Glucagon receptor structures uncover new arrestin interaction mechanism
G protein-coupled receptors (GPCRs) are essential for cell signal transduction and constitute the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple downstream transducers, including G proteins and arresti.....»»
Presence of bacteria in soil makes flowers more attractive to pollinators, study shows
Bacteria that live in soil and help roots fix nitrogen can boost certain plants' capacity to reproduce, according to an article published in the American Journal of Botany describing a study of this mechanism in Chamaecrista latistipula, a legume bel.....»»
Shedding light on a decades-old protein sorting mystery
Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, has proposed and validated a mechanism that addresses a decades-old mystery surrounding epi.....»»
Scientists uncover a critical component that helps killifish regenerate their fins
Spontaneous injuries like the loss of a limb or damage to the spinal cord are impossible for humans to repair. Yet, some animals have an extraordinary capacity to regenerate after injury, a response that requires a precise sequence of cellular events.....»»
Salt Security provides improved API protection with Google Cloud
Salt Security announced its integration with Google Cloud‘s Apigee API Management platform. With this technical collaboration, customers can discover all of their APIs, including shadow and deprecated APIs, apply posture rules, uncover areas of.....»»
Auto companies struggle to recruit and keep software, tech talent
Outdated HR and hiring structures hinder the EV transition as competition for digital talent intensifies, according to Josh Bersin Co......»»
ALICE probes the strong interaction three-body problem with new measurements of hadron–deuteron correlations
In an article recently published in Physical Review X, the ALICE collaboration presented its studies of correlations in the kaon–deuteron and proton–deuteron systems, opening the door to precise studies of the forces in three-body nuclear systems.....»»
Cloud cover and urban structures drastically reduce sunlight in cities
Sunlight plays a crucial role in public health, affecting vitamin D synthesis and psychological well-being. Inadequate exposure to sunlight is associated with various adverse health outcomes, such as cardiovascular diseases, metabolic syndrome, depre.....»»
New rules could help child welfare systems treat parents with disabilities more fairly
Parents with any kind of disability are much more likely to have some type of interaction with the child welfare system than other parents. This means they are more likely than other parents to be reported for child abuse and neglect and more likely.....»»
Ancient DNA helps uncover the Iberian lynx"s potential secret weapon against extinction
Many large mammals have lost genetic diversity, often thanks to the actions of people shrinking their populations. The implications can be severe because without genetic diversity, a population does not have a "genetic database" to fall back on to ad.....»»
Mechanism behind autophagy trigger unveiled
An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy, a self-degradation process cells use to eliminate unneeded or damaged components. In recent years, autophagy has also been.....»»
Discovering new energy levels in atomic hyperfine structures
Since the late 1960s, the Laboratoire Aimé Cotton (LAC) in Orsay, France, has made significant progress in the classification of complex atomic spectra. These advances have been driven both by the development of Fourier transform spectroscopy, and t.....»»
Researchers uncover key insights into cholesterol"s structure in cell membranes
A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. Th.....»»
AI tools help uncover enzyme mechanisms for lasso peptides
Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tes.....»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
Researchers achieve aluminum molecular ring-based rotaxane and polyrotaxane
Rotaxanes have garnered interest for their unique structures consisting of mechanically interlocked axles and macrocycles. Numerous organic macrocycles have been employed to construct rotaxanes, including crown ether, cyclobis(paraquat-p-phenylene),.....»»
New mechanism uncovered for the reduction of emu wings
.Researchers have uncovered a novel mechanism underlying the skeletal reduction and asymmetry of emu wings. Their research reveals that the absence of distal muscle formation results in a lack of mechanostress during development, leading to the obser.....»»
Webb Telescope provides another look into galactic collisions
An interaction between an elliptical galaxy and a spiral galaxy, collectively known as Arp 107, seems to have given the spiral a happier outlook thanks to the two bright "eyes" and the wide semicircular "smile." The region has been observed before in.....»»
Enhanced ion diffusion kinetics achieved through interpenetrated structures in electrochemical energy storage devices
As global demand for electrochemical electrodes continues to rise, a new trend has emerged, emphasizing the need to maintain ion diffusion efficiency while accommodating ultra-high loadings of active materials to enhance capacity and energy density......»»
Template synthesis creates multilayered perovskites with unique ferroelectric behavior
A group of Nagoya University researchers in Japan has synthesized 4- and 5-layered versions of the important electrical material perovskite. Analyzing the mechanism of ferroelectricity in the material, they found it has a unique function: the materia.....»»