Molecular mechanism of ZDHHC18-mediated palmitoylation of cGAS in innate immunity inhibition
Cyclic GMP-AMP synthase (cGAS), a double-stranded DNA (dsDNA) sensing protein, plays an important role in the strong innate immune response induced by pathogen derived nucleic acids......»»
"Bouncing" comets could deliver building blocks for life to exoplanets
How did the molecular building blocks for life end up on Earth? One long-standing theory is that they could have been delivered by comets. Now, researchers from the University of Cambridge have shown how comets could deposit similar building blocks t.....»»
Preventing pollen-mediated gene flow from transgenic camelina using engineered cleistogamy
Camelina sativa (L.) Crantz. is native to Europe and Central Asia, and cultivated as an oilseed crop in Europe, Asia, and North America. It is not only rich in nutrients, such as a high content of unsaturated fatty acids, but it also possesses valuab.....»»
ALMA observations shed more light on molecular clouds associated with supernova remnant LHA 120-N49
Using the Atacama Large Millimeter/Submillimeter Array (ALMA), an international team of astronomers has observed a supernova remnant known as LHA 120-N49. Results of the observational campaign, published November 3 on the pre-print server arXiv, prov.....»»
How green algae count cell divisions illuminates key step needed for the evolution of multicellular life
An international research team led by James Umen, Ph.D., member, Donald Danforth Plant Science Center has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division. Chlamyd.....»»
Researchers reveal evolutionary secret underlying the rise of seed plants
In a study published in Nature Plants, Chao Daiyin's group at the Center for Excellence in Molecular Plant Sciences of the Chinese Academy of Sciences and Lyu Shiyou's group at Hubei University have revealed, for the first time, the mystery behind th.....»»
The unsafe Safeguard Mechanism: How carbon credits could blow up Australia"s main climate policy
A time bomb is ticking inside the Albanese government's climate policy. When it explodes, Australia will fall short of its climate targets and leave a gaggle of investors shirtless......»»
New work sheds light on inner working of cells
CÚRAM researchers at University of Galway, together with colleagues at the Centre for Molecular Nanometrology at University of Strathclyde have published work unveiling the inner workings of cells......»»
Molecular secrets behind "zigzag" hair patterns uncovered, offering an avenue for anti-aging solutions
RIKEN researchers have discovered how biological rhythms influence hair growth in mice. This finding could pave the way for novel anti-aging treatments in humans......»»
Pioneering automated proteoform imaging
Investigators led by Neil Kelleher, Ph.D., professor of Medicine in the Division of Hematology and Oncology and of Biochemistry and Molecular Genetics, have developed an automated technique for imaging and identifying proteoforms in ovarian cancer ti.....»»
Team creates synthetic enzymes to unravel molecular mysteries
A University of Texas at Dallas bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone, and blood in vertebrate embryos......»»
Crumpled sheets reveal a mechanism for glassy relaxations
We often crumple a scrap piece of paper into a ball before throwing it. This mundane action, however, creates a unique complex system with surprising mechanical properties. Take a thin plastic sheet such as cellophane and try it yourself. While a reg.....»»
Research explores molecular basis of ventilator-induced diaphragm weakness
A study, published in PNAS Nexus, presents evidence that mitochondrial fragmentation is a proximal mechanism underlying ventilator-induced diaphragm dysfunction (VIDD)—and identifies a possible therapeutic to limit diaphragm atrophy during a stay.....»»
Identifying a silicon transporter to improve the yield of rice
Silicon (Si) is abundant in terrestrial environments and accounts for 0.1% to 10% of a plant's dry weight. Certain plant species show high levels of Si accumulation, and research has identified high Si accumulation as a protective mechanism against a.....»»
Microsoft Authenticator suppresses suspicious MFA notifications
Microsoft has quietly rolled out a new mechanism that shields users of its mobile Authenticator app from suspicious (and annoying) push notifications triggered by attackers. Preventing attacks relying on MFA fatigue When faced with MFA-protected acco.....»»
An optical and electrically driven single-molecule Raman switch
The role of molecular junctions in nanoelectronics is most often associated with electronic transport; however, their precise characterization hinders their widespread development. Recently, most research has focused on investigating molecular juncti.....»»
Research shows that photorespiration does not protect against fluctuating light conditions
Photosynthesis is one of the most important metabolic processes in nature: It is critical for plant growth and thus for the production of plant-based foods. In close cooperation with the Max Planck Institute of Molecular Plant Physiology (MPI-MP), a.....»»
The cell"s "read–write" mechanism: Researchers uncover how instructions for gene expression are relayed
The "read–write" mechanism by which cells replicate and use chemical instructions for expressing genes has been uncovered by RIKEN researchers. The quality and quantity of gene expression correlates not only with instructions by transcription facto.....»»
Scientists reveal new mechanism for dynamic regulation of manchette microtubules during sperm development
Researchers led by Meng Wenxiang from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have shown that knocking out of the calmodulin-regulated spectrin-associated protein 1 (CAMSAP 1) gene, which is associated w.....»»
Researchers reveal hidden sensory mechanism of hair follicles
Imperial researchers have discovered a hidden mechanism within hair follicles that allow us to feel touch. The findings have been published in Science Advances......»»
Making high-quality crystals that resonate strongly with infrared light
Combining electronics with infrared light can enable small, fast, and sensitive devices for sensing, imaging, and signaling at the molecular level. However, in the infrared spectrum, materials must meet strict quality requirements for their crystals.....»»