Examining mRNA transcription difficulties
The corona pandemic has ensured that the term "mRNA" is now also known to a large public beyond laboratories and lecture halls. However, the molecule is much more than an important component of a successful vaccine against the SARS-CoV-2 virus. "mRNA.....»»
Weaker transcription factors are better when they work together
Bioengineers can tailor the genomes of cells to create "cellular therapies" that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch on bioengineered genes w.....»»
ConcealSherpaAI identifies potentially harmful webpages
Conceal introduced the ConcealSherpaAI engine, a secure browser extension powered by AI to identify potentially harmful webpages autonomously. By examining and evaluating metadata signals on a webpage, ConcealSherpaAI determines whether to quarantine.....»»
37% of third-party applications have high-risk permissions
Email attacks have increased in both sophistication and volume since the start of the year, according to Abnormal Security. Examining data since 2013, Abnormal identified a massive increase in third-party applications (apps) integrated with email, un.....»»
iOS 17 beta 5 Live Voicemail prompt reduces confusion, but it’s still confusing
One of the headlining features of iOS 17 is Live Voicemail, which lets you view a real-time transcription of the message someone is leaving you as they speak. In today’s new iOS 17 beta 5, Apple has made a tweak to the message prompt that callers h.....»»
Managing domestic and wild cats is likely to remain fraught, new research warns
Current efforts to protect and restore native biodiversity is being threatened by difficulties in identifying wild and domestic cats, and categorization is likely to remain fraught for the foreseeable future, experts have warned......»»
MHZ9 modulates ethylene signaling at translational level in rice
Ethylene is a versatile gaseous plant hormone that plays an important role in rice growth, development, and environmental adaptation. Translational control allows the mRNA to be translated in an mRNA-selective, signal-responsive, and rapid manner......»»
Examining the power of host social interactions in bacterial evolution
Previous studies in humans and animals have shown that hosts in a social condition (sharing the same space) harbor a more similar microbiota composition. Microbial transmission between hosts, which is increased when living in the same household, lead.....»»
Examining how atomic nuclei vibrate with a greater degree of precision
Using ultra-high-precision laser spectroscopy on a simple molecule, a group of physicists led by Professor Stephan Schiller Ph.D. from Heinrich Heine University Düsseldorf (HHU) has measured the wave-like vibration of atomic nuclei with an unprecede.....»»
New lipid nanoparticle-mRNA therapy combats melanoma in mouse models
Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells—which play a key role in immune response—that eradicated tumors and prevented their recurrence in mouse models.....»»
Examining how El Niño affects precipitation over the Antarctic Peninsula and West Antarctica
The precipitation in West Antarctica, especially around the Antarctic Peninsula, exhibits large variability on the interannual time scale. In recent years, scientific research activities, tourism and fisheries have been experiencing remarkable growth.....»»
Examining the impact of company selection ability on labor markets
Recently, Cai Xiaoming, associate professor at Peking University HSBC Business School (PHBS), published a collaborative paper titled "Meetings and Mechanisms" in the International Economic Review. The paper delves into the potential impact of compani.....»»
Examining the contribution of cultural heritage values to steppe conservation on ancient burial mounds of Eurasia
During our history, ancient civilizations have considerably shaped the global ecosystems through a coevolution of landscape and local populations. In some cases, the legacy of the disappeared civilizations is still visible in the form of buildings an.....»»
Examining how the world"s largest water striders jump on water
Water striders live on the water surface and their leg length ranges from several to over 100 millimeters. It is well known that they use their long hydrophobic legs and support their bodies on the surface without breaking it. Under each leg, the wat.....»»
Examining how cells talk to each other
Like us, cells communicate. Well, in their own special way. Using waves as their common language, cells tell one another where and when to move. They talk, they share information, and they work together—much like the interdisciplinary team of resea.....»»
UK habitats to be impacted by exposure to climate change—but some more than others
All UK habitats are set to be severely challenged by exposure to climate change in coming years, but some are facing far greater difficulties than others, according to a new paper authored by a University of York researcher......»»
Examining our options for a lunar solar power satellite
The concept of gathering some of the unlimited sunlight available in space, then transmitting it down to users, was first developed to serve the clean energy needs of planet Earth. But Space-Based Solar Power can also work for the moon......»»
Study discovers novel region for BRD4 transcription and potential therapeutic target
A team of investigators in the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a novel protein region responsible for regulating DNA transcription elongati.....»»
DNA-repair protein complex is a shapeshifter, reconfiguring itself to meet the demands of each task
Transcription factor IIH, or TFIIH, pronounced "TF two H," is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the highly regulated enzymatic synthesis of RNA from a D.....»»
Examining why plants flower early in a warming world
Scientists have unveiled a new mechanism that plants use to sense temperature. This finding could lead to solutions to counteract some of the deleterious changes in plant growth, flowering and seed production due to climate change. The results are pu.....»»
Supersize the cell: Unlocking genome secrets through expansion microscopy
The ability to turn genes on or off is fundamental to the diversity we see in cells, in individuals, and even in terms of health and disease. This process, known as gene transcription, involves converting the information stored in our DNA into a "car.....»»