Novel triple drug combination effective against antibiotic-resistant bacteria
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»
Climate change as unjust enrichment: A new legal framework for climate litigation
The climate crisis stands as the most pressing challenge of our generation, yet effective legal responses remain elusive. Political polarization and the influence of special interest groups have stalled meaningful regulatory action on both national a.....»»
Modified ribosomes could be a possible mechanism of antibiotic resistance
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature Communications. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of.....»»
Parasite genome analysis provides a new approach to predicting malaria drug resistance
Researchers at University of California San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance......»»
Scientists reveal structural link for initiation of protein synthesis in bacteria
Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it into protein. But this step has been a visual mys.....»»
Nanopesticide delivery system made with neem seed extract improves pesticide effectiveness
Pesticides can be made more effective and environmentally friendly by improving how they stick to plant surfaces, thanks to new research led by Dr. Mustafa Akbulut, professor of chemical engineering at Texas A&M University......»»
Scientists synthesize unsymmetrical ureas using non-phosgene method
Unsymmetrical ureas can form multiple stable hydrogen bonds with proteins. Since drugs containing urea functional groups display unique biological activities when interacting with their targets, they play an important role in drug development and med.....»»
Study discovers how algae produce a hormone they use to communicate
A study at the University of Cordoba shows how algae produce auxin, a plant hormone, opening a path of communication with bacteria to generate synergies that could benefit agricultural production. The paper is published in the journal iScience......»»
Aesthetics study examines music"s influence on experience of art
Researchers at the Max Planck Institute for Empirical Aesthetics (MPIEA) in Frankfurt am Main, Germany, have investigated how the combination of music and images influences the aesthetic perception of art, and what role the deliberate correspondence.....»»
Targeting bacterial defense mechanisms for effective antibiotic treatment
In addition to the urgent need for new antibiotics, alternative strategies are required to tackle the problem of antibiotic resistance. Michaela Wenzel, Associate Professor at Chalmers University of Technology, is investigating bacterial defenses aga.....»»
How to recognize employment fraud before it becomes a security issue
The combination of remote work, the latest technologies, and never physically meeting your employees has made it very easy for job applicants to mask their true identities from their employer and commit employment fraud. Motivations for this type of.....»»
Trump targets Mexico and Canada with tariffs, plus an extra 10% for China
Tariffs are retaliation for drug trafficking and illegal migration. Donald Trump has said he will impose tariffs of 25 percent on all imports from Canada and Mexico, and an extra.....»»
New mechanism in bacterial DNA enzyme opens pathways for antibiotic development
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent i.....»»
New transformer-based AI model enhances precision in rice leaf disease detection
Rice is one of the world's most essential food crops, but its production is constantly threatened by leaf diseases caused by pathogens such as fungi, bacteria, and viruses. These diseases, which manifest as spots or blotches on leaves, can severely i.....»»
Cyanobacterial circadian clock uses an AM radio-like mechanism to control cellular processes
Cyanobacteria, an ancient lineage of bacteria that perform photosynthesis, have been found to regulate their genes using the same physics principle used in AM radio transmission......»»
Exploring life at its simplest: Scientists create a "minimal cell membrane" with just two lipids
Lipids, or fats, are essential to life. They form the membranes around cells, protecting them from the outside. In nature, there is an enormous diversity of lipids, with each organism having its own unique combination. But what are the minimum lipid.....»»
Scientists develop AI tool for personalized phage therapy as a targeted alternative to antibiotics
With the rapid development of antibiotics in the 1930s, phage therapy—using viruses known as bacteriophages or phages to tackle bacterial infections—fell into oblivion. But as the current rise in antibiotic resistance is making it increasingly di.....»»
M4 Mac minis in a computing cluster is incredibly cool, but not hugely effective
There is a way to use a collection of M4 Mac minis in a cluster, but the benefits only really exist when you use high-end Macs.A cluster of M4 Mac minis - Image credit: Alex Ziskind/YouTubeWhile most people think of having a more powerful computer me.....»»
Researchers create high-resistant starch rice by impaired amylopectin synthesis
Rice is one of the most important staple crops and an excellent starch-provider. Resistant starch (RS) has shown beneficial effects on diabetes, weight management and inflammatory bowel disease......»»
A molecular trap for exotic metals promises improved diagnostics and faster drug development
A group of scientists from IOCB Prague, led by Dr. Miloslav Polášek, have created compounds that are up to a million times more stable than similar substances used in contemporary medicine to treat tumors or as contrast agents for magnetic resonanc.....»»
Educating young people about social media could be far more effective than a ban—Finland can show us how
The federal government's proposed social media ban for under-16s has sparked widespread debate, affecting millions of young Australians, their families and educators. But will it actually work?.....»»