From chemical graphs to structures
3D configurations of atoms dictate all materials properties. Quantitative predictions of accurate equilibrium structures, 3D coordinates of all atoms, from a chemical graph, a representation of the structural formula, is a challenging and computation.....»»
Microbes feed on iron: New study reveals how they do it
Pipelines, sprinklers, and other infrastructure in oxygen-free environments are vulnerable to microbially induced corrosion (MIC)—a process where microorganisms degrade iron-based structures, potentially leading to costly damages or even collapses......»»
New chemical treatment reduces number of plant pores that regulate water loss
Researchers from Nagoya University Institute of Transformative Biomolecules (WPI-ITbM) in Japan and their colleagues have identified and derivatized a chemical compound that effectively regulates the density of stomata in model plants. Stomata are cr.....»»
"Making insurance effective in the face of climate change may require it to be legally enforced"
Recent hurricanes hitting the Southeastern United States have again robbed people of their homes, businesses and lives. Hurricane Helen, in late September, was followed up last week by Hurricane Milton, collapsing seemingly robust building structures.....»»
3D structures of biomolecules: "Dictionaries" make fluorescence-based data accessible
A research team from Germany and the U.S. led by Heinrich Heine University Düsseldorf (HHU) has developed a data description that can provide results from fluorescence measurements for structural and dynamic modeling of large biomolecules......»»
Chemical trick activates antibiotic directly at the pathogen
Colistin is a last-resort antibiotic that is usually only used for severe infections with resistant bacteria. This is due to its severe kidney-damaging side effects, which occur in about 30% of treated patients. A research team at the Helmholtz Cente.....»»
Butterfly brains reveal the tweaks required for cognitive innovation
A species of tropical butterfly with unusually expanded brain structures displays a fascinating mosaic pattern of neural expansion linked to a cognitive innovation......»»
Key role of structural defects in amorphous solid deformation uncovered
Researchers at the Indian Institute of Science Education and Research (IISER) Pune and the CSIR-National Chemical Laboratory (NCL) Pune have shown that the macroscopic deformation of amorphous solids is controlled by structural defects within the mat.....»»
Discovery of key protein for biosynthesis of plant defense steroids could enhance pest control strategies
Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum......»»
Plant fungus provides new drug target for colorectal cancer therapy
Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide......»»
Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»
Microbiome studies in humans and zoo animals pave the way for new drug development
Microorganisms do not just colonize the body of mammals during infections. Billions of microbes can be found on and in healthy humans and animals at any given time, communicating with each other via chemical signals and thus influencing their health......»»
Plate tectonics drive compositional evolution of the upper mantle, study finds
On present-day Earth, plate subduction continuously modifies the chemical composition of the convecting mantle, and various mantle sources linked to these processes have been widely studied. However, when did global chemical heterogeneity of the conv.....»»
mRNA vaccines for disease outbreaks can be synthesized in less time with new technique
In an era where viral outbreaks can escalate into global pandemics with alarming speed, the ability to quickly develop new vaccines has become crucial. However, the speed of vaccine production is limited because the mRNA used in it is partly chemical.....»»
Janus-like metasurface technology shows different optical responses according to the direction of light
Metasurface technology is an advanced optical technology that is thinner, lighter, and more capable of precisely controlling light through nanometer-sized artificial structures than conventional technologies. KAIST researchers have overcome the limit.....»»
Biological control generates "desirable outcomes" within all One Health dimensions, research reveals
New CABI-led research has revealed that biological control generates "desirable outcomes" within all One Health dimensions—mitigating global change issues such as chemical pollution, biocide resistance, biodiversity loss, and habitat destruction......»»
Scientists discover chemical probes for previously "undruggable" cancer target
Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»
How profits from big pharma"s use of genetic information could revolutionize nature conservation
The blue blood of threatened horseshoe crabs contains a chemical essential for testing the safety of vaccines. So these ancient creatures are highly sought after by pharmaceutical companies worldwide, contributing to declines in their populations......»»
Scientists apply ancient construction methods to help fabricate modern microparticles
Inspired by the ancient East Asian method of constructing wooden structures using a "tongue and groove" technique, Nanyang Technological University, Singapore (NTU Singapore) scientists have developed a new approach to fabricating advanced ceramic mi.....»»
Digital quantum simulation of nuclear magnetic resonance experiments
Programmable quantum computers have the potential to efficiently simulate increasingly complex molecular structures, electronic structures, chemical reactions, and quantum mechanical states in chemistry that classical computers cannot. As the molecul.....»»
Can walls of oysters protect shores against hurricanes? Darpa wants to know.
Colonized artificial reef structures could absorb the power of storms. On October 10, 2018, Tyndall Air Force Base on the Gulf of Mexico—a pillar of American air superiority—f.....»»