Examining mRNA transcription difficulties
The corona pandemic has ensured that the term "mRNA" is now also known to a large public beyond laboratories and lecture halls. However, the molecule is much more than an important component of a successful vaccine against the SARS-CoV-2 virus. "mRNA.....»»
Scientists publish novel research on how individual cells respond to viral infection
A team of scientists from Montana State University recently published unique research examining how individual cells respond to viral infection. The work used state-of-the-art technology to culture cells and track infection in real time; it is the fi.....»»
Difficulties in exploiting the economic opportunities in the ocean
The green shift has created a strong interest in exploiting the economic opportunities in the ocean, but the ocean is not so easily economized. This is revealed in a comprehensive study, which, among other things, shows how the cod resists being dome.....»»
Gender diversity found to improve corporate social responsibility
A study in the International Journal of Business Excellence examining the relationship between gender diversity on corporate boards and corporate social responsibility spending has found a positive correlation. The research focused on 738 firms acros.....»»
How cells manage their mRNA stockpile and its output
In a typical cell, genes encoded in DNA are used to make messenger RNA (mRNA), which is used to make proteins, and this process of gene expression keeps the cell running. Gene expression is regulated in each cell such that specific genes are turned o.....»»
Drones could help map the lunar surface with extreme precision
Exploring the moon has become increasingly more of a focal point lately, especially with a series of landers recently launched with various degrees of success. One of the difficulties those landers and any future human missions face is understanding.....»»
Transcription factors that regulate development of light organs and bioluminescence in firefly identified
Two bio-researchers, one with Huazhong Agricultural University, the other the Firefly Conservation Research Center, both in China, have identified the key transcription factors that regulate the development of light organs and bioluminescence in the.....»»
Uncovering the role of FOXO1 in vascular development and transcriptional dynamics in endothelial cells
FOXO1, a key transcription factor in cellular processes, governs metabolism, apoptosis, and aging. Despite its significance, the comprehensive regulation of FOXO1 in endothelial cells (EC) remains unexplored......»»
Alternative splicing and transcription factor interplay in blood orange anthocyanin biosynthesis
The blood orange, renowned for its vibrant color due to anthocyanins, is a focus of increasing demand in the nutraceutical industry, with 'Tarocco' [C. sinensis (L.) Osbeck] being the most widespread variety. Current research sheds light on the genet.....»»
Hydrogel spheres compose a microporous structure for localized mRNA delivery
In a significant leap forward in the realm of regenerative medicine, a team at the Terasaki Institute for Biomedical Innovation has introduced a pioneering approach to mRNA therapy using microspheres made of gelatin methacryloyl (GelMA)—a gelatin-b.....»»
House lawmakers say more research needed to understand EV battery fire risks
A House subcommittee says first responders are not prepared to handle the novel difficulties and dangers of EV fires......»»
Unlocking the color code: The role of VvBBX44 and VvMYBA1 in regulating grape anthocyanin biosynthesis
Anthocyanins significantly influence grape quality and color, with transcription factors HY5 and MYBA1 playing pivotal roles in their biosynthesis. Recent findings show that VvBBX44, a B-box protein, inhibits anthocyanin production in grapes by suppr.....»»
RNA-sequencing analysis reveals key genes behind eggplant peel variation
Anthocyanins give fruits and vegetables their red, purple, and blue colors, offering health benefits. Their biosynthesis involves specific enzymes and is regulated by the MBW complex of transcription factors. Research has linked color variations in p.....»»
New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control
Inspired by the design of space shuttles, Penn Engineering researchers have invented a new way to synthesize a key component of lipid nanoparticles (LNPs), the revolutionary delivery vehicle for mRNA treatments including the Pfizer-BioNTech and Moder.....»»
Examining the relationship of reproductive health and economics
Access to reproductive health care—and abortion in particular—is an issue that resonates with voters' deeply held personal beliefs and reflects their underlying moral, philosophical, and religious views. But is it also an economic issue?.....»»
Neurobiology: Examining how bats distinguish different sounds
Seba's short-tailed bat (Carollia perspicillata) lives in the subtropical and tropical forests of Central and South America, where it mostly feeds on pepper fruit. The animals spend their days in groups of 10 to 100 individuals in hollow trunks and r.....»»
Examining a century of change in a New York City urban forest
There haven't been many long-term studies on urban forests, but data collected from the Thain Family Forest, which the New York Botanical Garden (NYBG) has been stewarding for more than a century, has provided an opportunity for scientists from The F.....»»
Examining viruses that can help "dial up" carbon capture in the sea
Armed with a catalog of hundreds of thousands of DNA and RNA virus species in the world's oceans, scientists are now zeroing in on the viruses most likely to combat climate change by helping trap carbon dioxide in seawater or, using similar technique.....»»
Stabilizing mRNA vaccines for delivery to cells
Vaccines and therapies based on messenger RNA could be more readily delivered due to a non-toxic polymer that protects RNA and controls its release inside cells......»»
Researchers shed light on river resiliency to flooding
Researchers at the University of Nevada, Reno have completed one of the most extensive river resilience studies, examining how river ecosystems recover following floods. They developed a novel modeling approach that used data from oxygen sensors plac.....»»
Discovery of a subset of human short introns that are spliced out by a novel mechanism
The well-known essential pre-mRNA splicing factor U2AF heterodimer (U2AF2–U2AF1) has been identified as mediating early splicing reactions in all introns of different lengths. However, Dr. Kazuhiro Fukumura in the Akila Mayeda lab at Fujita Health.....»»