Hydrogel spheres compose a microporous structure for localized mRNA delivery
In a significant leap forward in the realm of regenerative medicine, a team at the Terasaki Institute for Biomedical Innovation has introduced a pioneering approach to mRNA therapy using microspheres made of gelatin methacryloyl (GelMA)—a gelatin-b.....»»
Ancient protein structure may have enabled early molecular evolution and diversification
In a finding that offers fresh insights into the early evolution of life on Earth, two RIKEN biologists have conducted lab experiments that have revealed a previously unknown protein fold, which is completely absent in modern proteins......»»
Bird Flu Fears Stoke the Race for an mRNA Flu Vaccine
Researchers have been working on mRNA flu vaccines since before the Covid-19 pandemic, but we may get one for bird flu first......»»
Filament structure found to activate and regulate CRISPR-Cas "protein scissors"
CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the most studied proteins today are Cas9 and Cas12, al.....»»
Ring Protect rebrands to Ring Home and adds 24/7 recording
Ring Protect is now Ring Home, and while its pricing structure is the same, it benefits from several cool new features -- including 24/7 recording......»»
Seeing double: Designing drugs that target "twin" cancer proteins
Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites......»»
3D structure of key protein could advance development of hormone-free male contraceptive pill
Melbourne-based scientists behind the development of a hormone-free, reversible male contraceptive pill have, for the first time, solved the molecular structure of the discovery program's primary therapeutic target, significantly increasing the chanc.....»»
Geologists discover mysterious subduction zone beneath Pacific, reshaping understanding of Earth"s interior
University of Maryland scientists uncovered evidence of an ancient seafloor that sank deep into Earth during the age of dinosaurs, challenging existing theories about Earth's interior structure. Located in the East Pacific Rise (a tectonic plate boun.....»»
These 3D-printed pipes inspired by shark intestines outperform Tesla valves
Prototypes control fluid flow in a preferred direction with no need for moving parts. Enlarge / Shark intestines are naturally occurring Tesla valves; scientists have figured out how to mimic their unique structure. (credit: Sara.....»»
OpenAI drops nonprofit status in large-scale reorganization
OpenAI is reportedly planning to scrap the nonprofit structure of its core business in favor of a for-profit model that will be more attractive to investors......»»
How social structure influences the way people share money
People around the globe often depend on informal financial arrangements, borrowing and lending money through social networks. Understanding this sheds light on local economies and helps fight poverty......»»
Record-breaking laser demonstration completes mission
NASA's TBIRD (TeraByte InfraRed Delivery) demonstration and its host spacecraft—the PTD-3 (Pathfinder Technology Demonstrator-3)—have completed their technology demonstration. The TBIRD payload spent the past two years breaking world records for.....»»
Researchers uncover key insights into cholesterol"s structure in cell membranes
A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. Th.....»»
Chemists discover new ways in which single-celled organisms organize their DNA
It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden Ph.D. candidate Samuel Schwab has found that the histones in these organisms are much more diverse.....»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
Deals: M2 iPad Air $530, M4 iPad Pro $385 off, iPhone 16 case discounts from $9, and much more
Happy iPhone 16 delivery day folks! While we have some notable iPad discounts and more, today we are highlighting all of the iPhone 16 accessory deals and price drops we have either secured for 9to5 readers or are tracking for delivery today. There a.....»»
X-Ray Imaging and Spectroscopy Mission unveils black hole and supernova remnant surroundings
The X-Ray Imaging and Spectroscopy Mission (XRISM) has revealed the structure, motion and temperature of the material around a supermassive black hole and in a supernova remnant in unprecedented detail. Astronomers presented the first scientific resu.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
Here’s an exclusive discount on all Nomad iPhone 16 cases for 9to5 readers, plus prev-gen models from $9 (Today only)
It wasn’t easy, but we have managed to secure 9to5 readers an exclusive delivery day deal on the beloved Nomad iPhone 16 cases. The brand is a favorite around here among both staffers and readers, and for good reason, but it’s also not one that g.....»»
NASA"s Chandra finds galaxy cluster that crosses the streams
Astronomers using NASA's Chandra X-ray Observatory have found a galaxy cluster has two streams of superheated gas crossing one another. This result shows that crossing the streams may lead to the creation of new structure......»»
Simulated construction of plant-based fish meat with composite structure via 3D printing
To date, about 90% of fish resources worldwide have already reached their sustainable fishery limit. Meanwhile, intensive farming and aquaculture contribute to significant environmental pollution and degradation. To address both the challenges of lim.....»»