Exploring the limits of G protein-coupled receptors
How do signals from outside the cell cause a response inside it? Such outside signals could be hormones or neurotransmitters. To notice them, the cell's surface possesses receptors. One of the key classes of such receptors are so-called G protein-cou.....»»
The best reality shows streaming on Netflix right now (October 2024)
Games that test physical limits or mental agility, fun cooking competitions, and more make up the best reality shows streaming on Netflix right now......»»
Trimer complex TaNF-Y balances grain yield and quality in wheat: Study
Breeding efforts have focused intensively on improving grain yield and quality in wheat (Triticum aestivum L.). Content and composition of grain starch and seed storage protein (SSP) are two critical factors that determine grain yield and quality. St.....»»
Exploring the role of hydrogen sulfide in the expression of iron uptake genes in E. coli
Antibiotic resistance and oxidative stress response are important biological mechanisms that help bacteria thrive, especially pathogenic bacteria like Escherichia coli. Hydrogen sulfide (H2S), a chemical messenger molecule, regulates several intracel.....»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Building better bone grafts: Nanofibrous scaffolds to activate two main collagen receptors in bone cells
Each year, about 2.2 million bone-grafting procedures are performed worldwide, the gold standard of care being autografting, which uses the patient's own bone for tooth implantation and to repair and reconstruct parts of the mouth, face and skull......»»
Shedding light on a decades-old protein sorting mystery
Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, has proposed and validated a mechanism that addresses a decades-old mystery surrounding epi.....»»
Rethinking privacy: A tech expert’s perspective
Data privacy has become one of the most pressing challenges of our time, but it didn’t happen overnight. The proliferation of data collection, coupled with the rise of advanced technologies like artificial intelligence and machine learning, has.....»»
AI trained on evolution"s playbook develops proteins that spur drug and scientific discovery
A new artificial intelligence model developed by researchers at The University of Texas at Austin paves the way for more effective and less toxic treatments and new preventive strategies in medicine. The AI model informs the design of protein-based t.....»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
Chevy woos Equinox EV buyers with Erewhon juice giveaway
Chevy is giving bottles of an electric-blue protein drink to people who test-drive an Equinox EV at an Erewhon organic market in L.A......»»
Improving industrial scale lactoferrin production with synthetic biological systems
Lactoferrin (LF), a multifunctional glycoprotein of the transferrin family, is naturally expressed in human and cow milk. The name "LF" is derived from its ability to bind to iron (ferrin, a suffix indicating iron-binding protein)......»»
Strategies for maximizing recombinant protein production in tobacco plants
Plant molecular farming (PMF) is a modern, sophisticated technology that utilizes plants' biosynthetic machinery to synthesize a plethora of recombinant proteins, including industrial and therapeutic enzymes. It has several advantages over traditiona.....»»
Naked mole-rat found to have lost infection-resistant proteins
Scientists have found that the naked mole-rat—an underground rodent that lives up to 40 years—has lost a number of CD1 functional genes. The CD1 gene family in mammals is responsible for protein synthesis that protects the body against infectious.....»»
Studying fossil extraction on Native lands and exploring the depths of untold histories
In 2019, historian Lukas Rieppel published a book about the history of dinosaur fossils and their excavation in the late 1800s to create museum displays......»»
Increasing protein in staple crops could help alleviate global protein shortage
A Mississippi State biologist's research in improving global nutrition and sustainability is featured this week in New Phytologist......»»
Researchers uncover key insights into cholesterol"s structure in cell membranes
A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. Th.....»»
From chaos to order: Proteins can re-structure themselves to create important substances
The protein "MIPS" changes its internal structure when it becomes active. Its disordered active center becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8,.....»»
New biosensor illuminates physiological signals in living animals
Eric Schreiter and Luke Lavis thought they had figured it out. In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»