Examining mRNA transcription difficulties
The corona pandemic has ensured that the term "mRNA" is now also known to a large public beyond laboratories and lecture halls. However, the molecule is much more than an important component of a successful vaccine against the SARS-CoV-2 virus. "mRNA.....»»
Rational design of mRNA nanovaccine for cancer immunotherapy
Messenger RNA (mRNA) vaccines are revolutionizing the therapy of cancer. They can be flexibly developed in a short period of time, allowing transient expression of multiple antigens for safe and efficient immunization. A diversity of mRNA vaccines is.....»»
Examining size growth of marine crocodiles in the Jurassic period
The State Museum of Natural History Stuttgart has a globally important collection of marine reptiles with numerous specimens from the time of the so-called Posidonia Shale. The outstanding feature of the ca. 183-182 million year old fossils from sout.....»»
Examining immunoglobulin heavy chain genes and alcohol metabolism-related genes in the Han Chinese population
Understanding the traits that have undergone positive selection during human evolution can provide insight into the events that have shaped our species, as well as into the diseases that continue to plague us today. As the most populated ethnic group.....»»
Ultium Cells EV battery plant in Ohio faces $270,000 in OSHA fines
The U.S. Department of Labor's Occupational Safety and Health Administration said investigators examining the cause of a March 2023 explosion and fire at the plant led the agency to cite the company for 17 serious violations and two other violations.....»»
Examining the role of methylation in vernalization and the photoperiod pathway: A potential flowering regulator?
Recognized as a pivotal developmental transition, flowering marks the continuation of a plant's lifecycle. Flowering time determines the length of plant reproductive period and environmental adaptability. The correct flowering time is very significan.....»»
Vision Pro weight still concerns Apple; prescription lenses a headache for company – Bloomberg
Mark Gurman’s latest newsletter says that Apple remains concerned about the Vision Pro’s weight and is working on making the next generation of the headset lighter. Gurman also describes the difficulties the company is facing in dealing with t.....»»
Examining the toxins in the common tomato
Regardless of how one says "tomato," they all contain tomatine, a toxin in the plant's green fruit, leaves, and roots. Tomatoes produce the bitter-tasting compound—a major plant-specialized metabolite secreted from the roots—to defend against pat.....»»
Examining how bryophytes adapt without gibberellin
When life gets tough, nature usually finds a way to help the little guys......»»
Katalin Karikó’s Nobel Prize Marks the Beginning of an mRNA Vaccine Revolution
Nobel Prize winners Katalin Karikó and Drew Weissman pioneered the technology that produced a Covid-19 vaccine in record time. Next, mRNA could tackle flu, malaria, and HIV......»»
After being demoted and forced to retire, mRNA researcher wins Nobel
Katalin Karikó and Drew Weissman awarded Nobel Prize in Physiology or Medicine. Enlarge (credit: Mark Makela / Stringer) Biochemist Katalin Karikó and immunologist Drew Weissman won the Nobel Prize in Physiology or Med.....»»
Katalin Karikó’s Nobel Prize Marks the Beginning of a Vaccine Revolution
Nobel Prize winners Katalin Karikó and Drew Weissman pioneered the technology that produced a Covid-19 vaccine in record time. Next, mRNA could tackle flu, malaria, and HIV......»»
Kariko, Weissman win Nobel for mRNA COVID vaccines
Katalin Kariko and Drew Weissman won the Nobel Medicine Prize on Monday for work on messenger RNA (mRNA) technology that paved the way for groundbreaking COVID-19 vaccines......»»
Examining ethical considerations for human remains
In 2022, the Penn Museum announced that it would rebury the skulls of dozens of Black Philadelphian individuals whose remains were unethically obtained in the mid-1800s. Some in the community of the individuals' descendants, who felt they were not co.....»»
A better understanding of gene regulation in embryonic stem cells
During the first hours of an embryo's development, specialized molecules called pioneer transcription factors unravel parts of its DNA to activate the encoded genes. Which gene is activated and when has to follow a set schedule so that genes that are.....»»
Examining the genesis of CRISPR"s molecular scissors
Genome engineering may be the future of medicine, but it relies on evolutionary advances made billions of years ago in primordial bacteria, the original masters of gene editing......»»
Examining how weather patterns will change in the future
In a warming Pacific Northwest, summers are getting hotter and winters less cold, but the atmospheric patterns that influence the weather aren't necessarily expected to become stronger or more frequent by the end of the century, according to a new Po.....»»
Towards a better understanding of early human embryonic development
The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some extent in mice, human EGA remains largely unexplore.....»»
New nanopore tech for quicker, more thorough mRNA quality checks
Researchers at The University of Queensland are harnessing the latest sequencing technology developed by UK-based biotech Oxford Nanopore Technologies to analyze mRNA vaccines and therapies......»»
Examining how much wildfire smoke influences air quality trends
Stanford research reveals the rapidly growing influence of wildfire smoke on air quality trends across most of the United States. Wildfire smoke in recent years has slowed or reversed progress toward cleaner air in 35 states, erasing a quarter of gai.....»»
Synthetic biology tool comprehensively reveals gene regulatory networks in E. coli
The intricate interplay of gene expression within living cells is akin to a well-orchestrated symphony, with each gene playing its part in perfect harmony to ensure cells function as they should. At the heart of this symphony are transcription factor.....»»