Mechanism behind ineffective psoriasis drugs identified
Interleukin-12 -- a messenger molecule of immune cells -- was long considered to trigger the development of psoriasis. Now, researchers have shown that interleukin-12 does not actually cause the skin disease but protects against it. This also explain.....»»
Study reveals superbug MRSA"s double defense against antibiotics
Scientists have discovered the mechanism which allows the superbug methicillin resistant Staphylococcus aureus (MRSA) to become highly resistant to antibiotics, paving the way for new approaches to control infectious disease......»»
New nanocatalyst targets tumors without oxygen
Tumors often contain areas of oxygen-deficient tissue that frequently withstand conventional therapies. This is because the drugs applied in tumors require oxygen to be effective. An international research team has developed a novel mechanism of acti.....»»
Single-molecule tracking technology streamlines drug discovery
New drug discovery is a critical step for improving patients' lives. First, researchers must identify molecules in the body's cells that help drive disease, as these are potential targets for new drugs. The next step is to screen candidate drugs that.....»»
Using machine learning to identify bacterial resistance genes and the drugs to block them
Antibiotic resistance is a growing public health problem around the world. When bacteria like E. coli no longer respond to antibiotics, infections become harder to treat......»»
Tunic found in one of the Royal Tombs at Vergina identified as Alexander the Great"s
An international team of archaeologists, led by Antonis Bartsiokas with Democritus University of Thrace, in Greece, has uncovered evidence that a tunic found in one of the Royal Tombs at Vergina once belonged to Alexander the Great......»»
Antithrombin study proposes new mechanism of action for the plasma protein"s functional role
Antithrombin, a plasma protein, has been reported to control thrombin activity by directly binding to thrombin, as well as to have an anti-inflammatory effect. However, the actual molecular mechanism of the anti-inflammatory effect of antithrombin wa.....»»
Ars Live: What else can GLP-1 drugs do? Join us today for a discussion.
Dr. Daniel Drucker will discuss what's ahead for these blockbuster drugs. News and talk of GLP-1 drugs are everywhere these days—from their smash success in treating Type 2 diab.....»»
Scientists uncover key mechanism in pathogen defense, paving way for new antimicrobial strategies
Researchers have made a significant breakthrough in understanding how certain pathogens defend themselves against the host's immune system......»»
Discovery of critical iron-transport protein in malaria parasites could lead to faster-acting medications
Malaria kills over 600,000 people a year, and as the climate warms, the potential range of the disease is growing. While some drugs can effectively prevent and treat malaria, resistance to those drugs is also on the rise......»»
New class of encrypted peptides exhibits significant antimicrobial properties
In a significant advance against the growing threat of antibiotic-resistant bacteria, researchers have identified a novel class of antimicrobial agents known as encrypted peptides, which may expand the immune system's arsenal of tools to fight infect.....»»
Did Decriminalizing Drugs Such As Fentanyl Cause Opioid Overdose Increase?
Oregon decriminalized hard drugs in 2021 and recriminalized them last month. A new analysis shows the laws likely had little effect on opioid deaths.....»»
The Unsettled Science behind Weight-Loss Drugs for Teens
Wegovy and similar weight-loss medications are becoming widely prescribed for teenagers with obesity, but little is known about their long-term effects.....»»
Unique multidomain enzymes from bacteria identified
Pharmaceutical scientists from the National University of Singapore (NUS) have identified and characterized a unique multidomain enzyme capable of catalyzing two distinct types of reactions, both vital for making drug molecules......»»
Ars Live: What else can GLP-1 drugs do? Join us Tuesday for a discussion.
Dr. Daniel Drucker will discuss what ahead for these blockbuster drugs. News and talk of GLP-1 drugs are everywhere these days—from their smash success in treating Type 2 diabet.....»»
McDonald’s E. coli outbreak grows by 50% in 3 days as lawsuits mount
The CDC believes the risk is now low, but cases could continue to rise. Twenty-six more cases have been identified in a multistate E. coli O157:H7 outbreak linked to McDonald's Qu.....»»
"Well-man" thrown from castle identified from 800-year-old Norse saga
A passage in the Norse "Sverris Saga," the 800-year-old story of King Sverre Sigurdsson, describes a military raid that occurred in AD 1197, during which a body was thrown into a well at Sverresborg Castle, outside Trondheim in central Norway, likely.....»»
Scientists make Wile E. Coyote observation, confirming theory of how solar flares are created
An international collaboration that includes an Oregon State University astrophysicist has identified a phenomenon, likened to the quick-footed movements of an iconic cartoon predator, that proves a 19-year-old theory regarding how solar flares are c.....»»
Natural compound found in flowers blocks activity of an enzyme involved in multiple sclerosis and cancer
Scientists have identified a natural compound that halts the process involved in the progression of certain forms of cancer and demyelinating conditions—those that damage the sheath, known as myelin, that surrounds neurons—such as multiple sclero.....»»
Houston helicopter crash victim identified, family loses life during tour
Houston helicopter crash victim identified, family loses life during tour.....»»
NEW: 84 victims identified in sex trafficking bust that shut down 9 Houston bars
NEW: 84 victims identified in sex trafficking bust that shut down 9 Houston bars.....»»