How chimeric, droplet-forming proteins may contribute to cancer
In the prelude to cancer, genetic mutations can sometimes lead to the formation of chimeric proteins made from parts of two different proteins that are usually separate......»»
An elegant switch regulates production of protein variants during cell division
Our cells contain thousands of proteins that have gone largely undetected and unstudied until recent years: these are variants of known proteins, which cells can make when their protein-building machinery interacts differently with the same stretch o.....»»
Enhancing recombinant protein expression in lettuce
Recombinant proteins are crucial in pharmaceutical and other industries. A production method uses plants as hosts in transient protein expression systems. Researchers at the University of Tsukuba developed a technique to increase recombinant protein.....»»
Researcher finds special proteins are key when antibiotic resistance spreads
Antibiotic resistance is a growing public health problem globally. The problem is exacerbated by the fact that some bacteria that have become resistant to antibiotics have the ability to spread that resistance to other bacteria via secretion systems......»»
Nanoparticle technology demonstrates selective destruction of leukemia cancer cells
A research team, affiliated with UNIST has developed nanoparticles that effectively treat acute myeloid leukemia (AML), offering the potential to reduce side effects while enhancing therapeutic efficacy by selectively targeting and eliminating leukem.....»»
Nitrogen-fixing plant diversity declines with over-fertilization, study finds
Anthropogenic nitrogen deposition and climate change can reduce the competitive advantage of nitrogen-fixing plants, leading to reduced diversity of these plants in a community. Surprisingly, changes in temperature and aridity do not contribute to th.....»»
Study evaluates overall soil arthropod diversity at different geographic scales
Soil arthropods contribute to terrestrial ecosystem functions and services. Previous studies have mainly focused on specific arthropod and non-arthropod taxonomic groups at various geographic scales. However, the patterns of overall soil arthropod co.....»»
Team develops promising new form of antibiotic that makes bacterial cells self-destruct
To address the global threat of antibiotic resistance, scientists are on the hunt for new ways to sneak past a bacterial cell's defense system. Taking what they learned from a previous study on cancer, researchers from the University of Toronto (U of.....»»
Molecular "cut and sew" process could accelerate drug design
A innovative molecular "cut and sew" process by University of Dundee scientists has allowed the design of a research tool that will accelerate drug design for diseases for which no other options exist, including cancer......»»
Single-molecule imaging reveals aberrant DNA-binding dynamics of cancer-linked chromatin remodelers
Biophysical chemists from the National University of Singapore (NUS) have uncovered a previously hidden landscape that governs the intracellular organization and dynamics of SWI/SNF chromatin remodelers, an important class of protein complexes that c.....»»
DNA-binding C2H2 zinc finger proteins also regulate RNA processing, researchers discover
Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, regulating gene expression through various mechanisms. The study significantly expands our understanding of these proteins' funct.....»»
Plant fungus provides new drug target for colorectal cancer therapy
Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide......»»
Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»
Quantum research breakthrough uses synthetic dimensions to efficiently process quantum information
A new study opens the door to cutting-edge solutions that could contribute to the realization of a system capable of processing quantum information in a simple yet powerful way......»»
Volunteering to help strangers seen as greater contribution than caring for friends and family
Americans believe volunteering to help strangers contributes more to society than providing care for family or friends, even though they contribute billions of dollars' worth of labor in unpaid caregiving every year, according to research published i.....»»
Nanoparticle therapy offers new hope for prostate cancer patients
Prostate cancer is the second leading cause of cancer death among American men. A recent study, conducted by researchers from the University of Virginia, Mount Sinai, the University of Michigan, the University of Texas and others, has demonstrated th.....»»
Smart Tech Would Make Your Office Building Greener
Implementing smart technologies like demand-controlled ventilation could reduce the carbon footprint of office buildings, which contribute over one third of fossil fuel emissions globally.....»»
General Motors to contribute $625 million to new JV with Lithium Americas
General Motors will contribute $625 million to a new JV with Lithium Americas, with the money going toward developing the Thacker Pass project in Nevada......»»
General Motors to contribute $625 million ln to new JV with Lithium Americas
General Motors will contribute $625 million to a new JV with Lithium Americas, with the money going toward developing the Thacker Pass project in Nevada......»»
Scientists discover chemical probes for previously "undruggable" cancer target
Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»
Highly-stabilized and selective inhibitor for cancer-causing enzyme developed
A team of researchers from the Hebrew University of Jerusalem, the Weizmann Institute of Science, and the University of Tokyo has made a significant breakthrough in the fight against cancer by developing a highly selective inhibitor for an enzyme cal.....»»