First mRNA stabilizing substance could aid in development of innovative mRNA therapeutics
Messenger RNA–based therapeutics and vaccines are the new hope in the fight against incurable diseases. A commonly used strategy in the development of messenger RNA (mRNA) medicine is based on the destruction of disease-causing mRNA. Achieving the.....»»
Scientists synthesize unsymmetrical ureas using non-phosgene method
Unsymmetrical ureas can form multiple stable hydrogen bonds with proteins. Since drugs containing urea functional groups display unique biological activities when interacting with their targets, they play an important role in drug development and med.....»»
New imaging platform advances 3D visualization of cellular structures at the nanoscale
A team of researchers led by Anna-Karin Gustavsson at Rice University has developed an innovative imaging platform that promises to improve our understanding of cellular structures at the nanoscale......»»
China experiences reduction in food system inequality and carbon footprint alongside economic development
Humans have persistent food needs that trigger considerable greenhouse gas emissions, varying significantly by region. However, the greenhouse gas (GHG) footprint and inequality in the food system are not well assessed within countries......»»
Here’s everything we know so far about Apple’s 5G modem
It’s been a long time since Apple has been working on its own 5G modem. However, development is taking much longer than the company expected – but recent evidence suggests that we’ll see Apple’s first 5G modem next year. Read on as we detail.....»»
Maritime pine seeds remember temperature conditions
The seeds of maritime pines remember the temperatures they experienced during early development. This memory persists in young trees for at least two years after germination. The above discovery was made by researchers at INRAE, CEA, FCBA, the Univer.....»»
Better health diagnostics through genetically engineered embedded sentinel cells
Cells can now be genetically programmed to record their histories within their genomes, a development that could revolutionize the study of developmental and disease processes, according to a collaborative work by researchers from multiple institutio.....»»
Two-way water transfers can ensure reliability and save money during drought in Western US
A study led by researchers at the University of North Carolina at Chapel Hill offers a solution to water scarcity during droughts amid the tug of economic development, population growth and climate uncertainty for water users in Western U.S. states......»»
Domain security posture of Forbes Global 2000 companies
In this Help Net Security video, Vincent D’Angelo, Global Director of Corporate Development and Strategic Alliances with CSC, analyzes the domain security of the Forbes Global 2000. CSC’s 2024 Domain Security Report analyzes the highest and lowes.....»»
Researchers develop light-guided siRNA delivery system based on cyanobacteria
In a study published in Cell Reports Physical Science on Nov. 25, a research team reported the development of an innovative intelligent light-guided biohybrid system, the CTPA/siCSF1R system, to target tumor-associated macrophages (TAMs), thus enabli.....»»
Transformation of UN goals only way forward for sustainable development, say researchers
Climate change is the single biggest threat to the global environment and socio-economic development—demanding an urgent transformation of the United Nations' Sustainable Development Goals (SDGs), according to a new study......»»
New mechanism in bacterial DNA enzyme opens pathways for antibiotic development
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent i.....»»
Scalable production of high-quality organoids: Innovative platform utilizes 3D engineered nanofiber membrane
A research team has successfully developed a platform capable of scalable, uniform production of organoids that mimic biological functions. Their research has recently been published in the journal Nature Communications......»»
Scientists develop AI tool for personalized phage therapy as a targeted alternative to antibiotics
With the rapid development of antibiotics in the 1930s, phage therapy—using viruses known as bacteriophages or phages to tackle bacterial infections—fell into oblivion. But as the current rise in antibiotic resistance is making it increasingly di.....»»
Tim Cook heads to China for supply chain talks with premier
Apple CEO Tim Cook has returned to China for discussions with premier Li Qiang, in discussions to aid both the global supply chain and the Chinese economy.Apple CEO Tim Cook - Image credit: AppleApple's leadership frequently makes visits to China and.....»»
A molecular trap for exotic metals promises improved diagnostics and faster drug development
A group of scientists from IOCB Prague, led by Dr. Miloslav Polášek, have created compounds that are up to a million times more stable than similar substances used in contemporary medicine to treat tumors or as contrast agents for magnetic resonanc.....»»
How to Create a Future of Cheap Energy for All
The WIRED & Octopus Energy Tech Summit in Berlin was bursting with innovative ideas for reaching net zero and on working together at an ever-greater scale......»»
Natural substance from edible cyanobacterium could combat skin aging by enhancing collagen
Cyanobacteria, or blue-green algae, have existed for billions of years, adapting to a diverse range of environments. Their remarkable ability to photosynthesize and make their own food, as well as their adaptability across a variety of habitats, make.....»»
New technique points to unexpected uses for snoRNA across many cell types
Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small nucleolar RNAs (snoRNAs) are a common but overlooked.....»»
Using light to create bioelectronics inside living organisms
Bioelectronics research and development of implants made of electrically conductive materials for disease treatment is advancing rapidly. However, bioelectronic treatment is not without complications. Researchers at Lund University in Sweden have tak.....»»
Engineers refine lipid nanoparticles for better mRNA therapies
Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies. The meth.....»»