New mechanism in bacterial DNA enzyme opens pathways for antibiotic development
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent i.....»»
Cyanobacterial circadian clock uses an AM radio-like mechanism to control cellular processes
Cyanobacteria, an ancient lineage of bacteria that perform photosynthesis, have been found to regulate their genes using the same physics principle used in AM radio transmission......»»
Scientists develop AI tool for personalized phage therapy as a targeted alternative to antibiotics
With the rapid development of antibiotics in the 1930s, phage therapy—using viruses known as bacteriophages or phages to tackle bacterial infections—fell into oblivion. But as the current rise in antibiotic resistance is making it increasingly di.....»»
Milestone legal case from 35 years ago holds important lessons for how courts deal with scientific evidence today
This month marks 35 years of DNA evidence being used in Australian legal cases. But unlike DNA firsts in other countries, Australia's is perhaps the most significant legal milestone that is practically unheard of......»»
A molecular trap for exotic metals promises improved diagnostics and faster drug development
A group of scientists from IOCB Prague, led by Dr. Miloslav Polášek, have created compounds that are up to a million times more stable than similar substances used in contemporary medicine to treat tumors or as contrast agents for magnetic resonanc.....»»
Molecular morphers: DNA-powered gels shape-shift on command
Johns Hopkins engineers have developed gel strips that change shape when given chemical instructions written in DNA code. These "gel automata," measuring just centimeters, can grow or shrink, transforming from one letter or number to another when tri.....»»
Gene regulation study reports surprising results: Extensive regions of DNA belong to multiple gene switches
Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are therefore separated from each other, even if they.....»»
Scientists develop method "tetraplex digital PCR assay" for detecting DNA of invasive snakes in Florida
Scientists at the University of Florida have developed a pioneering tool to bolster Florida's defenses against invasive species: a DNA-based environmental monitoring test that can pinpoint where they've been, aiding eradication efforts......»»
New technique points to unexpected uses for snoRNA across many cell types
Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small nucleolar RNAs (snoRNAs) are a common but overlooked.....»»
Using light to create bioelectronics inside living organisms
Bioelectronics research and development of implants made of electrically conductive materials for disease treatment is advancing rapidly. However, bioelectronic treatment is not without complications. Researchers at Lund University in Sweden have tak.....»»
Study reveals RNA"s unknown role in DNA damage repair
A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role for RNA. Their insights could lead to improved treatments for diseases like cancer and neurodegenerative disorders while chan.....»»
Origin of life research finds RNA can favor both left- and right-handed proteins
The mystery of why life uses molecules with specific orientations has deepened with a discovery that RNA—a key molecule thought to have potentially held the instructions for life before DNA emerged—can favor making the building blocks of proteins.....»»
Transparent worms with glowing proteins may help fertility treatments
The development of maternal egg cells is pivotal for survival—but also precarious. During meiosis, the DNA-containing chromosomes can easily be broken or lost, causing infertility, miscarriage or genetic disorders like Down syndrome. Scientists hav.....»»
DNA-based methods found highly effective for identifying insect species
A team of researchers from Linnaeus University and Linköping University, extensively evaluated DNA barcoding and metabarcoding methods. A comprehensive study has demonstrated that DNA-based methods are remarkably reliable for identifying insect spec.....»»
New structure gives insight into mRNA export and cancers, and how viruses hijack the process to infect their host
The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the nucleus to the site of protein translation in the cytopl.....»»
Scientists uncover cross-species neural mechanism for early detection of life motion in visual processing
Visual systems of both humans and animals can detect life motion from the environment at the earliest stage of visual processing, research by scientists from the Chinese Academy of Sciences (CAS) uncovered......»»
DNA repair by cooperation between proteins: A look inside the cell"s repair hub
New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells......»»
Photon qubits challenge AI, enabling more accurate quantum computing without error-correction techniques
In an era where AI and data are driving the scientific revolution, quantum computing technology is emerging as another game-changer in the development of new drugs and new materials......»»
Zitadel raises $9 million to accelerate product development
Zitadel announced its $9 million Series A funding round led by Nexus Venture Partners with participation from Floodgate. Both firms represent the world’s best experts in open source, developer tools, and identity infrastructure. Zitadel’.....»»
Iron-clad defense: How microbes shield tomato crops from bacterial wilt
Ralstonia solanacearum is a soil-borne pathogen that devastates tomato and other Solanaceae crops globally. Traditional chemical controls have proven inadequate and environmentally damaging......»»
Study: Why Aztec “death whistles” sound like human screams
The basic mechanism relies on the Venturi effect, producing a unique rough and piercing sound. Archaeologists have discovered numerous ceramic or clay whistles at Aztec sites, dub.....»»