Modifications to amino acids in sperm could be behind infertility
Sperm play a critical role in the creation of new life, delivering essentially half of the genetic material required......»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
Researchers discover high levels of non-coding RNAs in testes, suggesting new roles in sperm function and evolution
Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had been previously esti.....»»
Researchers create ADP- or ATP-containing molecules with improved yield and consistency
Adenosine diphosphate (ADP) or adenosine triphosphate (ATP)-containing important biological molecules can modify macromolecules like proteins and nucleic acids to alter their function in the cell. Synthesizing ADP- and ATP-containing molecules using.....»»
New nanoparticle delivery method targets sickle cell mutations in bone marrow
Current gene therapies to treat sickle cell disease are complex, time-consuming, and are sometimes linked to serious side effects like infertility or blood cancer. To address these challenges, Johns Hopkins researchers have developed special nanopart.....»»
Signatures of life could survive near surfaces of the moons Enceladus and Europa, NASA experiment suggests
Europa, a moon of Jupiter, and Enceladus, a moon of Saturn, have evidence of oceans beneath their ice crusts. A NASA experiment suggests that if these oceans support life, signatures of that life in the form of organic molecules (e.g. amino acids, nu.....»»
Discovery of a tRNA modification enzyme that also acts on nucleosides
The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»
Asexual reproduction usually leads to a lack of genetic diversity. Not for these ants
Genetic diversity is essential to the survival of a species. It's easy enough to maintain if a species reproduces sexually; an egg and a sperm combine genetic material from two creatures into one, forming a genomically robust offspring with two disti.....»»
Team investigates chemical modifications to gain deeper insights into genetic regulation mechanisms
University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation, according to the paper, "Drosophila.....»»
Tiny TnpB: The next-generation genome editing tool for plants unveiled
Genome editing stands as one of the most transformative scientific breakthroughs of our time. It allows us to dive into the very code of life and make precise modifications. Imagine being able to rewrite the genetic instructions that determine almost.....»»
How to mitigate fraud on iOS devices using App Attest and DeviceCheck
App developers can minimize fraud by using App Attest and DeviceCheck, two tools provided by Apple. Here's how to use them to prevent unauthorized modifications to your app, and to prevent users from illegitimately acquiring premium content.App Attes.....»»
Photoenzymatic synthesis achieves efficient oxidation of fatty acids
A research team designed and built a photoenzymatic cascade by combining photochemical water oxidation/O2 reduction with P450 peroxygenase catalysis to achieve efficient visible-light-driven oxidation of a range of fatty acids (C12-C20), leading to p.....»»
AI approach optimizes development of antibody drugs
Proteins have evolved to excel at everything from contracting muscles to digesting food to recognizing viruses. To engineer better proteins, including antibodies, scientists often iteratively mutate the amino acids—the units that are arranged in a.....»»
Researchers uncover protein SRSF1"s uncommon ability to bind and unfold RNA G-quadruplexes
RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department of Chemistry Professor Jun Zhang, Ph.D., and his te.....»»
New method uses light to enable the generation of non-canonical amino acids
UC Santa Barbara researchers are building out the repertoire of chemical reactions, using light. In a paper published in the journal Nature, chemistry professor Yang Yang and collaborators at the University of Pittsburgh report a method using photobi.....»»
Researchers find high concentrations of D-amino acids and D-lactate in estuarine polychaetes
A research group has discovered that high concentrations of D-amino acids, in addition to L-amino acids, are present in the body tissues of polychaetes and that their composition is species-specific......»»
Understanding how zwitterionic polymers can lead to safer drugs and disease prevention
Proteins are vital biomolecules responsible for performing various functions in the human body and are thus regarded as the workhorses of a cell. The primary structure of a protein is composed of different amino acids coming together. The structure s.....»»
New findings on fertility: Sperm can adapt to sexually transmitted microbes
Researchers from Dresden University of Technology (TUD) and the University of Sheffield have discovered that male fertility can adapt to microbes. These findings shed new light on the importance of sperm ecology and might have significant implication.....»»
Shedding light on the chemical enigma of sulfur trioxide in the atmosphere
Researchers at Tampere University have discovered that sulfur trioxide can form products other than sulfuric acid in the atmosphere by interacting with organic and inorganic acids......»»
China"s low-cost EV is coming to upend Europe"s vaunted turf
Even after tariffs and modifications to meet European standards, BYD executives have pledged to sell the Seagull for less than €20,000. .....»»
By listening, scientists learn how a protein folds
By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein......»»