Examining the genesis of CRISPR"s molecular scissors
Genome engineering may be the future of medicine, but it relies on evolutionary advances made billions of years ago in primordial bacteria, the original masters of gene editing......»»
Team develops an epigenome editing toolkit to dissect the mechanisms of gene regulation
Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory regions, and epigenetic mo.....»»
A multi-stream network for retrosynthesis prediction
Retrosynthesis aims to predict a set of reactants for producing given molecules, which plays a significant part in the biochemistry field, such as molecular pathway design and drug discovery. Most existing methods only benefit from one kind of inform.....»»
Strictly no dancing: Researchers discover "new molecular design rules"
Since the discovery of quantum mechanics more than a hundred years ago, it has been known that electrons in molecules can be coupled to the motion of the atoms that make up the molecules. Often referred to as molecular vibrations, the motion of atoms.....»»
In Tesla Autopilot probe, U.S. prosecutors focus on securities, wire fraud
U.S. prosecutors are examining whether Tesla committed securities or wire fraud by misleading investors and consumers about its electric vehicles’ self-driving capabilities, three people familiar with the matter told Reuters. .....»»
Researchers discover new function of oncoproteins
Researchers at the University of Würzburg have discovered a new function of the oncoprotein MYCN: It not only helps cancer cells to grow stronger, but also makes them more resistant to drugs. The study is published in Molecular Cell......»»
Educational research should pinpoint anti-Black aggressions to build better policy, scholar writes
Educational research has long lumped all people of color together when examining microaggressions perpetrated against them. A University of Kansas scholar has published an article that argues educational research should instead study anti-Black aggre.....»»
Researchers develop nanotechnology for creating wafer-scale nanoparticle monolayers in seconds
Nanoscale materials present us with astonishing chemical and physical properties that help materialize applications such as single molecular sensing and minimally invasive photothermal therapy—which were once just theories—into reality......»»
Study reveals flaw in long-accepted approximation used in water simulations
Computational scientists at the Department of Energy's Oak Ridge National Laboratory have published a study in the Journal of Chemical Theory and Computation that questions a long-accepted factor in simulating the molecular dynamics of water: the 2-f.....»»
Researchers reveal how molecular roadblocks slow the breakdown of cellulose for biofuels
Cellulose, which helps give plant cell walls their rigid structure, holds promise as a renewable raw material for biofuels—if researchers can accelerate the production process. Compared to the breakdown of other biofuel materials like corn, breakin.....»»
Microbiome studies help explore treatments for genetic disorders
A collaboration has led to the identification, in a bacterium of the intestine, of new CRISPR-Cas9 molecules that could have a clinical potential to treat genetic diseases such as retinitis pigmentosa, through sub-retinal injections. Anna Cereseto an.....»»
Rich molecular language guides tiny liquid droplet formation in cells
Peering into a biological cell reveals a bustling microscopic world. The workhorses within this realm are specialized structures called organelles that perform vital cellular functions. Curiously, some organelles defy accepted convention: Instead of.....»»
Attosecond core-level spectroscopy reveals real-time molecular dynamics
Chemical reactions are complex mechanisms. Many different dynamic processes are involved, affecting both the electrons and the nucleus of the present atoms. Very often, the strongly coupled electron and nuclear dynamics induce radiation-less relaxati.....»»
First steps toward a whole-body map of molecular responses to exercise
Research definitively confirms that muscle-moving, calorie-burning activity slows the advance of disease, improves cognitive function, boosts the immune system, and reduces rates of mortality from all causes......»»
Researchers detect toxic chemicals in aquatic organisms with new AI method
Swedish researchers at Chalmers University of Technology and the University of Gothenburg have developed an AI method that improves the identification of toxic chemicals—based solely on knowledge of the molecular structure......»»
The academic sleuth facing death threats and ingratitude
Lonni Besançon devotes evenings and weekends to rarely appreciated sanitation work. By examining scientific articles after they are published and exposing shortcomings, he has made himself an enemy of both researchers and publishers. It has gone so.....»»
Tracking the dynamics of biomolecules with optofluidic antennas
In order to better understand fundamental processes in life science at the molecular level, the precise observation of single molecule dynamics is of utmost interest. However, current techniques based on fluorescence measurements in aqueous solutions.....»»
CRISPR is promising to tackle antimicrobial resistance, but bacteria can fight back
In his presentation "How to use CRISPR-Cas to combat AMR" at the ESCMID Global Congress, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Repub.....»»
Experts develop way to harness CRISPR technology to deal with antimicrobial resistance
Antimicrobial resistance (AMR) is continuing to increase globally, with rates of AMR in most pathogens increasing and threatening a future in which every day medical procedures may no longer be possible and infections thought long dealt with could ki.....»»
Genesis" Claudia Marquez: We"re "becoming completely independent" from Hyundai in U.S.
The premium spinoff is becoming more independent from its mainstream counterpart with stronger brand awareness, new products and strong sales......»»
More efficient molecular motor widens potential applications
Light-driven molecular motors were first developed nearly 25 years ago at the University of Groningen, the Netherlands. This resulted in a shared Nobel Prize for Chemistry for Professor Ben Feringa in 2016. However, making these motors do actual work.....»»