy
Steward Health Care System, run by CEO Ralph de la Torre, filed for bankruptcy in May. Enlarge / Hospital staff and community members held a protest in front of Carney Hospital in Boston on August 5 as Steward has announced it.....»»
Researchers teach artificial intelligence about frustration in protein folding
Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict.....»»
Researchers develop nanoparticle array implantation for sensitive and reusable detection
Shanghai Jiao Tong University (SJTU) researchers have developed a highly sensitive and reusable surface-enhanced Raman spectroscopy (SERS) microfluidics system that has achieved a detection limit lower than 10 ppt (parts per trillion) of harmful subs.....»»
Exploring Huntington"s disease: Researchers discover that protein aggregates poke holes in the nuclear membrane
Researchers at Utrecht University in the Netherlands have identified a new way in which the toxic protein aggregates associated with Huntington's disease may damage nerve cells and cause them to die......»»
Newly discovered protein stops DNA damage
Researchers from Western University have discovered a protein that has the never-before-seen ability to stop DNA damage in its tracks. The finding could provide the foundation for developing everything from vaccines against cancer, to crops that can.....»»
Enhanced model enables more realistic biofilms for studying ventilator pneumonia
Scientists at The University of Warwick have made a breakthrough which could help find new treatments for a deadly infection that can affect up to 40% of hospital patients using mechanical ventilators. The study is published in Microbiology......»»
Wildfires are increasing toxic mercury in streams in Idaho, Oregon, Washington, study finds
Wildfires have been burning across Idaho this summer, and their list of harmful impacts is long, from worsening health conditions because of smoke to challenges recovering millions in costs to fight them......»»
Surprise finding in study of environmental bacteria could advance search for better antibiotics
In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial.....»»
Two Point Museum is a worthy follow-up to Two Point Hospital and Campus
Two Point Museum takes the charming management gameplay of Two Point Hospital and Two Point Campus and applies it to running a museum......»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»