Fluidizing the cell membrane: Effective internalization of lipid nanoparticles for photodynamic cancer therapy
In order to deliver cancer therapeutics to tumor cells, the cells' membranes must be overcome. A team of researchers have discovered a simple way to achieve this using lipid nanoparticles containing the reagent EDTA (ethylenediaminetetraacetic acid)......»»
Nanoparticle delivery of FZD4 to lung endothelial cells inhibits lung cancer progression and metastases
A recent study from the lab of Tanya Kalin, MD, Ph.D., professor of Child Health and Internal Medicine at the University of Arizona College of Medicine—Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung ca.....»»
Emojis make tourism advertising on social media more effective and appealing, finds study
A study by the University of Granada (UGR) shows that users understand advertisements better and with less effort when congruent emojis and messages are used. The findings also suggest a shift in the preferences of potential consumers towards more na.....»»
Nanovials method for immune cell screening uncovers receptors that target prostate cancer
A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor proteins found on their sur.....»»
Scientists share single-cell atlas for the highly regenerative worm, Pristina leidyi
An international team of scientists, including B. Duygu Özpolat at Washington University in St. Louis, has published the first single-cell atlas for Pristina leidyi (Pristina), the water nymph worm, a segmented annelid with extraordinary regenerativ.....»»
A rechargeable nanotorch: Afterglow luminescence imaging tracks cell-based microrobots in real time
An afterglow luminescent nanoprobe opens up new possibilities for imaging living cells. As a research team reports in the journal Angewandte Chemie International Edition, their new "nanotorch" can continue to luminesce for more than 10 days after a s.....»»
US drug shortages reach record high with 323 meds now in short supply
The shortages affect everything from generic cancer drugs to ADHD medication. Enlarge / Takeda Pharmaceutical Co. Adderall XR brand medication arranged at a pharmacy in Provo, Utah, in November 2023. (credit: Getty | George Frey).....»»
Designing a cost-effective X-ray free electron lasers facility
Many advances in structural science since the 1970s were made by probing materials with synchrotron radiation: that is, high energy X-rays generated through accelerating high-energy electrons. The latest generation of such sources, X-ray free electro.....»»
Biologists reveal how gyrase resolves DNA entanglements
Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in every cell in the body have one thing in common; th.....»»
Plant more native trees to reduce landslide risk, control erosion, say researchers
Landslides typically occur under heavy rain. With the potential for increased precipitation due to climate change and a possible return to La Niña reinforcing slopes with native trees and shrubs could be an effective, economical and sustainable solu.....»»
Scientists find new ways to convert inhibitors into degraders, paving the way for future drug discoveries
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells......»»
A new tool for tracing the family trees of cells
EPFL researchers have developed GEMLI, a pioneering tool that could democratize and vastly improve how we study the journey of cells from their embryonic state through to specialized roles in the body, as well as their changes in cancer and other dis.....»»
Cloud engineering could be more effective "painkiller" for global warming than previously thought
Cloud "engineering" could be more effective for climate cooling than previously thought, because of the increased cloud cover produced, new research shows......»»
Write angry thoughts down and shred them, Japan study advises
When you next see red, don't snap at your colleagues or scream into a pillow—writing down your feelings, then shredding or throwing them away is an effective way to calm down, a Japanese study has found......»»
Nearly half of B2B startups choose not to market themselves, researchers find
Marketing is one of the most effective ways for an early-stage business-to-business (B2B) startup firm to grow, yet nearly half of such firms that would benefit from it choose not to do any marketing, according to the findings of a paper co-authored.....»»
Polysaccharide-based membranes with high wet mechanical properties for bone repair
Currently, membrane materials play an important role in tissue repair, especially polysaccharide-based membranes, attracting much attention due to their excellent biological properties. However, poor mechanical properties of polysaccharide-based memb.....»»
New protein imaging method supports the design of innovative new cancer drugs
Scientists have successfully used a new imaging technique to determine the structure and interactions of a protein complex that plays a significant part in the initiation and progression of cancer. They showed that it was possible to use a high-resol.....»»
Self-embedding silver nanoparticles: Researchers find the "silver lining" in cotton gin waste
Cotton gin waste, also known as cotton gin trash, is a byproduct of the cotton ginning process and occurs when the cotton fibers are separated from the seed boll. For cotton gin waste, the treasure is its hidden potential to transform silver ions int.....»»
Scientists reconstruct assembly of the human centriole, image by image, for the first time
Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles." Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to.....»»
EPA seeks to cut “Cancer Alley” pollutants
Chemical plants will have to monitor how much is escaping and stop leaks. Enlarge / An oil refinery in Louisiana. Facilities such as this have led to a proliferation of petrochemical plants in the area. (credit: Art Wager).....»»
How exposure management elevates cyber resilience
Attackers are adept at identifying and exploiting the most cost-effective methods of compromise, highlighting the critical need for organizations to implement asset identification and understand their assets’ security posture in relation to the.....»»