How different cancer cells respond to drug-delivering nanoparticles
Using nanoparticles to deliver cancer drugs offers a way to hit tumors with large doses of drugs while avoiding the harmful side effects that often come with chemotherapy. However, so far, only a handful of nanoparticle-based cancer drugs have been F.....»»
Cocaine found in mummified brains reveal that New World drug came to Italy 200 years earlier than thought
Cocaine found in mummified brains reveal that New World drug came to Italy 200 years earlier than thought.....»»
New data science tool greatly speeds up molecular analysis of our environment
A research team led by scientists at the University of California, Riverside, has developed a computational workflow for analyzing large data sets in the field of metabolomics, the study of small molecules found within cells, biofluids, tissues, and.....»»
AI for drug discovery: DrugSynthMC to make finding new medication more efficient
Scientists have devised a free AI algorithm that they believe will make finding new medicines far more efficient......»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
Exploring the interplay between phosphate signaling and jasmonate pathways in tea plants
Catechins, the key active components in tea, are known for their protective effects against conditions like diabetes, cancer, and cardiovascular diseases. However, their biosynthesis is highly sensitive to environmental factors, particularly phosphat.....»»
A drug made by a Florida company has been recalled for a possibly lethal contamination
A drug made by a Florida company has been recalled for a possibly lethal contamination.....»»
Was Thalidomide Safe? Frances Oldham Kelsey Was Not Convinced
In the U.S. in the early 1960s the distributor of a thalidomide drug was impatient to get it on the market. But FDA medical examiner Frances Oldham Kelsey wanted more information to prove its safety.....»»
Obesity-Drug Pioneers Win Prestigious Lasker Award for Medical Science
Three scientists are honored for developing a class of blockbuster weight-loss drugs. Is a Nobel prize on the way?.....»»
Homeopathic company refuses to recall life-threatening nasal spray, FDA says
Consumers should stop using SnoreStop, FDA says. Enlarge (credit: Getty | Florian Gaertner) The maker of a homeopathic nasal spray with a history of contamination is refusing to recall its product after the Food and Drug.....»»
Ford, Kia gain some traction in revamping China operations
Most global automakers, unable to match or catch up with China’s rapid shift to electrified vehicles, and losing market share, still seem to have no idea how to respond other than cutting production......»»
Windows users targeted with fake human verification pages delivering malware
For a while now, security researchers have been warning about fake human verification pages tricking Windows users into inadvertently installing malware. A recently exposed campaign showed how some users end up on these pages. Beware of fake human ve.....»»
First-of-its kind tool allows scientists to manipulate cells without touching them
When studying the spread of cancer or the behavior of a virus like the one that causes COVID-19, the irony is that working with these harmful pathogens requires gentleness. Especially in the case of COVID, the particles do not survive well when makin.....»»
Redwood Materials signs deal to recycle BMW’s EV batteries in the US
The automaker will use recycled materials from Redwood in its American-made EVs. Enlarge / BMW is moving to cylindrical cells for its sixth-generation EV powertrain, which debuts in the Neue Klasse. And now it has a recycling par.....»»
In morning raids in Erie, FBI makes arrests on drug, weapon charges. 24 defendants named
In morning raids in Erie, FBI makes arrests on drug, weapon charges. 24 defendants named.....»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
DNA origami and fluorescent probes can precisely release molecular cargo
In the world of nanotechnology, the development of dynamic systems that respond to molecular signals is becoming increasingly important. The DNA origami technique, whereby DNA is programmed so as to produce functional nanostructures, plays a key role.....»»
The Devil in the Details, Chapter One: The Doctor Who Said No to Thalidomide
Starting with her rejection of an FDA application for thalidomide in 1960, physician and pharmacist Frances Oldham Kelsey took a stand against the now infamous drug.....»»
Sitting in a Chair All Day Can Lead to Disease. Standing Up and Moving Around Every Hour Can Help
Days spent in a desk chair can lead to heart disease or cancer. Getting up often and exercising more vigorously can stave off the ill effects.....»»
Readers Respond to the May 2024 Issue
Letters to the editors for the May 2024 issue of Scientific American.....»»