Henipavirus glycoprotein structure guides therapy, vaccine
Recent molecular findings offer new details on how Nipah and Hendra viruses attack cells, and the immune responses that try to counter this onslaught. The results point toward multi-pronged tactics to prevent and treat these deadly illnesses......»»
Glycans can regulate their own biosynthesis by modifying enzyme activity
Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics. Glycans can be incredibly complex and branched in structure, contributing to the stability of the extracellular domain of cells and.....»»
Largest-Ever Pair of Black Hole Jets Stretches 23 Million Light-Years
Supermassive black holes can expel jets of material so vast and powerful that they may shape the large-scale structure of the cosmos.....»»
The Forgotten Developer of Tamoxifen, a Lifesaving Breast Cancer Therapy
Her name was on the patent for tamoxifen, but Dora Richardson’s story was lost until now.....»»
A Giant Structure in Space Challenges Our Understanding of The Universe
A Giant Structure in Space Challenges Our Understanding of The Universe.....»»
Re-analysis of Milky Way"s central supermassive black hole shows elongated structure
A research team led by Assistant Professor Makoto Miyoshi of the National Astronomical Observatory of Japan (NAOJ) has independently re-analyzed observation data of the supermassive black hole at the center of the Milky Way galaxy obtained and publis.....»»
Synthesis method improves catalytic activity by controlling the surface structure of metal particles
Fine-tuning the reactions that produce hydrogen (H2) for use as a clean fuel is an important endeavor to fight against climate change. Researchers at Tohoku University and the Tokyo University of Science have succeeded in improving the catalytic acti.....»»
Advancing drug delivery: New framework links lipid nanoparticle structure to immune response
A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA medicines beyond vaccines to other therapeutic applications.....»»
On the way to light-controlled medicine: Researchers elucidate the structure of specific photoreceptors
Researchers in biology and medicine have long dreamed of controlling the activities of cells without, for example, having to use chemicals. After all, in a structure as complex as an entire organism, unwanted side-effects can often arise......»»
Newly developed methodology breaks molecular symmetry to back one theory about life"s origin
The vast majority of organic molecules (based on a carbon structure) are not flat, but have a three-dimensional geometry. Various results can be obtained depending on the way the atoms are arranged inside each molecule. In some cases, a molecule and.....»»
Chile launches vaccine that neuters dogs for a year
Chile has launched a vaccine described as the first of its kind that sterilizes dogs for a year and is expected to be sold in several dozen countries......»»
First mRNA vaccine against C. difficile infection developed in animal model
A new vaccine provides hope for treating and even preventing the highly contagious and difficult-to-treat Clostridioides difficile infection, more commonly known as C. difficile or C. diff......»»
Turtle genome provides new clues on the evolution of vertebrates
Scientists from the UAB and Iowa State University have generated the genome assemblies of two hidden-neck turtles. The results, which revealed a new three-dimensional structure of the genome within the phylogenetic group of reptiles, birds and mammal.....»»
Researchers to explore light and ultrasound therapy for melanoma treatment in pigs
Texas A&M University researchers are collaborating on a new project that studies how ultrasound and light can treat melanomas in pigs......»»
Apple strong passwords aren’t entirely random, but are cleverly designed
Whenever an Apple device generates a strong password for you, the structure of those secure passwords isn’t entirely random. Instead, Apple created rules specifically designed to make them easier to type if you ever have to do that manually, and.....»»
Imaging X-ray Polarimetry Explorer helps researchers determine shape of black hole corona
New findings using data from NASA's IXPE (Imaging X-ray Polarimetry Explorer) mission offer unprecedented insight into the shape and nature of a structure important to black holes called a corona. The findings are published in The Astrophysical Journ.....»»
Plant fungus provides new drug target for colorectal cancer therapy
Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide......»»
Cryo-electron microscopy sheds light on endothelin signaling mechanisms
Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used cryo-electron microscopy to examine the complex structure of the endothelin receptor and G protein, which are crucial for signal transdu.....»»
Nanoparticle therapy offers new hope for prostate cancer patients
Prostate cancer is the second leading cause of cancer death among American men. A recent study, conducted by researchers from the University of Virginia, Mount Sinai, the University of Michigan, the University of Texas and others, has demonstrated th.....»»
mRNA vaccines for disease outbreaks can be synthesized in less time with new technique
In an era where viral outbreaks can escalate into global pandemics with alarming speed, the ability to quickly develop new vaccines has become crucial. However, the speed of vaccine production is limited because the mRNA used in it is partly chemical.....»»
Genome sequencing could unlock answers to yellow jacket behavior
The most recognizable yellow jacket at Georgia Tech is made of fabric and foam, but Professor Mike Goodisman and a team of researchers revealed a far more complex cellular structure by successfully sequencing the genome of two local species of yellow.....»»