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Glycerol phosphate serves as a terminator of glycan elongation in cancer malignancy

Dystroglycans on epithelial cell surfaces interact with the extracellular matrix via long sugar chains (called matriglycans), and they are responsible for cell adhesion. Abnormalities in the formation of matriglycans can impair cell adhesion and caus.....»»

Category: topSource:  physorgJun 27th, 2022

Researchers discover new family of bacteria with high pharmaceutical potential

Most antibiotics used in human medicine originate from natural products derived from bacteria and other microbes. Novel microorganisms are therefore a promising source of new active compounds, also for the treatment of diseases such as cancer or vira.....»»

Category: topSource:  informationweekRelated NewsMay 16th, 2024

Self-assembled Na-doped zinc oxide for the detection of lung cancer biomarker VOCs at low concentrations

Developing high-performance gas sensors for the detection of lung cancer markers at low concentrations is a crucial step towards achieving early lung cancer monitoring through breath tests. Metal oxide semiconductors (MOS) have long been sensitive to.....»»

Category: topSource:  theglobeandmailRelated NewsMay 13th, 2024

New method unravels the mystery of slow electrons

Slow electrons are used in cancer therapy as well as in microelectronics. It is very hard to observe how they behave in solids. But scientists at TU Wien have made this possible......»»

Category: topSource:  physorgRelated NewsMay 13th, 2024

Researchers discover new function of oncoproteins

Researchers at the University of Würzburg have discovered a new function of the oncoprotein MYCN: It not only helps cancer cells to grow stronger, but also makes them more resistant to drugs. The study is published in Molecular Cell......»»

Category: topSource:  physorgRelated NewsMay 8th, 2024

Study sheds light on cancer cell "tug-of-war"

Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself. The movement of cells into the extracellular matrix (ECM) of neighboring tissue is a.....»»

Category: topSource:  pcmagRelated NewsMay 7th, 2024

Laboratory and natural strains of intestinal bacterium turn out to have similar mutational profiles

Understanding mutational processes in a cell offers clues to the evolution of a genome. Most actively, mutation processes are studied in human cancer cells, while other genomes are often neglected......»»

Category: topSource:  marketingvoxRelated NewsMay 7th, 2024

Dogma-challenging telomere findings may offer new insights for cancer treatments

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can.....»»

Category: topSource:  physorgRelated NewsMay 7th, 2024

Geologists, biologists unearth the atomic fingerprints of cancer

Scientists at the University of Colorado Boulder and Princeton University have, for the first time, employed a tool often used in geology to detect the atomic fingerprints of cancer......»»

Category: topSource:  physorgRelated NewsMay 6th, 2024

Researchers develop a nanoparticle that can penetrate the blood-brain barrier

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier. Their goal is to kill primary breast cancer tumors and brain metastase.....»»

Category: topSource:  physorgRelated NewsMay 6th, 2024

Simulated chemistry: New AI platform designs tomorrow"s cancer drugs

Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen t.....»»

Category: topSource:  physorgRelated NewsMay 6th, 2024

Nano-drugs hitching a ride on bacteria could help treat pancreatic cancer

Many pancreatic tumors are like malignant fortresses, surrounded by a dense matrix of collagen and other tissue that shields them from immune cells and immunotherapies that have been effective in treating other cancers. Employing bacteria to infiltra.....»»

Category: topSource:  physorgRelated NewsMay 3rd, 2024

Understanding cellular transcription responses to oxygen deprivation

A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences......»»

Category: topSource:  physorgRelated NewsMay 2nd, 2024

Study reveals cancer vulnerabilities in popular dog breeds

Medium-sized dogs have a higher risk of developing cancer than the very largest or smallest breeds, according to a UC Riverside study......»»

Category: topSource:  physorgRelated NewsApr 29th, 2024

Fruit fly helps unlock clues about how organs, tissue and cancer grow

The fruit fly, Drosophila, has been used by scientists for more than 100 years to unravel key features of life on Earth, such as how animals respond to the sun and how the bodies of animals are patterned from head to tail......»»

Category: topSource:  physorgRelated NewsApr 29th, 2024

Scientists study lipids cell by cell, making new cancer research possible

Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors. Scientists are celebrating a new technique that lets them study the fatty contents of cancer cells, one by one......»»

Category: topSource:  theglobeandmailRelated NewsApr 23rd, 2024

A universal framework for spatial biology

Biological processes are framed by the context they take place in. A new tool developed by the Stegle Group from EMBL Heidelberg and the German Cancer Research Center (DKFZ) helps put molecular biology research findings in a better context of cellula.....»»

Category: topSource:  physorgRelated NewsApr 23rd, 2024

TopSpin 2K25 serves up a fun, but safe tennis simulation revival

Publisher 2K has brought a beloved tennis game series back with TopSpin 2K25, but its not a major upgrade from the series' last installment......»»

Category: topSource:  digitaltrendsRelated NewsApr 22nd, 2024

5 movies leaving Prime Video in April 2024 you have to watch

Classics like The Terminator and Emmy winner The Big Short are among five movies leaving Prime Video in April 2024 that you need to watch before they're gone......»»

Category: topSource:  digitaltrendsRelated NewsApr 21st, 2024

"Forgotten city:" the identification of Dura-Europos" neglected sister site in Syria

The Dura-Europos site in modern-day Syria is famous for its exceptional state of preservation. Like Pompeii, this ancient city has yielded many great discoveries, and serves as a window into the world of the ancient Hellenistic, Parthian, and Roman p.....»»

Category: topSource:  physorgRelated NewsApr 20th, 2024

Gregg Orr Auto to pay $325,000 to settle allegations it fired employee with cancer

Gregg Orr Auto Collection agreed to settle a lawsuit in which the U.S. Equal Employment Opportunity Commission alleged an older employee with cancer was fired because of his high medical bills......»»

Category: topSource:  autonewsRelated NewsApr 19th, 2024