How inflammatory signalling molecules contribute to carcinogenesis
Researchers have managed to identify a previously unknown molecular connection between an inflammatory signalling molecule and one of the main oncogenes......»»
Researchers develop versatile and low-cost technology for targeted long-read RNA sequencing
In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children's Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules......»»
Scientists theorize a hidden phase transition between liquid and a solid
Anything made out of plastic or glass is known as an amorphous material. Unlike many materials that freeze into crystalline solids, the atoms and molecules in amorphous materials never stack together to form crystals when cooled. In fact, although we.....»»
Decoding how molecules "talk" to each other to develop new nanotechnologies
Two molecular languages at the origin of life have been successfully recreated and mathematically validated, thanks to pioneering work by Canadian scientists at Université de Montréal......»»
Gold buckyballs, oft-used nanoparticle "seeds" found to be one and the same
Rice University chemists have discovered that tiny gold "seed" particles, a key ingredient in one of the most common nanoparticle recipes, are one and the same as gold buckyballs, 32-atom spherical molecules that are cousins of the carbon buckyballs.....»»
Air pollution linked with global rise in antibiotic resistance
Antibiotic resistance is a growing threat to global health. In 2019, it caused more than 1.27 million deaths worldwide—and it's projected that antimicrobial resistance (which includes bacterial resistance to antibiotics) may contribute to 10 millio.....»»
A New Idea for How to Assemble Life
How would scientists even recognize biological signs of life beyond Earth? Assembly theory proposes a way to identify molecules made by living systems—even those using unfamiliar chemistries......»»
Bioengineered tool unmasks cancer cells
Cancer cells can evade the body's immune defenses by exploiting a normally helpful and ubiquitous group of molecules known as mucins. Now, Stanford researchers have engineered a biomolecule that removes mucins specifically from cancer cells—a disco.....»»
Research team demonstrates a new "primary standard" for measuring ultralow pressures
A vacuum chamber is never perfectly empty. A small number of atoms or molecules always remain, and measuring the tiny pressures they exert is critical. For instance, semiconductor manufacturers create microchips in vacuum chambers that must be almost.....»»
Bringing ultrafast physics to structural biology reveals the dance of molecular "coherence" in unprecedented clarity
How molecules change when they react to stimuli such as light is fundamental in biology, for example during photosynthesis. Scientists have been working to unravel the workings of these changes in several fields, and by combining two of these, resear.....»»
Using AI to find antibodies is fast and produces unimagined molecules
Automation means drug discovery process is less "artisinal" and more streamlined. Enlarge / Researchers use CyBio FeliX workstations to extract and purify DNA samples for testing (credit: LabGenius) At an old biscuit fac.....»»
Land-use strategies, nutrient conditions contribute to oak decline
New research led by a University of Georgia ecologist sheds light, for the first time, on how land-use disturbance and nutrient conditions play a role in the decline of oak forests. The most promising strategy to address this decline is reduced cutti.....»»
Climate protection: Land use changes cause the carbon sink to decline
Forests can bind large amounts of carbon on the land surface. In this way, they decisively contribute to reducing net greenhouse gas emissions. For some areas, however, data are still lacking. In Eastern Europe, in particular, the network of installe.....»»
AI Is Building Highly Effective Antibodies That Humans Can’t Even Imagine
Robots, computers, and algorithms are hunting for potential new therapies in ways humans can’t—by processing huge volumes of data and building previously unimagined molecules......»»
Researchers use enzymes to develop a new class of materials for biocatalytic processes
Industrial biocatalysis with enzymes is deemed to be a "game changer" in the development of a sustainable chemical industry. Enzymes can be used to synthesize an impressive range of complex molecules, including pharmaceutical substances, under enviro.....»»
A biochip that can be used to perform rapid genetic screening of thousands of molecules
A team of materials scientists and engineers at Stanford University, working with a colleague from ETH Zürich and another from Washington University in St. Louis, has developed a biochip that can be used to screen thousands of molecules and that was.....»»
Social media helped contribute to UPND gains in 2021 Zambia elections, analysis shows
Social media helped contribute to the UPND's impressive victory in the 2021 Zambia elections, new analysis shows......»»
Exploring the self-organizing origins of life
Catalytic molecules can form metabolically active clusters by creating and following concentration gradients—this is the result of a new study by scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS). Their model pred.....»»
New, simple and accessible method creates potency-increasing structure in drugs
Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive—potentially explosive—ingr.....»»
Rio Pará found to contribute high trace metal concentrations to the Amazon estuary
The Amazon River is the largest river in the world. It discharges about one fifth of global freshwater runoff, resulting in a freshwater plume rich in nutrients and trace elements entering the Atlantic Ocean......»»
Bringing back extinct molecules to fight modern bacteria
A team of microbiologists and bioengineers at the University of Pennsylvania has tested the possibility of bringing back extinct molecules to fight modern bacteria. In their study, reported in Cell Host & Microbe, Jacqueline Maasch, Marcelo Torres, M.....»»