Fluidizing the cell membrane: Effective internalization of lipid nanoparticles for photodynamic cancer therapy
In order to deliver cancer therapeutics to tumor cells, the cells' membranes must be overcome. A team of researchers have discovered a simple way to achieve this using lipid nanoparticles containing the reagent EDTA (ethylenediaminetetraacetic acid)......»»
Novel chemical tool for understanding membrane remodeling in the cell
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell......»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Novel triple drug combination effective against antibiotic-resistant bacteria
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»
Researchers develop "founding document" on synthetic cell development
Cells are the fundamental units of life, forming the variety of all living things on Earth as individual cells and multicellular organisms. To better understand how cells perform the essential functions of life, scientists have begun developing synth.....»»
What is cybersecurity mesh architecture (CSMA)?
Cybersecurity mesh architecture (CSMA) is a set of organizing principles used to create an effective security framework. Using a CSMA approach means designing a security architecture that is composable and scalable with easily extensible interfaces,.....»»
Nano-drugs hitching a ride on bacteria could help treat pancreatic cancer
Many pancreatic tumors are like malignant fortresses, surrounded by a dense matrix of collagen and other tissue that shields them from immune cells and immunotherapies that have been effective in treating other cancers. Employing bacteria to infiltra.....»»
Nanotubes, nanoparticles and antibodies detect tiny amounts of fentanyl
A research team at the University of Pittsburgh led by Alexander Star, a chemistry professor in the Kenneth P. Dietrich School of Arts and Sciences, has developed a fentanyl sensor that is six orders of magnitude more sensitive than any electrochemic.....»»
Developing a tech platform for fast, robust series production of nanoparticles
Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are neede.....»»
Bioreactor processes and cryotechnologies improve active ingredient tests using human cell cultures
Many new drug candidates end up failing because they cause serious side effects in clinical trials even though lab tests involving cell cultures have been successful. This is a common occurrence if the cells used come from animal tissue, for example......»»
Investigation reveals varied impact of preschool programs on long-term school success
Early education programs are widely believed to be effective public investments for helping children succeed in school and for reducing income- and race-based achievement gaps. However, a new study conducted by a team of investigators from Teachers C.....»»
Understanding cellular transcription responses to oxygen deprivation
A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences......»»
Antimicrobial peptide from cows shows potential for treating hypervirulent bacteria
University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such infections use to protect themselves from.....»»
U.S. requiring automatic emergency braking, but current tech does little for pedestrians
Federal regulators hailed automatic emergency braking as a key technology in reducing traffic deaths. But it is least effective at night, when the majority of pedestrian deaths happen......»»
Toyota executives like fuel cell technology for zero-emission pickups
A hydrogen pickup would have bigger towing ranges and a fuel-like gasoline truck, Toyota executives say......»»
Study shows a tale of two social media platforms for Donald Trump
Truth Social was more effective at driving news attention toward Donald Trump during the 2022 midterm election cycle than Twitter (now known as X) was during the 2016 primary election season, a pattern driven mostly by partisan media on the left and.....»»
Cell contraction drives the initial shaping of human embryos, study finds
Human embryo compaction, an essential step in the first days of an embryo's development, is driven by the contractility of its cells. This is the finding of a team of scientists from CNRS, Institut Curie, Inserm, AP-HP and the Collège de France. Pub.....»»
Toyota establishes North American hydrogen business headquarters in Los Angeles
The H2HQ facility will do R&D, commercialization and sales for hydrogen fuel cell products......»»
Mercedes-Benz Alabama factory changes CEO weeks before UAW vote
Federico Kochlowski, vice president of operations, will take over as CEO of the Mercedes U.S. assembly plant effective Wednesday......»»
Activity in a room stirs up nanoparticles left over from consumer sprays, study shows
Common household products containing nanoparticles—grains of engineered material so miniscule they are invisible to the eye—could be contributing to a new form of indoor air pollution, according to a Rutgers University study......»»
Anker SOLIX X1 offers effective solar power storage for your home backup
The Anker SOLIX X1 is a home backup and solar power storage solution that incorporates some truly innovative features. You have to read it to believe it......»»