Molecular mechanism of ZDHHC18-mediated palmitoylation of cGAS in innate immunity inhibition
Cyclic GMP-AMP synthase (cGAS), a double-stranded DNA (dsDNA) sensing protein, plays an important role in the strong innate immune response induced by pathogen derived nucleic acids......»»
Researchers uncover new infection-fighting molecules through "molecular de-extinction"
A new study led by Cesar de la Fuente, Ph.D., Presidential Assistant Professor of Psychiatry, Microbiology, Chemistry, Chemical and Biomolecular Engineering, and Bioengineering at the University of Pennsylvania, has uncovered sequences for infection-.....»»
Diagnostic test that combines two technologies with machine learning could lead to new paradigm for at-home testing
A new diagnostic test system jointly developed at the University of Chicago Pritzker School of Molecular Engineering (PME) and UCLA Samueli School of Engineering fuses a powerful, sensitive transistor with a cheap, paper-based diagnostic test. When c.....»»
A roadmap for using viruses to enhance crop performance
Humans, livestock and companion animals benefit from virus-based vaccines and gene therapies, but crops do not. This paradox is highlighted by an international research group led by the Institute of Molecular and Cellular Biology of Plants (IBMCP) wi.....»»
Steering molecular twisting for hydrogen generation
Researchers from the Faculty of S&T at the University of Twente have developed a novel approach for the design of efficient solar fuel devices. Research performed by graduated Ph.D. student Kaijian Zhu shows that reducing the light-induced twisting o.....»»
Researchers reveal performance boost mechanism in single-atom catalyst for oxygen evolution reaction
Hydrogen energy, with its green, low-carbon and high-calorific-value properties, is emerging as the new key to solving the energy crisis. Electrochemically, water splitting has garnered much attention as a promising hydrogen production technique. How.....»»
Researchers examine protein arrangement in cell membrane that triggers programmed cell death
How can molecular structures be analyzed when the resolution of the techniques available is not sufficient? Researchers from the fields of physics, chemistry and medicine at Heinrich Heine University Düsseldorf (HHU) have combined and further develo.....»»
Scientists learn how to drug wily class of disease-causing enzymes
UCSF scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be "undruggable.".....»»
Nanoscale silver exhibits intrinsic self-healing abilities without external intervention
As an innovative concept in materials science and engineering, the inspiration for self-healing materials comes from living organisms that have the innate ability to self-heal. Along this line, the search for self-healing materials has been generally.....»»
Researchers develop molecular biosensors that only light up upon binding to their targets
Biosensors—devices that use biological molecules to detect the presence of a target substance—have enormous potential for detecting disease biomarkers, molecules-in-action in diverse biological processes, or toxins and other harmful substances in.....»»
Labs collaborate to enhance imaging tools for cell observation
Two labs at the University of Utah's Department of Chemistry joined forces to improve imaging tools that may soon enable scientists to better observe signaling in functioning cells and other molecular-scale processes central to life......»»
Drosophila study discovers mechanism that could control longevity, cancer cell production
Researchers at UC Merced have used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging......»»
Unveiling the molecular mechanisms linking aging with neurodegenerative diseases
Aging is the prime cause of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. But what exactly increases the prevalence of these brain disorders as one grows older? The molecular forces l.....»»
Cold-atom simulator demonstrates quantum entanglement between electronic and motional states
Researchers from the Institute for Molecular Science have revealed quantum entanglement between electronic and motional states in their ultrafast quantum simulator, generated by the repulsive force due to the strong interaction between Rydberg atoms......»»
Cells use alternative splicing to regulate gene expression, research suggests
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of proteins that can be generat.....»»
Study finds RNA molecule controls butterfly wing coloration
A team of international researchers has uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings. In a study published in the Proceedings of the National Academy of Sciences, the team, led by Luca L.....»»
Study combines data and molecular simulations to accelerate drug discovery
Researchers from the University of Cincinnati College of Medicine and Cincinnati Children's Hospital have found a new method to increase both speed and success rates in drug discovery......»»
Researchers explore design of polar crystalline solids of pure molecular materials
Harmeet Bhoday, a Missouri S&T Ph.D. student in chemistry from Chandigarh, India, was the lead author of an article titled "Perfect Polar Alignment of Parallel Beloamphiphile Layers: Improved Structural Design Bias Realized in Ferroelectric Crystals.....»»
Novel encoding mechanism unveiled for particle physics
In the development of particle physics, researchers have introduced an innovative particle encoding mechanism that promises to improve how information in particle physics is digitally registered and analyzed. This new method, focusing on the quantum.....»»
Chiral molecule research achieves near-complete separation in quantum states
In a study titled "Near-complete chiral selection in rotational quantum states" published in Nature Communications, the Controlled Molecules Group from the Molecular Physics Department of the Fritz Haber Institute has made a significant leap forward.....»»
Big-name publishers are refusing to let Apple Intelligence train on data
Website owners have a simple mechanism to tell Apple Intelligence not to scrape the site for training purposes, and reportedly major platforms like Facebook and the New York Times are using it.Future expansions to Apple Intelligence may involve more.....»»