Monopolies Are Getting in the Way of mRNA Vaccines
Developing nations that desperately need these more effective vaccines are virtually locked out -- Read more on ScientificAmerican.com.....»»
Study: Nanoparticle vaccines enhance cross-protection against influenza viruses
To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection, according to a study by researchers in the Insti.....»»
Vaccines Are the Safest Health Hack
Vaccines are a cornerstone of a healthy immune system—and a healthy life.....»»
Team pioneers a "one-pot platform" to promptly produce mRNA delivery particles
Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network. The programmer, armed with the lifesaving code, must navigate.....»»
US Government Awards Moderna $176 Million for mRNA Bird Flu Vaccine
As fears of a pandemic mount, the biotech company’s mRNA vaccine trial is set to release Phase 1/2 results later this year, with a larger Phase 3 trial expected to begin in 2025......»»
New mRNA technology turns cells into long-lasting drug factories
A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body,.....»»
US prepares for bird flu pandemic with $176M Moderna vaccine deal
Phase 3 trial is expected to begin next year. Enlarge (credit: Getty | Justin Sullivan) The US government will pay Moderna $176 million to develop an mRNA vaccine against a pandemic influenza—an award given as the high.....»»
Scientists are testing mRNA vaccines to protect cows and people against bird flu
The bird flu outbreak in U.S. dairy cows is prompting development of new, next-generation mRNA vaccines—akin to COVID-19 shots—that are being tested in both animals and people......»»
As bird flu spreads in cows, US close to funding Moderna’s mRNA H5 vaccine
If trials are successful, US government likely to buy doses for vaccine stockpile. Enlarge (credit: Digicom Photo/Science Photo Library via Getty) The US government is nearing an agreement to bankroll a late-stage trial.....»»
Do We Have Enough Bird Flu Vaccines for a Potential Pandemic?
The U.S. government has a stockpile of H5N1 vaccines, and several companies could make millions more if needed. But scaling up the supply could take time.....»»
Nanoparticle vaccines: A potential leap forward in veterinary medicine
Classical vaccines often rely on traditional technologies, such as live attenuated or inactivated pathogens, which carry inherent risks including reduced immunogenicity under certain conditions and potential safety concerns. This has spurred the need.....»»
Scientists" new drug-delivery technology is possible breakthrough for multi-strain vaccines
A new way to deliver drugs using a common protein could be used to develop mosaic vaccines, which are vaccines effective against multiple strains of a virus like COVID-19, among other medicines in a global first......»»
Lipid nanoparticle-mRNA regimen reverses inflammation and aids recovery from diabetic wounds in mice
Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown t.....»»
Finding the chink in coronavirus"s armor—experiment reveals how the main protease of SARS-CoV-2 protects itself
The COVID-19 pandemic resulted in millions of deaths. Despite an unparalleled collaborative research effort that led to effective vaccines and therapies being produced in record-breaking time, a complete understanding of the structure and lifecycle o.....»»
Genes spatially organize for efficient mRNA splicing, study shows
The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 times smaller than the width of a human hair, genes a.....»»
An adjuvant made in yeast could lower vaccine cost and boost availability
Vaccines save lives, as proven during the recent pandemic, but one component of most vaccines—including the Novavax COVID-19 vaccine—goes unheralded: a molecule or other compound that primes the immune system to mount a more robust defense agains.....»»
Doc who claimed COVID shots cause magnetism gets medical license back
She also claimed cities liquified dead bodies and poured them into the water supply. Enlarge / Cleveland doctor Sherri Tenpenny gives false testimony on June 8, 2021, saying COVID-19 vaccines magnetize people. (credit: The Ohio.....»»
Decoding development: mRNA"s role in embryo formation
A new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study sheds light on the intricate process of mRNA regulation during embryonic development, providing novel insights into how pluripotent cells a.....»»
Developing a tech platform for fast, robust series production of nanoparticles
Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are neede.....»»
Engineers muffle invading pathogens with a "molecular mask"
Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop. Rapidly mutating viruses such as SARS-CoV-2 can blunt their effectiveness and even render them obsolete......»»
A new coating method in mRNA engineering points the way to advanced therapies
Medicine can help to treat certain illnesses; for example, antibiotics can help overcome infections, but a new, promising field of medicine involves providing our body with the "blueprint" for how to defeat illnesses on its own......»»