Methylated cyclodextrin effectively prevents the crystallization of supersaturated drugs
In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency. Solubilizing agents such as cyclodextrins (CDs) are c.....»»
New nanoparticle prevents mineral buildup in equipment handling water-oil mixtures
In the process of oil extraction, hard mineral buildup inside the pipes and equipment can cause serious operational damage, safety issues such as pipe explosion and significant economic losses. The current methods for descaling mineral buildup, howev.....»»
Better together: Gut microbiome communities found to have enhanced resilience to drugs
Many human medications can directly inhibit the growth and alter the function of the bacteria that constitute our gut microbiome. EMBL Heidelberg researchers have now discovered that this effect is reduced when bacteria form communities......»»
Scientists study how to increase water, nutrient-use efficiency in greenhouses, nurseries
Tom Fernandez, an MSU professor in the Department of Horticulture, has spent much of his 25-year career at MSU studying how to effectively manage water in greenhouses and nurseries to increase water-use efficiency and reduce nutrient runoff......»»
Obesity-Drug Pioneers Win Prestigious Lasker Award for Medical Science
Three scientists are honored for developing a class of blockbuster weight-loss drugs. Is a Nobel prize on the way?.....»»
New Sickle Cell Treatments Reach Patients after Years of Effort
The FDA recently approved three sickle cell drugs, and dozens more are in development.....»»
Do performance rankings effectively motivate salespeople to improve their performance?
Researchers from Vanderbilt University, San Diego State University, University of Denver, and University of Georgia have published a new study that examines how the presentation of performance rankings influences critical outcomes, including salesper.....»»
Researchers develop new method for delivering RNA and drugs into cells
Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA and potent drugs directly into cells, potentially leading to a more effective treatment of diseases......»»
Study finds mine-drainage treatment cost effective, but far more costs lay ahead
New research led by the University of Pittsburgh shows that state and federal appropriations allowing Pennsylvania to treat abandoned mine drainage works to both successfully and cost effectively clean up the acidic water—particularly to the benefi.....»»
Modified nano-sized cell particles found to boost cancer immunotherapy, reduce side effects
Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively. The treatment involves using substances that bo.....»»
Urban forests could help reduce heat-related mortality, study suggests
Across the globe, heat waves are becoming more frequent and more intense. Therefore, how to effectively combat the adverse effects of heat is an increasingly important topic of research......»»
Enzyme-inspired catalyst puts chemicals in right position to make ethers
Taking inspiration from enzymes, chemists at the University of Illinois Urbana-Champaign developed a catalyst to simplify the synthesis of ethers, key functional components of many drugs, foods, personal care items and other consumer goods. The catal.....»»
Experimental nanomedicine delivers chemo drugs directly to tumors in mice
Researchers at the University of Chicago Medicine Comprehensive Cancer Center have developed a nanomedicine that increases the penetration and accumulation of chemotherapy drugs in tumor tissues and effectively kills cancer cells in mice......»»
Solving the side effect problem of siRNA drugs for genetic disease treatment
Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence genes other than the target ones, causing side eff.....»»
Worm study shows risks posed by antidepressants in water
Common drugs such as antidepressants enter the environment via sewage. In her PhD research, Toxicologist Merel van der Most has shown that this affects the behavior of nematodes. These drugs may also be harmful to many other aquatic creatures. Van de.....»»
Light-activated polymerization methods unlock new possibilities for intracellular applications
Synthetic polymers play a crucial role in cell biology, serving as delivery vehicles for DNA and drugs, acting as fluorescent probes for cellular sensing, functioning as bioinks for tissue engineering, and mimicking biological functionality (e.g., ar.....»»
New knowledge about cell receptors paves the way for future drugs against intestinal tumors
A new study from Karolinska Institutet published in Nature Communications provides valuable insights into the activation of receptors on the cell surface. The knowledge could lead to new targeted therapies and drugs against intestinal tumors, among o.....»»
Deepfakes: Seeing is no longer believing
The threat of deepfakes lies not in the technology itself, but in people’s natural tendency to trust what they see. As a result, deepfakes don’t need to be highly advanced or convincing to effectively spread misinformation and disinformat.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Don’t waste your money on an OLED gaming monitor
OLED provides the best gaming experience money can buy, but buying in too early can effectively be a waste of money......»»
Researchers identify effective materials for protecting astronauts from harmful cosmic radiation on Mars
Researchers have identified specific materials, including certain plastics, rubber, and synthetic fibers, as well as Martian soil (regolith), which would effectively protect astronauts by blocking harmful space radiation on Mars. These findings could.....»»