How a key immune protein is regulated in the cell
Scientists at EPFL have determined how a protein that is critical in our first line of immune defense is regulated in the cell to prevent autoinflammatory diseases......»»
Human mouth bacteria reproduce through rare form of cell division, research reveals
One of the most diverse ecosystems on the planet is closer than you think—right inside your mouth. Your mouth is a thriving ecosystem of more than 500 different species of bacteria living in distinct, structured communities called biofilms. Nearly.....»»
Twenty-six states may soon need to regulate cannabis—here"s what they can learn from Colorado and Washington
The U.S. Drug Enforcement Administration has made moves to reclassify marijuana, making it a type of legal but regulated medicine, like Tylenol with codeine or some steroids......»»
3D bioprinting materials offer possibility for better bone and soft tissue repair
3D bioprinting is an advanced tissue engineering technique that builds complex tissues using bioactive substances like living cells and scaffolds. It provides personalized tissue repair solutions, reducing immune rejection by using patient-specific c.....»»
Investigation reveals global fisheries are in far worse shape than we thought—and many have already collapsed
When fish are taken from our oceans faster than they can reproduce, their population numbers decline. This over-fishing upsets marine ecosystems. It's also bad for human populations that rely on fish for protein in their diets......»»
Researchers identify genes for low glycemic index and high protein in rice
A team of researchers at the International Rice Research Institute (IRRI) has identified genes and markers responsible for low glycemic index (GI) and high protein content in rice, using genetics and artificial intelligence classification methods......»»
AI tool maps out cell metabolism with precision
Understanding how cells process nutrients and produce energy—collectively known as metabolism—is essential in biology. Modern biology generates large datasets on various cellular activities, but integrating and analyzing the vast amounts of data.....»»
Light-activated polymerization methods unlock new possibilities for intracellular applications
Synthetic polymers play a crucial role in cell biology, serving as delivery vehicles for DNA and drugs, acting as fluorescent probes for cellular sensing, functioning as bioinks for tissue engineering, and mimicking biological functionality (e.g., ar.....»»
Scientists modify citrus pectin with induced electric field
Pectin, a natural and nontoxic acidic polysaccharide, is widely found in the primary cell wall and inner layer of terrestrial higher plants. The main domains of pectin are homogalacturonan and rhamnogalacturonan I, which contribute to the complexity.....»»
Scientists unlock the secrets of how a key protein converts DNA into RNA
Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Arctic heat waves linked to sea ice loss, new study reveals
Amid global warming, heat waves are striking even the Arctic, a region once considered immune to such extreme weather events. Recent research reveals that these heat waves, particularly in the Barents-Kara Sea (BKS) during the boreal autumn, are not.....»»
Study shows an electrically-activated protein regulates spermatogenesis
Frankenstein's monster was brought to life by the judicious application of a little electricity; and a surprising number of processes in our bodies are regulated by electrical currents too. Now, researchers from Japan reveal that electricity may play.....»»
New knowledge about cell receptors paves the way for future drugs against intestinal tumors
A new study from Karolinska Institutet published in Nature Communications provides valuable insights into the activation of receptors on the cell surface. The knowledge could lead to new targeted therapies and drugs against intestinal tumors, among o.....»»
Using metal ion-linked nanostructures to improve immune response and boost breast tumor treatment
Immune checkpoint blockade (ICB) is one of the primary methods of tumor immunotherapy. However, clinical data have shown that only a portion of patients respond to ICB treatment. Since the tumor's immune-suppressive environment plays a crucial role i.....»»
"Silent" mutations found to have repercussions beyond their own gene
Genetic disorders—like cystic fibrosis and Huntington's disease—are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one nucleotide in a codon is switched. In non-synonymous muta.....»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Light microscopy study reveals molecular density changes during mitotic chromosome condensation
A team of scientists studying cell division developed a special light microscopy system and used it to analyze the molecular density of cellular environments. Their results provide a novel insight into mitotic chromosome condensation in living human.....»»
Discovery explains the chemistry behind the cell"s energy molecule
An international research team led by Professor Magnus Wolf-Watz at Umeå University has discovered how the magnesium atom directs the chemistry that catalyzes the production of the energy molecule ATP in a cell. The study is published in the journal.....»»
New technique paves the way for efficient vitamin D3 production
Scientists have developed a method to produce vitamin D3 (VD3), a vital nutrient for bone health and immune function, with greater efficiency and purity. This breakthrough utilizes intricately designed microchannels carved into glass using ultra-fast.....»»